STRINGSTRING
TJP3 TJP3 HEG1 HEG1 TGFB2 TGFB2 ADAM10 ADAM10 M3Y080_MUSPF M3Y080_MUSPF PKP2 PKP2 CTNND1 CTNND1 SMAD3 SMAD3 HDAC7 HDAC7 PKP4 PKP4 DSP DSP XIRP2 XIRP2 SMAD7 SMAD7 EXT1 EXT1 MTSS1 MTSS1 M3XRC5_MUSPF M3XRC5_MUSPF M3XRC9_MUSPF M3XRC9_MUSPF POF1B POF1B VCL VCL CLDN1 CLDN1 CLDN16 CLDN16 DLG1 DLG1 NUMB NUMB DLG5 DLG5 PAK2 PAK2 TRPV4 TRPV4 ARVCF ARVCF CLDN25 CLDN25 RHOB RHOB CLDN3 CLDN3 CLDN4 CLDN4 CLDN5 CLDN5 M3Z898_MUSPF M3Z898_MUSPF CDH22 CDH22 CSK CSK ECT2 ECT2 M3Z091_MUSPF M3Z091_MUSPF PRKCI PRKCI CD9 CD9 LIMS2 LIMS2 EPHA4 EPHA4 FSCN1 FSCN1 CDH19 CDH19 CDH7 CDH7 CDH20 CDH20 OCEL1 OCEL1 CLDN15 CLDN15 CDH10 CDH10 CDH9 CDH9 CDH6 CDH6 GRHL2 GRHL2 MPP7 MPP7 PECAM1 PECAM1 PRKCA PRKCA MARVELD2 MARVELD2 CSF1R CSF1R CLDN19 CLDN19 RHOA RHOA FBF1 FBF1 PLEKHA7 PLEKHA7 NF2 NF2 GRHL1 GRHL1 SRF SRF KIRREL1 KIRREL1 FCRL5 FCRL5 ARL2 ARL2 CLDN10 CLDN10 TGFB3 TGFB3 NR1H4 NR1H4 CTNNB1 CTNNB1 PTPRO PTPRO M3YIF4_MUSPF M3YIF4_MUSPF M3YIE9_MUSPF M3YIE9_MUSPF TJP1 TJP1 CLDN8 CLDN8 CLDN14 CLDN14 M3Z5M2_MUSPF M3Z5M2_MUSPF CLDN20 CLDN20 GJA5 GJA5 CLDN2 CLDN2 GJB6 GJB6 CDH18 CDH18 GJB2 GJB2 CLDN9 CLDN9 M3Z8L1_MUSPF M3Z8L1_MUSPF CLDN23 CLDN23 M3Z899_MUSPF M3Z899_MUSPF JUP JUP TBCD TBCD SNAI2 SNAI2 LIMS1 LIMS1 CXADR CXADR PKP1 PKP1 INAVA INAVA CLDN7 CLDN7 RAMP2 RAMP2 ZNF703 ZNF703 M3YDW6_MUSPF M3YDW6_MUSPF FLNA FLNA CLDN18 CLDN18 JAM3 JAM3 PKN2 PKN2 ILDR1 ILDR1 CDH8 CDH8 CDH11 CDH11 CDH5 CDH5 EPB41L3 EPB41L3 RHOC RHOC HIPK1 HIPK1 FERMT2 FERMT2 GNPAT GNPAT M3Y2F6_MUSPF M3Y2F6_MUSPF F2RL1 F2RL1 F2R F2R NPHS1 NPHS1 ESAM ESAM PARD6A PARD6A CDH24 CDH24 CD177 CD177 LSR LSR PLEC PLEC SVEP1 SVEP1 PATJ PATJ M3Y931_MUSPF M3Y931_MUSPF MARVELD3 MARVELD3 WDR1 WDR1 DLG2 DLG2 UGT8 UGT8 CAMSAP3 CAMSAP3 CDH12 CDH12 PKP3 PKP3 WNT11 WNT11 PKHD1 PKHD1 FRMPD2 FRMPD2 CCM2 CCM2 NUMBL NUMBL FLCN FLCN TGFB1 TGFB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TJP3Tight junction protein 3. (708 aa)
HEG1Heart development protein with EGF like domains 1. (1278 aa)
TGFB2Transforming growth factor beta-2 proprotein; Transforming growth factor beta-2 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively. Transforming growth factor beta-2: Multifunctional protein that regulates various processes such as angiogenesis and heart development (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transfor [...] (414 aa)
ADAM10ADAM metallopeptidase domain 10. (737 aa)
M3Y080_MUSPFUncharacterized protein. (202 aa)
PKP2Plakophilin 2. (836 aa)
CTNND1Catenin delta 1. (967 aa)
SMAD3Mothers against decapentaplegic homolog. (414 aa)
HDAC7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (991 aa)
PKP4Plakophilin 4. (1193 aa)
DSPDesmoplakin. (2236 aa)
XIRP2Xin actin binding repeat containing 2. (3308 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
MTSS1MTSS I-BAR domain containing 1. (687 aa)
M3XRC5_MUSPFPDZ domain-containing protein. (185 aa)
M3XRC9_MUSPFPDZ domain-containing protein. (343 aa)
POF1BPOF1B actin binding protein. (580 aa)
VCLVinculin. (1134 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
CLDN16Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (254 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (927 aa)
