STRINGSTRING
ABCC9 ABCC9 LRRC55 LRRC55 DRD3 DRD3 STK39 STK39 PTK2B PTK2B AKAP6 AKAP6 M3XQH2_MUSPF M3XQH2_MUSPF M3XSB1_MUSPF M3XSB1_MUSPF NEDD4 NEDD4 KLHL24 KLHL24 OXSR1 OXSR1 KCNAB1 KCNAB1 NETO2 NETO2 AMIGO1 AMIGO1 DLG1 DLG1 LRRC52 LRRC52 DRD2 DRD2 WNK2 WNK2 KCNQ1 KCNQ1 ITGB1 ITGB1 RNF207 RNF207 KCNAB2 KCNAB2 FXYD1 FXYD1 CAV1 CAV1 WWP2 WWP2 KCNH2 KCNH2 DLG2 DLG2 M3Y9V8_MUSPF M3Y9V8_MUSPF KEL KEL KCNAB3 KCNAB3 ATP1B2 ATP1B2 KCNIP3 KCNIP3 FLNA FLNA DPP6 DPP6 WNK4 WNK4 VIP VIP DPP10 DPP10 WNK3 WNK3 M3YJV6_MUSPF M3YJV6_MUSPF ATP1B3 ATP1B3 ACTN2 ACTN2 KCNIP1 KCNIP1 KIF5B KIF5B TREM2 TREM2 TREML1 TREML1 LRRC26 LRRC26 GNB2 GNB2 LRRC38 LRRC38 NEDD4L NEDD4L GRP GRP NETO1 NETO1 KCNIP4 KCNIP4 KCNIP2 KCNIP2 CRBN CRBN KCNG1 KCNG1 KCNS1 KCNS1 WNK1 WNK1 GCK GCK AMIGO2 AMIGO2 PRNP PRNP KCNA5 KCNA5 KCNE2 KCNE2 M3Z6U8_MUSPF M3Z6U8_MUSPF KCNE3 KCNE3 KCNS2 KCNS2 KCNE4 KCNE4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABCC9Uncharacterized protein. (1071 aa)
LRRC55Leucine rich repeat containing 55. (318 aa)
DRD3Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (447 aa)
STK39Serine/threonine kinase 39. (546 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
AKAP6A-kinase anchoring protein 6. (2319 aa)
M3XQH2_MUSPFUncharacterized protein. (130 aa)
M3XSB1_MUSPFUncharacterized protein. (296 aa)
NEDD4E3 ubiquitin-protein ligase. (904 aa)
KLHL24Kelch like family member 24. (600 aa)
OXSR1Oxidative stress responsive kinase 1. (461 aa)
KCNAB1Potassium voltage-gated channel subfamily A member regulatory beta subunit 1. (401 aa)
NETO2Neuropilin and tolloid like 2. (525 aa)
AMIGO1Adhesion molecule with Ig like domain 1. (493 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (927 aa)
LRRC52Leucine rich repeat containing 52. (315 aa)
DRD2D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. (443 aa)
WNK2WNK lysine deficient protein kinase 2. (1899 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (590 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
RNF207Ring finger protein 207. (639 aa)
KCNAB2Potassium voltage-gated channel subfamily A regulatory beta subunit 2. (382 aa)
FXYD1FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (92 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
WWP2E3 ubiquitin-protein ligase. (872 aa)
KCNH2Potassium voltage-gated channel subfamily H member 2. (1159 aa)
DLG2Uncharacterized protein. (833 aa)
M3Y9V8_MUSPFV-SNARE coiled-coil homology domain-containing protein. (119 aa)
KELKell metallo-endopeptidase (Kell blood group). (691 aa)
KCNAB3Potassium voltage-gated channel subfamily A regulatory beta subunit 3. (405 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
KCNIP3Potassium voltage-gated channel interacting protein 3. (284 aa)
FLNAFilamin A. (2647 aa)
DPP6Dipeptidyl peptidase like 6; Belongs to the peptidase S9B family. (803 aa)
WNK4WNK lysine deficient protein kinase 4. (1242 aa)
VIPVasoactive intestinal peptide. (170 aa)
DPP10Dipeptidyl peptidase like 10; Belongs to the peptidase S9B family. (800 aa)
WNK3WNK lysine deficient protein kinase 3. (1731 aa)
M3YJV6_MUSPFABC transmembrane type-1 domain-containing protein. (493 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (253 aa)
ACTN2Actinin alpha 2. (894 aa)
KCNIP1Potassium voltage-gated channel interacting protein 1. (227 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (963 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (230 aa)
TREML1Triggering receptor expressed on myeloid cells like 1. (314 aa)
LRRC26Leucine rich repeat containing 26. (246 aa)
GNB2G protein subunit beta 2. (340 aa)
LRRC38Leucine rich repeat containing 38. (299 aa)
NEDD4LNEDD4 like E3 ubiquitin protein ligase. (999 aa)
GRPGastrin releasing peptide. (147 aa)
NETO1Neuropilin and tolloid like 1. (533 aa)
KCNIP4Potassium voltage-gated channel interacting protein 4. (213 aa)
KCNIP2Kv channel-interacting protein 2; Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Modulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates KCND2/Kv4.2 and KCND3/Kv4.3 currents. Involved in KCND2 and KCND3 trafficking to the cell surface. Essential for the expression of I(To) currents in the heart. Required for normal protein levels of KCND2 in the heart ventricle (By similarity); Belongs to the recoverin family. (252 aa)
CRBNCereblon. (444 aa)
KCNG1Potassium voltage-gated channel modifier subfamily G member 1; Belongs to the potassium channel family. (516 aa)
KCNS1Potassium voltage-gated channel modifier subfamily S member 1; Belongs to the potassium channel family. (498 aa)
WNK1WNK lysine deficient protein kinase 1. (2832 aa)
GCKPhosphotransferase. (473 aa)
AMIGO2Adhesion molecule with Ig like domain 2. (521 aa)
PRNPMajor prion protein; Its primary physiological function is unclear. Has cytoprotective activity against internal or environmental stresses. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan s [...] (257 aa)
KCNA5Potassium voltage-gated channel subfamily A member 5; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium- selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane (By similarity). Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA5, and possibly other family [...] (601 aa)
KCNE2Potassium voltage-gated channel subfamily E regulatory subunit 2. (123 aa)
M3Z6U8_MUSPFSmall ubiquitin-related modifier. (100 aa)
KCNE3Potassium voltage-gated channel subfamily E regulatory subunit 3. (99 aa)
KCNS2Potassium voltage-gated channel modifier subfamily S member 2; Belongs to the potassium channel family. (477 aa)
KCNE4Potassium voltage-gated channel subfamily E regulatory subunit 4. (170 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
Server load: medium (56%) [HD]