node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGXT2 | DDAH1 | ENSMPUP00000015022 | ENSMPUP00000005402 | Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Dimethylarginine dimethylaminohydrolase 1. | 0.833 |
AGXT2 | DDAH2 | ENSMPUP00000015022 | ENSMPUP00000010940 | Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Dimethylarginine dimethylaminohydrolase 2. | 0.491 |
ASS1 | DDAH1 | ENSMPUP00000012603 | ENSMPUP00000005402 | Argininosuccinate synthase 1. | Dimethylarginine dimethylaminohydrolase 1. | 0.423 |
ASS1 | DDAH2 | ENSMPUP00000012603 | ENSMPUP00000010940 | Argininosuccinate synthase 1. | Dimethylarginine dimethylaminohydrolase 2. | 0.417 |
ASS1 | M3YXN6_MUSPF | ENSMPUP00000012603 | ENSMPUP00000016096 | Argininosuccinate synthase 1. | Uncharacterized protein. | 0.999 |
ASS1 | PTK2B | ENSMPUP00000012603 | ENSMPUP00000000871 | Argininosuccinate synthase 1. | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. | 0.654 |
CAV1 | ESR1 | ENSMPUP00000007166 | ENSMPUP00000010404 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | 0.890 |
CAV1 | IFNG | ENSMPUP00000007166 | ENSMPUP00000017401 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity). | 0.452 |
CAV1 | TLR4 | ENSMPUP00000007166 | ENSMPUP00000001697 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] | Toll like receptor 4; Belongs to the Toll-like receptor family. | 0.537 |
CAV1 | TNF | ENSMPUP00000007166 | ENSMPUP00000011297 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] | Tumor necrosis factor alpha; Belongs to the tumor necrosis factor family. | 0.420 |
CD34 | IFNG | ENSMPUP00000002930 | ENSMPUP00000017401 | CD34 molecule. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity). | 0.541 |
CD34 | TNF | ENSMPUP00000002930 | ENSMPUP00000011297 | CD34 molecule. | Tumor necrosis factor alpha; Belongs to the tumor necrosis factor family. | 0.535 |
CLEC7A | IFNG | ENSMPUP00000006344 | ENSMPUP00000017401 | C-type lectin domain containing 7A. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity). | 0.518 |
CLEC7A | TLR4 | ENSMPUP00000006344 | ENSMPUP00000001697 | C-type lectin domain containing 7A. | Toll like receptor 4; Belongs to the Toll-like receptor family. | 0.718 |
CLEC7A | TNF | ENSMPUP00000006344 | ENSMPUP00000011297 | C-type lectin domain containing 7A. | Tumor necrosis factor alpha; Belongs to the tumor necrosis factor family. | 0.575 |
DDAH1 | AGXT2 | ENSMPUP00000005402 | ENSMPUP00000015022 | Dimethylarginine dimethylaminohydrolase 1. | Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.833 |
DDAH1 | ASS1 | ENSMPUP00000005402 | ENSMPUP00000012603 | Dimethylarginine dimethylaminohydrolase 1. | Argininosuccinate synthase 1. | 0.423 |
DDAH2 | AGXT2 | ENSMPUP00000010940 | ENSMPUP00000015022 | Dimethylarginine dimethylaminohydrolase 2. | Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.491 |
DDAH2 | ASS1 | ENSMPUP00000010940 | ENSMPUP00000012603 | Dimethylarginine dimethylaminohydrolase 2. | Argininosuccinate synthase 1. | 0.417 |
ESR1 | CAV1 | ENSMPUP00000010404 | ENSMPUP00000007166 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] | 0.890 |