(34 nodes) Response to alkaloid network (Mustela putorius)

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second shell of interactors

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Your Input:
	SLC6A3	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (626 aa)
	DRD3	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (447 aa)
	M3XNQ3_MUSPF	DUF4502 domain-containing protein. (379 aa)
	M3XPZ1_MUSPF	DUF4503 domain-containing protein. (370 aa)
	ADCY8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
	OPRM1	Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (401 aa)
	CASP7	Caspase 7; Belongs to the peptidase C14A family. (301 aa)
	PPP2R2A	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (487 aa)
	DRD2	D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. (443 aa)
	HOMER1	Homer scaffold protein 1. (354 aa)
	CRHBP	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa)
	TMEM38B	Transmembrane protein 38B. (291 aa)
	CDK5	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	RAD51	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (340 aa)
	PRKCG	Non-specific serine/threonine protein kinase. (569 aa)
	EHMT2	Euchromatic histone lysine methyltransferase 2. (1270 aa)
	SLC1A2	Amino acid transporter. (579 aa)
	PRKCE	Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa)
	TRPV1	Transient receptor potential cation channel subfamily V member 1. (770 aa)
	RYR2	Ryanodine receptor 2. (4966 aa)
	RECQL5	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (986 aa)
	ABAT	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (518 aa)
	PRKAA1	Non-specific serine/threonine protein kinase. (517 aa)
	M3YU18_MUSPF	Uncharacterized protein. (148 aa)
	PPP1R1B	Protein phosphatase 1 regulatory inhibitor subunit 1B. (206 aa)
	SLC1A3	Amino acid transporter. (542 aa)
	PPP1R9B	Protein phosphatase 1 regulatory subunit 9B. (820 aa)
	HOMER2	Homer scaffold protein 2. (386 aa)
	BLM	BLM RecQ like helicase. (1221 aa)
	TMEM38A	Transmembrane protein 38A. (303 aa)
	SDK1	Sidekick cell adhesion molecule 1. (1502 aa)
	TGM2	Transglutaminase 2. (687 aa)
	RYR1	Ryanodine receptor 1. (4983 aa)
	DRD5	Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family. (474 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY8	PRKCG	ENSMPUP00000001384	ENSMPUP00000010076	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Non-specific serine/threonine protein kinase.	0.870
BLM	M3XNQ3_MUSPF	ENSMPUP00000015547	ENSMPUP00000000703	BLM RecQ like helicase.	DUF4502 domain-containing protein.	0.431
BLM	M3XPZ1_MUSPF	ENSMPUP00000015547	ENSMPUP00000001141	BLM RecQ like helicase.	DUF4503 domain-containing protein.	0.555
BLM	RAD51	ENSMPUP00000015547	ENSMPUP00000008483	BLM RecQ like helicase.	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]	0.960
BLM	RECQL5	ENSMPUP00000015547	ENSMPUP00000013730	BLM RecQ like helicase.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.508
CDK5	PPP1R1B	ENSMPUP00000008272	ENSMPUP00000014887	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.	Protein phosphatase 1 regulatory inhibitor subunit 1B.	0.944
DRD2	DRD3	ENSMPUP00000003847	ENSMPUP00000000275	D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	0.830
DRD2	DRD5	ENSMPUP00000003847	ENSMPUP00000019672	D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.	Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family.	0.866
DRD2	PPP1R1B	ENSMPUP00000003847	ENSMPUP00000014887	D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.	Protein phosphatase 1 regulatory inhibitor subunit 1B.	0.540
DRD2	PPP2R2A	ENSMPUP00000003847	ENSMPUP00000003153	D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	0.852
DRD2	SLC6A3	ENSMPUP00000003847	ENSMPUP00000007617	D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.920
DRD3	DRD2	ENSMPUP00000000275	ENSMPUP00000003847	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.	0.830
DRD3	DRD5	ENSMPUP00000000275	ENSMPUP00000019672	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family.	0.866
DRD3	PPP2R2A	ENSMPUP00000000275	ENSMPUP00000003153	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	0.478
DRD3	SLC6A3	ENSMPUP00000000275	ENSMPUP00000007617	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.516
DRD5	DRD2	ENSMPUP00000019672	ENSMPUP00000003847	Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family.	D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.	0.866
DRD5	DRD3	ENSMPUP00000019672	ENSMPUP00000000275	Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family.	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	0.866
HOMER1	HOMER2	ENSMPUP00000004951	ENSMPUP00000015445	Homer scaffold protein 1.	Homer scaffold protein 2.	0.944
HOMER2	HOMER1	ENSMPUP00000015445	ENSMPUP00000004951	Homer scaffold protein 2.	Homer scaffold protein 1.	0.944
M3XNQ3_MUSPF	BLM	ENSMPUP00000000703	ENSMPUP00000015547	DUF4502 domain-containing protein.	BLM RecQ like helicase.	0.431