STRINGSTRING
CCN4 CCN4 PDK4 PDK4 ADCY8 ADCY8 RACK1 RACK1 M3XP97_MUSPF M3XP97_MUSPF LEPR LEPR G6PC2 G6PC2 GCG GCG KLF7 KLF7 ZBTB20 ZBTB20 PRKAA2 PRKAA2 WFS1 WFS1 GPI GPI SLC12A6 SLC12A6 PRCP PRCP M3YA21_MUSPF M3YA21_MUSPF HK2 HK2 INSR INSR STK11 STK11 BACE2 BACE2 FAM3B FAM3B M3YBQ0_MUSPF M3YBQ0_MUSPF TFAP2B TFAP2B GAS6 GAS6 CNR1 CNR1 ALOX5 ALOX5 PTPRN2 PTPRN2 FOXO3 FOXO3 PLSCR3 PLSCR3 AGER AGER NOX4 NOX4 CYP7A1 CYP7A1 SLC2A4 SLC2A4 STAT3 STAT3 IGF1R IGF1R M3YHM7_MUSPF M3YHM7_MUSPF ADIPOR1 ADIPOR1 TFAP2E TFAP2E NR1D1 NR1D1 CSMD2 CSMD2 NGFR NGFR PDK2 PDK2 M3YWA8_MUSPF M3YWA8_MUSPF MLXIPL MLXIPL M3YXD0_MUSPF M3YXD0_MUSPF FOXA1 FOXA1 M3YY40_MUSPF M3YY40_MUSPF FOXK1 FOXK1 CAV3 CAV3 RAF1 RAF1 PIK3CA PIK3CA SIN3A SIN3A KCNB1 KCNB1 NCOA5 NCOA5 HNF4A HNF4A ADIPOR2 ADIPOR2 GCK GCK GPR1 GPR1 GPER1 GPER1 M3Z5Z4_MUSPF M3Z5Z4_MUSPF M3Z655_MUSPF M3Z655_MUSPF VGF VGF ASPSCR1 ASPSCR1 PAX6 PAX6 PCK1 PCK1 GCGR GCGR NR1H4 NR1H4 KAT5 KAT5 M3YK20_MUSPF M3YK20_MUSPF FBN1 FBN1 NUCKS1 NUCKS1 SIRT1 SIRT1 APPL2 APPL2 CRY1 CRY1 SESN3 SESN3 M3YLM3_MUSPF M3YLM3_MUSPF HK3 HK3 ADGRF5 ADGRF5 LOC101677498 LOC101677498 BAD BAD LRRC8A LRRC8A INPP5K INPP5K IL6 IL6 RPH3AL RPH3AL BHLHA15 BHLHA15 CSRP3 CSRP3 RFX6 RFX6 CARTPT CARTPT PIK3R1 PIK3R1 PRKAA1 PRKAA1 ERN1 ERN1 PTCH1 PTCH1 PARK7 PARK7 HIF1A HIF1A PCK2 PCK2 M3Y3R5_MUSPF M3Y3R5_MUSPF CRY2 CRY2 INS INS FOXA3 FOXA3 CYB5R4 CYB5R4 PYGL PYGL PDX1 PDX1 SLC37A4 SLC37A4 SOX4 SOX4 M3Y079_MUSPF M3Y079_MUSPF LRRC8D LRRC8D M3XZF1_MUSPF M3XZF1_MUSPF HKDC1 HKDC1 HK1 HK1 PTPN2 PTPN2 SIDT2 SIDT2 MCU MCU TRPV4 TRPV4 SLC39A14 SLC39A14 MBD5 MBD5 RBM4 RBM4 ADIPOQ ADIPOQ HNF1A HNF1A RAB11FIP2 RAB11FIP2 TRA2B TRA2B STXBP3 STXBP3 SLC8B1 SLC8B1 M3XU21_MUSPF M3XU21_MUSPF CSMD1 CSMD1 M3XTZ9_MUSPF M3XTZ9_MUSPF PTPN11 PTPN11 HECTD4 HECTD4 RMI1 RMI1 ADRA2A ADRA2A M3XSG3_MUSPF M3XSG3_MUSPF TCF7L2 TCF7L2 CCDC186 CCDC186 MBD6 MBD6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CCN4Cellular communication network factor 4. (367 aa)
PDK4Protein-serine/threonine kinase. (412 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
RACK1WD_REPEATS_REGION domain-containing protein. (317 aa)
M3XP97_MUSPFANK_REP_REGION domain-containing protein. (132 aa)
LEPRLeptin receptor. (1164 aa)
G6PC2Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (356 aa)
GCGGlucagon. (180 aa)
KLF7Kruppel like factor 7. (302 aa)
ZBTB20Zinc finger and BTB domain containing 20. (741 aa)
PRKAA2Non-specific serine/threonine protein kinase. (524 aa)
WFS1Wolframin ER transmembrane glycoprotein. (888 aa)
GPIGlucose-6-phosphate isomerase; Belongs to the GPI family. (508 aa)
SLC12A6Solute carrier family 12 member 6. (1150 aa)
PRCPProlylcarboxypeptidase. (497 aa)
M3YA21_MUSPFWD_REPEATS_REGION domain-containing protein. (467 aa)
HK2Hexokinase 2. (917 aa)
INSRTyrosine-protein kinase receptor. (1352 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (443 aa)
BACE2Beta-secretase 2; Belongs to the peptidase A1 family. (439 aa)