NUMBNUMB endocytic adaptor protein. (653 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1922 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (873 aa)
ARVCFARVCF delta catenin family member. (960 aa)
CLDN25Claudin 25. (215 aa)
RHOBRas homolog family member B. (196 aa)
CLDN3Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
CLDN4Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
M3Z898_MUSPFClaudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
CDH22Cadherin 22; Cadherins are calcium-dependent cell adhesion proteins. (705 aa)
CSKTyrosine-protein kinase. (450 aa)
ECT2Epithelial cell transforming 2. (914 aa)
M3Z091_MUSPFClaudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (207 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (638 aa)
CD9Tetraspanin. (226 aa)
LIMS2LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (341 aa)
EPHA4EPH receptor A4. (986 aa)
FSCN1Fascin. (493 aa)
CDH19Cadherin 19; Cadherins are calcium-dependent cell adhesion proteins. (771 aa)
CDH7Cadherin 7; Cadherins are calcium-dependent cell adhesion proteins. (785 aa)
CDH20Cadherin 20; Cadherins are calcium-dependent cell adhesion proteins. (801 aa)
OCEL1Occludin/ELL domain containing 1. (264 aa)
CLDN15Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (234 aa)
CDH10Cadherin 10; Cadherins are calcium-dependent cell adhesion proteins. (788 aa)
CDH9Cadherin 9; Cadherins are calcium-dependent cell adhesion proteins. (789 aa)
CDH6Cadherin 6; Cadherins are calcium-dependent cell adhesion proteins. (790 aa)
GRHL2Grainyhead like transcription factor 2. (727 aa)
MPP7Membrane palmitoylated protein 7; Belongs to the MAGUK family. (576 aa)
PECAM1Platelet and endothelial cell adhesion molecule 1. (739 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (688 aa)
MARVELD2MARVEL domain containing 2. (561 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (978 aa)
CLDN19Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa)
RHOARas homolog family member A. (193 aa)
FBF1Fas binding factor 1. (1160 aa)
PLEKHA7Pleckstrin homology domain containing A7. (1251 aa)
NF2Neurofibromin 2. (591 aa)
GRHL1Grainyhead like transcription factor 1. (583 aa)
SRFSerum response factor. (508 aa)
KIRREL1Kirre like nephrin family adhesion molecule 1. (746 aa)
FCRL5Fc receptor like 5. (892 aa)
ARL2ARL2-SNX15 readthrough (NMD candidate); Belongs to the small GTPase superfamily. Arf family. (184 aa)
CLDN10Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (229 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (472 aa)
CTNNB1Catenin beta 1. (781 aa)
PTPROProtein tyrosine phosphatase receptor type O. (1212 aa)
M3YIF4_MUSPFUncharacterized protein. (817 aa)
M3YIE9_MUSPFUncharacterized protein. (230 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1770 aa)
CLDN8Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (225 aa)
CLDN14Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (237 aa)
M3Z5M2_MUSPFUncharacterized protein. (213 aa)
CLDN20Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (219 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
CLDN2Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (230 aa)
GJB6Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (261 aa)
