STRINGSTRING
EDNRA EDNRA SMAD6 SMAD6 PRICKLE1 PRICKLE1 LRP2 LRP2 PKD2 PKD2 CHD7 CHD7 NKX3-1 NKX3-1 HES1 HES1 HECTD1 HECTD1 FOXH1 FOXH1 JAG1 JAG1 ACVRL1 ACVRL1 SEC24B SEC24B DLL4 DLL4 BMPR1A BMPR1A TFAP2B TFAP2B PRDM1 PRDM1 EYA1 EYA1 FKBP10 FKBP10 EGR2 EGR2 DCTN5 DCTN5 COL3A1 COL3A1 LOX LOX SRF SRF TAB1 TAB1 PROX1 PROX1 ENG ENG TFAP2E TFAP2E TBX2 TBX2 NGFR NGFR NPRL3 NPRL3 SUFU SUFU PLXND1 PLXND1 LOXL1 LOXL1 APLNR APLNR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
SMAD6Mothers against decapentaplegic homolog. (494 aa)
PRICKLE1Prickle planar cell polarity protein 1. (832 aa)
LRP2LDL receptor related protein 2. (4699 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (915 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2522 aa)
NKX3-1NK3 homeobox 1. (231 aa)
HES1Hes family bHLH transcription factor 1. (283 aa)
HECTD1HECT domain E3 ubiquitin protein ligase 1. (2610 aa)
FOXH1Forkhead box H1. (398 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
SEC24BSEC24 homolog B, COPII coat complex component. (1285 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (533 aa)
TFAP2BTranscription factor AP-2 beta. (476 aa)
PRDM1PR/SET domain 1. (818 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (621 aa)
FKBP10Peptidylprolyl isomerase. (582 aa)
EGR2Early growth response 2. (485 aa)
DCTN5Dynactin subunit 5. (185 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
LOXLysyl oxidase. (415 aa)
SRFSerum response factor. (508 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa)
PROX1Prospero homeobox 1. (737 aa)
ENGEndoglin. (653 aa)
TFAP2ETranscription factor AP-2 epsilon. (433 aa)
TBX2T-box transcription factor 2. (679 aa)
NGFRNerve growth factor receptor. (429 aa)
NPRL3NPR3 like, GATOR1 complex subunit. (569 aa)
SUFUSuppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (484 aa)
PLXND1Plexin D1. (1746 aa)
LOXL1Lysyl oxidase like 1. (495 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (380 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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