STRINGSTRING
TOM1L2 TOM1L2 TRIM75P TRIM75P M3Z8M5_MUSPF M3Z8M5_MUSPF TREX1 TREX1 M3Z7E4_MUSPF M3Z7E4_MUSPF ZNF830 ZNF830 M3Z614_MUSPF M3Z614_MUSPF TRIM60 TRIM60 M3Z4Z5_MUSPF M3Z4Z5_MUSPF HASPIN HASPIN RINT1 RINT1 HUS1 HUS1 INHBA INHBA TTK TTK BABAM2 BABAM2 MAD1L1 MAD1L1 RBL1 RBL1 MDM2 MDM2 E2F7 E2F7 MAD2L1 MAD2L1 JADE1 JADE1 TPRA1 TPRA1 PML PML M3Z0N7_MUSPF M3Z0N7_MUSPF FANCD2 FANCD2 CTDSP1 CTDSP1 MIIP MIIP PHKG1 PHKG1 BRCC3 BRCC3 BABAM1 BABAM1 DTL DTL M3YWI4_MUSPF M3YWI4_MUSPF M3YWI3_MUSPF M3YWI3_MUSPF TICRR TICRR BLM BLM EME2 EME2 EME1 EME1 TOM1L1 TOM1L1 CDK5RAP3 CDK5RAP3 WAC WAC NME6 NME6 HECA HECA CDC6 CDC6 NLE1 NLE1 CLSPN CLSPN ZNF207 ZNF207 ABRAXAS1 ABRAXAS1 CRLF3 CRLF3 RAD17 RAD17 CDKN1A CDKN1A SLC9A3R1 SLC9A3R1 ATF2 ATF2 DCUN1D3 DCUN1D3 CHEK2 CHEK2 GPNMB GPNMB ANGEL2 ANGEL2 MFSD11 MFSD11 AFMID AFMID BIRC5 BIRC5 SPDL1 SPDL1 USP47 USP47 NABP1 NABP1 APC APC ABL1 ABL1 STK33 STK33 FBXO7 FBXO7 UIMC1 UIMC1 MRE11 MRE11 PLK1 PLK1 TPR TPR TRIM39 TRIM39 CDKN1B CDKN1B NACC2 NACC2 IER3 IER3 OVOL1 OVOL1 ZFP36L2 ZFP36L2 BTG2 BTG2 CTNNB1 CTNNB1 MUS81 MUS81 TNF TNF MYO16 MYO16 CDK1 CDK1 MSH2 MSH2 NBN NBN BTG3 BTG3 FBXO5 FBXO5 TRIP13 TRIP13 M3YF83_MUSPF M3YF83_MUSPF RFWD3 RFWD3 M3YEV5_MUSPF M3YEV5_MUSPF TOPBP1 TOPBP1 M3YD28_MUSPF M3YD28_MUSPF MEIOC MEIOC PIDD1 PIDD1 TP53 TP53 LRRC1 LRRC1 ZFYVE19 ZFYVE19 FBXO31 FBXO31 M3YAG0_MUSPF M3YAG0_MUSPF INTS3 INTS3 FOXN3 FOXN3 AURKB AURKB SCRIB SCRIB DLG2 DLG2 M3Y9H7_MUSPF M3Y9H7_MUSPF BRINP1 BRINP1 M3Y878_MUSPF M3Y878_MUSPF BTG1 BTG1 PTPN3 PTPN3 M3Y7C1_MUSPF M3Y7C1_MUSPF ZFP36L1 ZFP36L1 EZH2 EZH2 CASP2 CASP2 ORC1 ORC1 CHEK1 CHEK1 BMP7 BMP7 DACT1 DACT1 ATM ATM KANK2 KANK2 MUC1 MUC1 BMP4 BMP4 NAE1 NAE1 BRINP2 BRINP2 CDC73 CDC73 FOXO4 FOXO4 CCND1 CCND1 SDE2 SDE2 BRINP3 BRINP3 NOP53 NOP53 PSMG2 PSMG2 ZW10 ZW10 FZR1 FZR1 RAD9A RAD9A DLG1 DLG1 KLHL22 KLHL22 BTG4 BTG4 RBL2 RBL2 BRD7 BRD7 CTDSPL CTDSPL TAOK3 TAOK3 BUB3 BUB3 CHFR CHFR C10orf90 C10orf90 PKD2 PKD2 RAD9B RAD9B CTDSP2 CTDSP2 M3XSB1_MUSPF M3XSB1_MUSPF LOC101688276 LOC101688276 KNTC1 KNTC1 CHMP4C CHMP4C M3XRQ6_MUSPF M3XRQ6_MUSPF RB1 RB1 M3XQD6_MUSPF M3XQD6_MUSPF DONSON DONSON MTBP MTBP PRKDC PRKDC RAD21 RAD21 FZD3 FZD3 TRIM35 TRIM35 MRNIP MRNIP TIPIN TIPIN ZWILCH ZWILCH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TOM1L2Target of myb1 like 2 membrane trafficking protein; Belongs to the TOM1 family. (506 aa)
TRIM75PTripartite motif containing 75, pseudogene. (485 aa)
M3Z8M5_MUSPFUncharacterized protein. (211 aa)
TREX1Three prime repair exonuclease 1. (313 aa)
M3Z7E4_MUSPFUncharacterized protein. (1085 aa)
ZNF830Zinc finger protein 830. (369 aa)
M3Z614_MUSPFG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (386 aa)
TRIM60Tripartite motif containing 60. (466 aa)
M3Z4Z5_MUSPFUncharacterized protein. (472 aa)
HASPINHistone H3 associated protein kinase. (767 aa)
RINT1RAD50 interactor 1. (792 aa)
HUS1Checkpoint protein; Belongs to the HUS1 family. (280 aa)
INHBAInhibin subunit beta A. (424 aa)
TTKTTK protein kinase. (856 aa)
BABAM2BRISC and BRCA1 A complex member 2. (383 aa)
MAD1L1Mitotic arrest deficient 1 like 1. (737 aa)
RBL1RB transcriptional corepressor like 1. (1066 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (487 aa)
E2F7E2F transcription factor 7. (899 aa)
MAD2L1Mitotic arrest deficient 2 like 1. (205 aa)
JADE1Jade family PHD finger 1. (842 aa)
TPRA1Transmembrane protein adipocyte associated 1. (365 aa)
PMLPromyelocytic leukemia. (876 aa)
M3Z0N7_MUSPFUncharacterized protein. (978 aa)
FANCD2FA complementation group D2. (1275 aa)
CTDSP1CTD small phosphatase 1. (261 aa)
MIIPMigration and invasion inhibitory protein. (378 aa)
PHKG1Phosphorylase kinase catalytic subunit gamma 1; Belongs to the protein kinase superfamily. (387 aa)