CDH18Cadherin 18; Cadherins are calcium-dependent cell adhesion proteins. (617 aa)
GJB2Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (226 aa)
CLDN9Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa)
M3Z8L1_MUSPFClaudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (221 aa)
CLDN23Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (291 aa)
M3Z899_MUSPFClaudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (207 aa)
JUPJunction plakoglobin. (744 aa)
TBCDTubulin folding cofactor D. (1130 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
LIMS1LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (337 aa)
CXADRUncharacterized protein. (386 aa)
PKP1Plakophilin 1. (696 aa)
INAVAInnate immunity activator. (656 aa)
CLDN7Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
RAMP2Receptor activity modifying protein 2. (194 aa)
ZNF703Zinc finger protein 703. (545 aa)
M3YDW6_MUSPFUncharacterized protein; Belongs to the MAGUK family. (1112 aa)
FLNAFilamin A. (2647 aa)
CLDN18Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (259 aa)
JAM3Junctional adhesion molecule 3. (305 aa)
PKN2Protein kinase N2. (983 aa)
ILDR1Immunoglobulin like domain containing receptor 1. (546 aa)
CDH8Cadherin 8; Cadherins are calcium-dependent cell adhesion proteins. (799 aa)
CDH11Cadherin 11; Cadherins are calcium-dependent cell adhesion proteins. (796 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (783 aa)
EPB41L3Erythrocyte membrane protein band 4.1 like 3. (1094 aa)
RHOCRas homolog family member C. (193 aa)
HIPK1Homeodomain interacting protein kinase 1. (1210 aa)
FERMT2Fermitin family member 2. (706 aa)
GNPATDihydroxyacetone phosphate acyltransferase. (679 aa)
M3Y2F6_MUSPFUncharacterized protein. (181 aa)
F2RL1F2R like trypsin receptor 1. (397 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (426 aa)
NPHS1NPHS1 adhesion molecule, nephrin. (1242 aa)
ESAMEndothelial cell adhesion molecule. (393 aa)
PARD6APar-6 family cell polarity regulator alpha. (346 aa)
CDH24Cadherin 24; Cadherins are calcium-dependent cell adhesion proteins. (688 aa)
CD177CD177 molecule. (443 aa)
LSRLipolysis stimulated lipoprotein receptor. (578 aa)
PLECPlectin. (4655 aa)
SVEP1Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1. (3337 aa)
PATJPATJ crumbs cell polarity complex component. (1803 aa)
M3Y931_MUSPFUncharacterized protein. (203 aa)
MARVELD3MARVEL domain containing 3. (385 aa)
WDR1WD repeat domain 1. (629 aa)
DLG2Uncharacterized protein. (833 aa)
UGT8UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (469 aa)
CAMSAP3Calmodulin regulated spectrin associated protein family member 3. (1485 aa)
CDH12Cadherin 12; Cadherins are calcium-dependent cell adhesion proteins. (794 aa)
PKP3Plakophilin 3. (810 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
PKHD1PKHD1 ciliary IPT domain containing fibrocystin/polyductin. (4056 aa)
FRMPD2FERM and PDZ domain containing 2. (1316 aa)
CCM2CCM2 scaffold protein. (426 aa)
NUMBLNUMB like endocytic adaptor protein. (593 aa)
FLCNUDENN FLCN/SMCR8-type domain-containing protein. (579 aa)
TGFB1Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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