STRINGSTRING
IL23A IL23A VTCN1 VTCN1 CD40LG CD40LG M3XS76_MUSPF M3XS76_MUSPF GPAM GPAM IL27RA IL27RA HES1 HES1 IL18 IL18 TFRC TFRC CD3E CD3E CCL19 CCL19 EFNB1 EFNB1 M3XZP3_MUSPF M3XZP3_MUSPF SLC7A1 SLC7A1 FADD FADD M3Y079_MUSPF M3Y079_MUSPF CD86 CD86 PDCD1LG2 PDCD1LG2 M3Y0N5_MUSPF M3Y0N5_MUSPF CD274 CD274 PTPN22 PTPN22 CD81 CD81 NCKAP1L NCKAP1L IGF2 IGF2 LEP LEP TYK2 TYK2 M3Y653_MUSPF M3Y653_MUSPF TNFSF9 TNFSF9 IL6ST IL6ST KITLG KITLG CD80 CD80 ANXA1 ANXA1 RPS3 RPS3 NCK1 NCK1 PPP3CA PPP3CA M3YDY7_MUSPF M3YDY7_MUSPF M3YE36_MUSPF M3YE36_MUSPF HHLA2 HHLA2 AGER AGER PTPRC PTPRC STAT5A STAT5A STAT5B STAT5B NCK2 NCK2 RIPK2 RIPK2 TNFSF13B TNFSF13B AIF1 AIF1 PYCARD PYCARD TRAF6 TRAF6 IGF1 IGF1 M3YKW3_MUSPF M3YKW3_MUSPF CORO1A CORO1A ZP4 ZP4 SPTA1 SPTA1 IL12B IL12B IL6 IL6 FOXP3 FOXP3 M3YRT8_MUSPF M3YRT8_MUSPF CD6 CD6 M3YUJ9_MUSPF M3YUJ9_MUSPF TNFSF4 TNFSF4 IL12RB1 IL12RB1 ZP3 ZP3 RASAL3 RASAL3 IL15 IL15 IL2RA IL2RA PRKCQ PRKCQ TNFRSF13C TNFRSF13C IGFBP2 IGFBP2 IL21 IL21 IL2 IL2 SASH3 SASH3 CARD11 CARD11 M3XM17_MUSPF M3XM17_MUSPF CD28 CD28
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IL23AInterleukin 23 subunit alpha. (195 aa)
VTCN1V-set domain containing T cell activation inhibitor 1. (318 aa)
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (260 aa)
M3XS76_MUSPFIg-like domain-containing protein. (263 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (828 aa)
IL27RAInterleukin 27 receptor subunit alpha. (654 aa)
HES1Hes family bHLH transcription factor 1. (283 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
TFRCTransferrin receptor protein 1. (770 aa)
CD3ECD3 epsilon antigen. (186 aa)
CCL19C-C motif chemokine. (108 aa)
EFNB1Ephrin B1; Belongs to the ephrin family. (346 aa)
M3XZP3_MUSPFHMG box domain-containing protein. (215 aa)
SLC7A1Solute carrier family 7 member 1. (629 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (216 aa)
M3Y079_MUSPFUncharacterized protein. (369 aa)
CD86CD86 molecule. (330 aa)
PDCD1LG2Programmed cell death 1 ligand 2. (272 aa)
M3Y0N5_MUSPFIg-like domain-containing protein. (341 aa)
CD274CD274 molecule. (303 aa)
PTPN22Protein tyrosine phosphatase non-receptor type 22. (679 aa)
CD81Tetraspanin. (287 aa)
NCKAP1LNCK associated protein 1 like. (1134 aa)
IGF2Insulin like growth factor 2. (192 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (166 aa)
TYK2Tyrosine-protein kinase. (1182 aa)
M3Y653_MUSPFProtein kinase domain-containing protein. (212 aa)
TNFSF9TNF superfamily member 9; Belongs to the tumor necrosis factor family. (244 aa)
IL6STInterleukin 6 signal transducer. (918 aa)
KITLGKIT ligand. (274 aa)
CD80CD80 molecule. (302 aa)
ANXA1Annexin. (345 aa)
RPS3Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa)
NCK1Cytoplasmic protein. (378 aa)
PPP3CASerine/threonine-protein phosphatase. (461 aa)
M3YDY7_MUSPFUncharacterized protein. (257 aa)
M3YE36_MUSPFUncharacterized protein. (77 aa)
HHLA2HERV-H LTR-associating 2. (400 aa)
AGERAdvanced glycosylation end-product specific receptor. (400 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1298 aa)
STAT5ASignal transducer and activator of transcription. (794 aa)
STAT5BSignal transducer and activator of transcription. (691 aa)
NCK2Cytoplasmic protein. (380 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa)
TNFSF13BTNF superfamily member 13b; Belongs to the tumor necrosis factor family. (290 aa)
AIF1Allograft inflammatory factor 1. (147 aa)
PYCARDPYD and CARD domain containing. (193 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
IGF1Insulin like growth factor 1. (153 aa)
M3YKW3_MUSPFRING-type domain-containing protein. (326 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
ZP4Zona pellucida glycoprotein 4. (472 aa)
SPTA1Spectrin alpha, erythrocytic 1. (2434 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (331 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (210 aa)
FOXP3Forkhead box P3. (433 aa)
M3YRT8_MUSPFIg-like domain-containing protein. (339 aa)
CD6CD6 molecule. (672 aa)
M3YUJ9_MUSPFHMG box domain-containing protein. (171 aa)
TNFSF4TNF superfamily member 4; Belongs to the tumor necrosis factor family. (183 aa)
IL12RB1Interleukin 12 receptor subunit beta 1. (716 aa)
ZP3Zona pellucida glycoprotein C. (426 aa)
RASAL3RAS protein activator like 3. (1014 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
IL2RAInterleukin 2 receptor subunit alpha. (267 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
TNFRSF13CTNF receptor superfamily member 13C. (187 aa)
IGFBP2Insulin like growth factor binding protein 2. (277 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (153 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (152 aa)
SASH3SAM and SH3 domain containing 3. (380 aa)
CARD11Caspase recruitment domain family member 11. (1153 aa)
M3XM17_MUSPFUncharacterized protein. (208 aa)
CD28CD28 molecule. (255 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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