FAM3BFamily with sequence similarity 3 member B. (181 aa)
M3YBQ0_MUSPFSelenoprotein T; Belongs to the SelWTH family. Selenoprotein T subfamily. (137 aa)
TFAP2BTranscription factor AP-2 beta. (476 aa)
GAS6Growth arrest specific 6. (541 aa)
CNR1Cannabinoid receptor 1; Belongs to the G-protein coupled receptor 1 family. (411 aa)
ALOX5Arachidonate 5-lipoxygenase. (674 aa)
PTPRN2Protein tyrosine phosphatase receptor type N2. (953 aa)
FOXO3Forkhead box O3. (671 aa)
PLSCR3Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (307 aa)
AGERAdvanced glycosylation end-product specific receptor. (400 aa)
NOX4NADPH oxidase 4. (578 aa)
CYP7A1Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (501 aa)
SLC2A4Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
M3YHM7_MUSPFFork-head domain-containing protein. (528 aa)
ADIPOR1Adiponectin receptor 1. (375 aa)
TFAP2ETranscription factor AP-2 epsilon. (433 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (613 aa)
CSMD2CUB and Sushi multiple domains 2. (3298 aa)
NGFRNerve growth factor receptor. (429 aa)
PDK2Protein-serine/threonine kinase. (482 aa)
M3YWA8_MUSPFUncharacterized protein. (726 aa)
MLXIPLMLX interacting protein like. (857 aa)
M3YXD0_MUSPFFork-head domain-containing protein. (575 aa)
FOXA1Forkhead box A1. (501 aa)
M3YY40_MUSPFDUF3496 domain-containing protein. (376 aa)
FOXK1Forkhead box K1. (614 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (644 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
SIN3ASIN3 transcription regulator family member A. (1550 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (858 aa)
NCOA5Nuclear receptor coactivator 5. (579 aa)
HNF4AHepatocyte nuclear factor 4 alpha. (443 aa)
ADIPOR2Adiponectin receptor 2. (385 aa)
GCKPhosphotransferase. (473 aa)
GPR1G protein-coupled receptor 1; Belongs to the G-protein coupled receptor 1 family. (355 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (359 aa)
M3Z5Z4_MUSPFFABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa)
M3Z655_MUSPFFABP domain-containing protein. (134 aa)
VGFVGF nerve growth factor inducible. (617 aa)
ASPSCR1ASPSCR1 tether for SLC2A4, UBX domain containing. (462 aa)
PAX6Paired box 6. (436 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
GCGRGlucagon receptor; Belongs to the G-protein coupled receptor 2 family. (488 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (472 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa)
M3YK20_MUSPFWD_REPEATS_REGION domain-containing protein. (237 aa)
FBN1Fibrillin 1. (2877 aa)
NUCKS1Nuclear casein kinase and cyclin dependent kinase substrate 1. (243 aa)
SIRT1Sirtuin 1. (557 aa)
APPL2Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (660 aa)
CRY1Cryptochrome circadian regulator 1. (587 aa)
SESN3Sestrin 3. (495 aa)
M3YLM3_MUSPFV-SNARE coiled-coil homology domain-containing protein. (496 aa)
HK3Hexokinase 3. (924 aa)
ADGRF5Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1386 aa)
