STRINGSTRING
MMP8 MMP8 TMEM147 TMEM147 CLEC7A CLEC7A DDAH1 DDAH1 CD34 CD34 PTX3 PTX3 PKD2 PKD2 ESR1 ESR1 DDAH2 DDAH2 TNF TNF ATP2B4 ATP2B4 ASS1 ASS1 ZC3H12A ZC3H12A AGXT2 AGXT2 M3YXN6_MUSPF M3YXN6_MUSPF IFNG IFNG PTGIS PTGIS OPRM1 OPRM1 TLR4 TLR4 PTK2B PTK2B SMAD3 SMAD3 INSR INSR CAV1 CAV1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MMP8Matrix metallopeptidase 8. (473 aa)
TMEM147Transmembrane protein 147. (187 aa)
CLEC7AC-type lectin domain containing 7A. (248 aa)
DDAH1Dimethylarginine dimethylaminohydrolase 1. (285 aa)
CD34CD34 molecule. (385 aa)
PTX3Pentraxin 3. (381 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (915 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (597 aa)
DDAH2Dimethylarginine dimethylaminohydrolase 2. (288 aa)
TNFTumor necrosis factor alpha; Belongs to the tumor necrosis factor family. (233 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1206 aa)
ASS1Argininosuccinate synthase 1. (412 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (576 aa)
AGXT2Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (516 aa)
M3YXN6_MUSPFUncharacterized protein. (464 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity). (166 aa)
PTGISProstaglandin I2 synthase; Belongs to the cytochrome P450 family. (444 aa)
OPRM1Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (401 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (833 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
SMAD3Mothers against decapentaplegic homolog. (414 aa)
INSRTyrosine-protein kinase receptor. (1352 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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