STRINGSTRING
FAXDC2 FAXDC2 CASP10 CASP10 CASP8 CASP8 RIPK1 RIPK1 CREB1 CREB1 NEDD9 NEDD9 PRKDC PRKDC TRIB1 TRIB1 IL23A IL23A NOTCH2 NOTCH2 RB1 RB1 CD101 CD101 TNFSF11 TNFSF11 PRMT1 PRMT1 M3XTK1_MUSPF M3XTK1_MUSPF BRD1 BRD1 RCOR1 RCOR1 TESC TESC THPO THPO CSF1 CSF1 FADD FADD HOXA5 HOXA5 HCLS1 HCLS1 INPP5D INPP5D RHEX RHEX ABCB10 ABCB10 TAL1 TAL1 STAT1 STAT1 PLA2G3 PLA2G3 ANKRD54 ANKRD54 LIF LIF TREM2 TREM2 GATA1 GATA1 TREML1 TREML1 CD74 CD74 ISG15 ISG15 SCIN SCIN PPARGC1B PPARGC1B PRKCA PRKCA CSF3 CSF3 M3YU90_MUSPF M3YU90_MUSPF DCSTAMP DCSTAMP KLF10 KLF10 KAT7 KAT7 FES FES PITHD1 PITHD1 CD4 CD4 IFNG IFNG TGFB1 TGFB1 INHBA INHBA EVI2B EVI2B GPR68 GPR68 NCKAP1L NCKAP1L SMAP1 SMAP1 FAM210B FAM210B HIF1A HIF1A JAG1 JAG1 HSF1 HSF1 POU4F2 POU4F2 ZFP36L1 ZFP36L1 KITLG KITLG ACVR1B ACVR1B M3Y8U3_MUSPF M3Y8U3_MUSPF ETS1 ETS1 LEF1 LEF1 IL17A IL17A FOS FOS SLC9B2 SLC9B2 PPP3CA PPP3CA FOXO3 FOXO3 IL34 IL34 STAT3 STAT3 STAT5B STAT5B TMEM64 TMEM64 TNF TNF TRAF6 TRAF6 RAB7B RAB7B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FAXDC2Fatty acid hydroxylase domain containing 2; Belongs to the sterol desaturase family. (334 aa)
CASP10Caspase 10; Belongs to the peptidase C14A family. (545 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (484 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (646 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (835 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4110 aa)
TRIB1Tribbles pseudokinase 1. (372 aa)
IL23AInterleukin 23 subunit alpha. (195 aa)
NOTCH2Notch receptor 2. (2471 aa)
RB1RB transcriptional corepressor 1. (948 aa)
CD101CD101 molecule. (934 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (321 aa)
PRMT1Protein arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (374 aa)
M3XTK1_MUSPFUncharacterized protein. (44 aa)
BRD1Bromodomain containing 1. (1188 aa)
RCOR1REST corepressor 1. (376 aa)
TESCTescalcin. (214 aa)
THPOThrombopoietin. (325 aa)
CSF1Colony stimulating factor 1. (517 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (216 aa)
HOXA5Homeobox A5. (270 aa)
HCLS1Hematopoietic cell-specific Lyn substrate 1. (474 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1188 aa)
RHEXRegulator of hemoglobinization and erythroid cell expansion. (173 aa)
ABCB10ATP binding cassette subfamily B member 10. (566 aa)
TAL1TAL bHLH transcription factor 1, erythroid differentiation factor. (346 aa)
STAT1Signal transducer and activator of transcription. (750 aa)
PLA2G3Phospholipase A2 group III. (510 aa)
ANKRD54Ankyrin repeat domain 54. (299 aa)
LIFLIF interleukin 6 family cytokine. (202 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (230 aa)
GATA1GATA binding protein 1. (414 aa)
TREML1Triggering receptor expressed on myeloid cells like 1. (314 aa)
CD74CD74 molecule. (279 aa)
ISG15ISG15 ubiquitin like modifier. (184 aa)
SCINScinderin. (715 aa)
PPARGC1BPPARG coactivator 1 beta. (1027 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (688 aa)
CSF3Colony stimulating factor 3. (204 aa)
M3YU90_MUSPFMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (616 aa)
DCSTAMPDendrocyte expressed seven transmembrane protein. (440 aa)
KLF10Kruppel like factor 10. (480 aa)
KAT7Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (583 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (820 aa)
PITHD1PITH domain containing 1. (211 aa)
CD4CD4. (462 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity). (166 aa)
TGFB1Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa)
INHBAInhibin subunit beta A. (424 aa)
EVI2BEcotropic viral integration site 2B. (455 aa)
GPR68G protein-coupled receptor 68; Belongs to the G-protein coupled receptor 1 family. (360 aa)
NCKAP1LNCK associated protein 1 like. (1134 aa)
SMAP1Small ArfGAP 1. (471 aa)
FAM210BFamily with sequence similarity 210 member B. (192 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (824 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
HSF1Heat shock transcription factor 1. (555 aa)
POU4F2POU domain protein. (408 aa)
ZFP36L1ZFP36 ring finger protein like 1. (317 aa)
KITLGKIT ligand. (274 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (494 aa)
M3Y8U3_MUSPFUncharacterized protein. (114 aa)
ETS1ETS proto-oncogene 1, transcription factor. (443 aa)
LEF1Lymphoid enhancer binding factor 1. (400 aa)
IL17AInterleukin 17A. (153 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (446 aa)
SLC9B2Solute carrier family 9 member B2. (538 aa)
PPP3CASerine/threonine-protein phosphatase. (461 aa)
FOXO3Forkhead box O3. (671 aa)
IL34Interleukin 34. (236 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
STAT5BSignal transducer and activator of transcription. (691 aa)
TMEM64Transmembrane protein 64. (285 aa)
TNFTumor necrosis factor alpha; Belongs to the tumor necrosis factor family. (233 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
RAB7BRAB7B, member RAS oncogene family. (200 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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