LOC101677498DUF3496 domain-containing protein. (265 aa)
BADBCL2 associated agonist of cell death. (168 aa)
LRRC8ALeucine rich repeat containing 8 VRAC subunit A. (810 aa)
INPP5KInositol polyphosphate-5-phosphatase K. (473 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (210 aa)
RPH3ALRabphilin 3A like (without C2 domains). (301 aa)
BHLHA15Basic helix-loop-helix family member a15. (187 aa)
CSRP3Cysteine and glycine rich protein 3. (194 aa)
RFX6Regulatory factor X6. (928 aa)
CARTPTCART prepropeptide. (116 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
PRKAA1Non-specific serine/threonine protein kinase. (517 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (975 aa)
PTCH1Patched 1. (1386 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (824 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (620 aa)
M3Y3R5_MUSPFUncharacterized protein. (137 aa)
CRY2Cryptochrome circadian regulator 2. (594 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (109 aa)
FOXA3Forkhead box A3. (351 aa)
CYB5R4Cytochrome b5 reductase 4. (520 aa)
PYGLAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (858 aa)
PDX1Pancreatic and duodenal homeobox 1. (283 aa)
SLC37A4Solute carrier family 37 member 4. (429 aa)
SOX4SRY-box transcription factor 4. (269 aa)
M3Y079_MUSPFUncharacterized protein. (369 aa)
LRRC8DLeucine rich repeat containing 8 VRAC subunit D. (912 aa)
M3XZF1_MUSPFPhosphotransferase. (133 aa)
HKDC1Hexokinase domain containing 1. (704 aa)
HK1Hexokinase 1. (917 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (388 aa)
SIDT2SID1 transmembrane family member 2. (832 aa)
MCUMitochondrial calcium uniporter. (350 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (873 aa)
SLC39A14Solute carrier family 39 member 14. (490 aa)
MBD5Methyl-CpG binding domain protein 5. (1733 aa)
RBM4RNA binding motif protein 4. (365 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (244 aa)
HNF1AHNF1 homeobox A. (633 aa)
RAB11FIP2RAB11 family interacting protein 2. (331 aa)
TRA2BTransformer 2 beta homolog. (288 aa)
STXBP3Syntaxin binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (512 aa)
SLC8B1Solute carrier family 8 member B1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (588 aa)
M3XU21_MUSPFSelenoprotein T; Belongs to the SelWTH family. Selenoprotein T subfamily. (129 aa)
CSMD1CUB and Sushi multiple domains 1. (2957 aa)
M3XTZ9_MUSPFUncharacterized protein. (207 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
HECTD4HECT domain E3 ubiquitin protein ligase 4. (3998 aa)
RMI1RecQ mediated genome instability 1. (564 aa)
ADRA2AAdrenoceptor alpha 2A; Belongs to the G-protein coupled receptor 1 family. (323 aa)
M3XSG3_MUSPFCTNNB1_binding domain-containing protein. (169 aa)
TCF7L2Transcription factor 7 like 2. (514 aa)
CCDC186Coiled-coil domain containing 186. (905 aa)
MBD6Methyl-CpG binding domain protein 6. (1006 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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