(49 nodes) Positive regulation of neuron differentiation network (Mustela putorius)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RNF112	Ring finger protein 112. (605 aa)
	BMP6	Bone morphogenetic protein 6. (426 aa)
	DLX1	Distal-less homeobox 1. (255 aa)
	DLX2	Distal-less homeobox 2. (332 aa)
	BEND6	BEN domain containing 6. (291 aa)
	IRX3	Iroquois homeobox 3. (502 aa)
	BCL6	BCL6 transcription repressor. (706 aa)
	BRINP3	BMP/retinoic acid inducible neural specific 3. (766 aa)
	REST	RE1 silencing transcription factor. (1098 aa)
	ARHGEF2	Rho/Rac guanine nucleotide exchange factor 2. (909 aa)
	BRINP2	BMP/retinoic acid inducible neural specific 2. (783 aa)
	M3Y193_MUSPF	C2 domain-containing protein. (500 aa)
	FOXG1	Forkhead box G1. (424 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	IMPACT	Impact RWD domain protein. (318 aa)
	BMP2	Bone morphogenetic protein 2. (395 aa)
	M3Y503_MUSPF	Homeobox domain-containing protein. (149 aa)
	CDON	Cell adhesion associated, oncogene regulated. (1260 aa)
	FEZF1	FEZ family zinc finger 1. (475 aa)
	SOCS2	Suppressor of cytokine signaling 2. (198 aa)
	BRINP1	BMP/retinoic acid inducible neural specific 1. (761 aa)
	VWC2L	Von Willebrand factor C domain containing 2 like. (222 aa)
	MEF2C	Myocyte enhancer factor 2C. (433 aa)
	PCP4	Purkinje cell protein 4. (62 aa)
	GDPD5	Glycerophosphodiester phosphodiesterase domain containing 5. (605 aa)
	NKX6-1	NK6 homeobox 1. (355 aa)
	ZC4H2	Zinc finger C4H2-type containing. (224 aa)
	DUOXA1	Dual oxidase maturation factor 1. (430 aa)
	CYB5D2	Cytochrome b5 domain containing 2; Belongs to the cytochrome b5 family. (244 aa)
	NKX2-5	NK2 homeobox 5. (323 aa)
	ZEB1	Zinc finger E-box binding homeobox 1. (1109 aa)
	PROX1	Prospero homeobox 1. (737 aa)
	GDF7	Growth differentiation factor 7. (382 aa)
	HOXD3	Homeobox D3. (430 aa)
	MMD	Monocyte to macrophage differentiation associated. (238 aa)
	SPAG9	Sperm associated antigen 9. (1320 aa)
	FOXA1	Forkhead box A1. (501 aa)
	TCF4	Transcription factor 4. (708 aa)
	MMD2	Monocyte to macrophage differentiation associated 2. (246 aa)
	FEZF2	FEZ family zinc finger 2. (460 aa)
	ECT2	Epithelial cell transforming 2. (914 aa)
	SIN3A	SIN3 transcription regulator family member A. (1550 aa)
	FGF2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
	M3Z266_MUSPF	C2 domain-containing protein. (537 aa)
	VWC2	Von Willebrand factor C domain containing 2. (275 aa)
	ADRA2B	Adrenoceptor alpha 2B. (446 aa)
	TRIM32	Tripartite motif containing 32. (673 aa)
	ATOH1	Atonal bHLH transcription factor 1. (359 aa)
	NEUROG1	Neurogenin 1. (247 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATOH1	FOXG1	ENSMPUP00000018969	ENSMPUP00000005386	Atonal bHLH transcription factor 1.	Forkhead box G1.	0.524
ATOH1	M3Y503_MUSPF	ENSMPUP00000018969	ENSMPUP00000006404	Atonal bHLH transcription factor 1.	Homeobox domain-containing protein.	0.499
ATOH1	TCF4	ENSMPUP00000018969	ENSMPUP00000016357	Atonal bHLH transcription factor 1.	Transcription factor 4.	0.608
BCL6	SIN3A	ENSMPUP00000003385	ENSMPUP00000017213	BCL6 transcription repressor.	SIN3 transcription regulator family member A.	0.610
BMP2	BMP4	ENSMPUP00000006323	ENSMPUP00000005423	Bone morphogenetic protein 2.	Bone morphogenetic protein 4.	0.935
BMP2	BMP6	ENSMPUP00000006323	ENSMPUP00000000577	Bone morphogenetic protein 2.	Bone morphogenetic protein 6.	0.955
BMP2	FGF2	ENSMPUP00000006323	ENSMPUP00000017277	Bone morphogenetic protein 2.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.728
BMP4	BMP2	ENSMPUP00000005423	ENSMPUP00000006323	Bone morphogenetic protein 4.	Bone morphogenetic protein 2.	0.935
BMP4	BMP6	ENSMPUP00000005423	ENSMPUP00000000577	Bone morphogenetic protein 4.	Bone morphogenetic protein 6.	0.965
BMP4	FGF2	ENSMPUP00000005423	ENSMPUP00000017277	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.782
BMP4	NKX2-5	ENSMPUP00000005423	ENSMPUP00000012613	Bone morphogenetic protein 4.	NK2 homeobox 5.	0.436
BMP6	BMP2	ENSMPUP00000000577	ENSMPUP00000006323	Bone morphogenetic protein 6.	Bone morphogenetic protein 2.	0.955
BMP6	BMP4	ENSMPUP00000000577	ENSMPUP00000005423	Bone morphogenetic protein 6.	Bone morphogenetic protein 4.	0.965
BMP6	FGF2	ENSMPUP00000000577	ENSMPUP00000017277	Bone morphogenetic protein 6.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.515
BMP6	GDF7	ENSMPUP00000000577	ENSMPUP00000013639	Bone morphogenetic protein 6.	Growth differentiation factor 7.	0.560
CDON	MEF2C	ENSMPUP00000006536	ENSMPUP00000007906	Cell adhesion associated, oncogene regulated.	Myocyte enhancer factor 2C.	0.484
CDON	SPAG9	ENSMPUP00000006536	ENSMPUP00000015444	Cell adhesion associated, oncogene regulated.	Sperm associated antigen 9.	0.696
DLX1	DLX2	ENSMPUP00000000833	ENSMPUP00000000835	Distal-less homeobox 1.	Distal-less homeobox 2.	0.757
DLX1	FEZF2	ENSMPUP00000000833	ENSMPUP00000016812	Distal-less homeobox 1.	FEZ family zinc finger 2.	0.448
DLX1	FOXG1	ENSMPUP00000000833	ENSMPUP00000005386	Distal-less homeobox 1.	Forkhead box G1.	0.498