BRCC3BRCA1/BRCA2-containing complex subunit 3. (316 aa)
BABAM1BRISC and BRCA1 A complex member 1. (336 aa)
DTLDenticleless E3 ubiquitin protein ligase homolog. (730 aa)
M3YWI4_MUSPFUncharacterized protein. (246 aa)
M3YWI3_MUSPFUncharacterized protein. (246 aa)
TICRRTOPBP1 interacting checkpoint and replication regulator. (1705 aa)
BLMBLM RecQ like helicase. (1221 aa)
EME2Essential meiotic structure-specific endonuclease subunit 2. (387 aa)
EME1Essential meiotic structure-specific endonuclease 1. (573 aa)
TOM1L1Target of myb1 like 1 membrane trafficking protein; Belongs to the TOM1 family. (476 aa)
CDK5RAP3CDK5 regulatory subunit associated protein 3. (504 aa)
WACWW domain containing adaptor with coiled-coil. (601 aa)
NME6Nucleoside diphosphate kinase. (226 aa)
HECAHdc homolog, cell cycle regulator. (455 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (558 aa)
NLE1Notchless homolog 1. (485 aa)
CLSPNClaspin. (1336 aa)
ZNF207Zinc finger protein 207. (534 aa)
ABRAXAS1Abraxas 1, BRCA1 A complex subunit. (360 aa)
CRLF3Cytokine receptor like factor 3. (441 aa)
RAD17RAD17 checkpoint clamp loader component. (680 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (164 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (366 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
DCUN1D3DCN1-like protein. (304 aa)
CHEK2Checkpoint kinase 2. (544 aa)
GPNMBGlycoprotein nmb. (555 aa)
ANGEL2Angel homolog 2. (544 aa)
MFSD11Major facilitator superfamily domain containing 11. (449 aa)
AFMIDKynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. (307 aa)
BIRC5Baculoviral IAP repeat containing 5. (142 aa)
SPDL1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. (603 aa)
USP47Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1361 aa)
NABP1Nucleic acid binding protein 1. (173 aa)
APCAPC regulator of WNT signaling pathway. (2862 aa)
ABL1Tyrosine-protein kinase. (1150 aa)
STK33Serine/threonine kinase 33; Belongs to the protein kinase superfamily. (489 aa)
FBXO7F-box protein 7. (444 aa)
UIMC1Ubiquitin interaction motif containing 1. (644 aa)
MRE11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (707 aa)
PLK1Serine/threonine-protein kinase PLK. (542 aa)
TPRTranslocated promoter region, nuclear basket protein. (2439 aa)
TRIM39Tripartite motif containing 39. (488 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (199 aa)
NACC2NACC family member 2. (636 aa)
IER3Immediate early response 3. (155 aa)
OVOL1Ovo like transcriptional repressor 1. (267 aa)
ZFP36L2ZFP36 ring finger protein like 2. (495 aa)
BTG2BTG anti-proliferation factor 2. (162 aa)
CTNNB1Catenin beta 1. (781 aa)
MUS81MUS81 structure-specific endonuclease subunit. (546 aa)
TNFTumor necrosis factor alpha; Belongs to the tumor necrosis factor family. (233 aa)
MYO16Myosin XVI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1789 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
MSH2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa)
NBNNibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (749 aa)
BTG3Uncharacterized protein. (252 aa)
FBXO5F-box protein 5. (386 aa)
TRIP13Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (434 aa)
M3YF83_MUSPFProtein kinase domain-containing protein. (378 aa)
RFWD3Ring finger and WD repeat domain 3. (772 aa)
M3YEV5_MUSPFAnti_prolifrtn domain-containing protein. (243 aa)
TOPBP1DNA topoisomerase II binding protein 1. (1466 aa)
M3YD28_MUSPFUncharacterized protein. (1086 aa)
MEIOCMeiosis specific with coiled-coil domain. (960 aa)
PIDD1P53-induced death domain protein 1. (915 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (375 aa)
