STRINGSTRING
CREB1 CREB1 NRP1 NRP1 LGMN LGMN BCAR1 BCAR1 IL10 IL10 RELA RELA APPL2 APPL2 M3YU90_MUSPF M3YU90_MUSPF VIL1 VIL1 APPL1 APPL1 SIRT2 SIRT2 HGF HGF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CREB1cAMP responsive element binding protein 1. (341 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
LGMNLegumain. (433 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (867 aa)
IL10Interleukin 10. (220 aa)
RELARELA proto-oncogene, NF-kB subunit. (511 aa)
APPL2Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (660 aa)
M3YU90_MUSPFMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (616 aa)
VIL1Villin 1. (827 aa)
APPL1Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (672 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (412 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (725 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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