STRINGSTRING
TGFB1 TGFB1 TENT5A TENT5A M3Z6K8_MUSPF M3Z6K8_MUSPF TOB2 TOB2 LOC106003358 LOC106003358 CCN1 CCN1 BMP4 BMP4 ANO6 ANO6 BMPR2 BMPR2 BMP2 BMP2 SLC8A3 SLC8A3 ATP2B1 ATP2B1 MEF2C MEF2C BMPR1A BMPR1A SLC8A1 SLC8A1 PKDCC PKDCC ALOX5 ALOX5 SCUBE2 SCUBE2 PTH PTH OSR1 OSR1 ISG15 ISG15 WNT10B WNT10B BMP6 BMP6 TFAP2A TFAP2A BMPR1B BMPR1B P2RX7 P2RX7 PTPN11 PTPN11 ACVR2B ACVR2B ACTN3 ACTN3 NIPBL NIPBL TMEM119 TMEM119 ACVR2A ACVR2A ZBTB16 ZBTB16 PTN PTN TGFB2 TGFB2 LTF LTF OSR2 OSR2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TGFB1Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa)
TENT5ATerminal nucleotidyltransferase 5A. (446 aa)
M3Z6K8_MUSPFG_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor Fz/Smo family. (397 aa)
TOB2Transducer of ERBB2, 2. (339 aa)
LOC106003358Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (544 aa)
CCN1Cellular communication network factor 1. (382 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
ANO6Anoctamin. (911 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1045 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (927 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1220 aa)
MEF2CMyocyte enhancer factor 2C. (433 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (533 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (839 aa)
PKDCCProtein kinase domain containing, cytoplasmic. (294 aa)
ALOX5Arachidonate 5-lipoxygenase. (674 aa)
SCUBE2Signal peptide, CUB domain and EGF like domain containing 2. (992 aa)
PTHParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (115 aa)
OSR1Odd-skipped related transcription factor 1. (267 aa)
ISG15ISG15 ubiquitin like modifier. (184 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
BMP6Bone morphogenetic protein 6. (426 aa)
TFAP2ATranscription factor AP-2 alpha. (384 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (514 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (594 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (484 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (904 aa)
NIPBLNipped-B protein. (2803 aa)
TMEM119Transmembrane protein 119. (254 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
ZBTB16Zinc finger and BTB domain containing 16. (673 aa)
PTNPleiotrophin. (168 aa)
TGFB2Transforming growth factor beta-2 proprotein; Transforming growth factor beta-2 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively. Transforming growth factor beta-2: Multifunctional protein that regulates various processes such as angiogenesis and heart development (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transfor [...] (414 aa)
LTFLactotransferrin; Belongs to the transferrin family. (711 aa)
OSR2Odd-skipped related transciption factor 2. (276 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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