LRRC1Leucine rich repeat containing 1. (524 aa)
ZFYVE19Zinc finger FYVE-type containing 19. (399 aa)
FBXO31F-box protein 31. (421 aa)
M3YAG0_MUSPFBUB1 N-terminal domain-containing protein. (1062 aa)
INTS3Integrator complex subunit 3. (987 aa)
FOXN3Forkhead box N3. (515 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (344 aa)
SCRIBScribble planar cell polarity protein. (1523 aa)
DLG2Uncharacterized protein. (833 aa)
M3Y9H7_MUSPFUncharacterized protein. (205 aa)
BRINP1BMP/retinoic acid inducible neural specific 1. (761 aa)
M3Y878_MUSPFUncharacterized protein. (67 aa)
BTG1BTG anti-proliferation factor 1. (171 aa)
PTPN3Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (994 aa)
M3Y7C1_MUSPFUncharacterized protein; Belongs to the AAA ATPase family. (437 aa)
ZFP36L1ZFP36 ring finger protein like 1. (317 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (753 aa)
CASP2Caspase 2; Belongs to the peptidase C14A family. (452 aa)
ORC1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (862 aa)
CHEK1Checkpoint kinase 1; Belongs to the protein kinase superfamily. (476 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
DACT1Dishevelled binding antagonist of beta catenin 1. (759 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3057 aa)
KANK2KN motif and ankyrin repeat domains 2. (851 aa)
MUC1SEA domain-containing protein. (560 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
NAE1NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. (597 aa)
BRINP2BMP/retinoic acid inducible neural specific 2. (783 aa)
CDC73Cell division cycle 73. (531 aa)
FOXO4Forkhead box O4. (509 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
SDE2SDE2 telomere maintenance homolog. (490 aa)
BRINP3BMP/retinoic acid inducible neural specific 3. (766 aa)
NOP53NOP53 ribosome biogenesis factor. (486 aa)
PSMG2Proteasome assembly chaperone 2; Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. Belongs to the PSMG2 family. (264 aa)
ZW10Zw10 kinetochore protein. (779 aa)
FZR1Fizzy and cell division cycle 20 related 1. (493 aa)
RAD9ACell cycle checkpoint control protein; Belongs to the rad9 family. (385 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (927 aa)
KLHL22Kelch like family member 22. (634 aa)
BTG4BTG anti-proliferation factor 4. (230 aa)
RBL2RB transcriptional corepressor like 2. (1139 aa)
BRD7Bromodomain containing 7. (651 aa)
CTDSPLCTD small phosphatase like. (208 aa)
TAOK3TAO kinase 3. (914 aa)
BUB3BUB3 mitotic checkpoint protein. (328 aa)
CHFRCheckpoint with forkhead and ring finger domains. (632 aa)
C10orf90Chromosome 10 open reading frame 90. (687 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (915 aa)
RAD9BCell cycle checkpoint control protein; Belongs to the rad9 family. (424 aa)
CTDSP2CTD small phosphatase 2. (271 aa)
M3XSB1_MUSPFUncharacterized protein. (296 aa)
LOC101688276Uncharacterized protein. (479 aa)
KNTC1Kinetochore associated 1. (2207 aa)
CHMP4CCharged multivesicular body protein 4C. (237 aa)
M3XRQ6_MUSPFG-patch domain-containing protein. (319 aa)
RB1RB transcriptional corepressor 1. (948 aa)
M3XQD6_MUSPFOB domain-containing protein. (211 aa)
DONSONDownstream neighbor of SON. (470 aa)
MTBPMDM2 binding protein. (893 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4110 aa)
RAD21RAD21 cohesin complex component. (631 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
TRIM35Tripartite motif containing 35. (493 aa)
MRNIPMRN complex interacting protein. (339 aa)
TIPINTIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (293 aa)
ZWILCHZwilch kinetochore protein. (589 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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