(12 nodes) Positive regulation of steroid metabolic process network (Mustela putorius)

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Your Input:
	IGF2	Insulin like growth factor 2. (192 aa)
	APOA1	Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family. (323 aa)
	BMP6	Bone morphogenetic protein 6. (426 aa)
	ABCG4	ATP binding cassette subfamily G member 4. (646 aa)
	STARD4	StAR related lipid transfer domain containing 4. (179 aa)
	SREBF1	Sterol regulatory element binding transcription factor 1. (1147 aa)
	TNF	Tumor necrosis factor alpha; Belongs to the tumor necrosis factor family. (233 aa)
	CGA	Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (120 aa)
	FGF1	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
	NR1D1	Nuclear receptor subfamily 1 group D member 1. (613 aa)
	SCAP	SREBF chaperone. (1278 aa)
	IFNG	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity). (166 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IFNG	TNF	ENSMPUP00000017401	ENSMPUP00000011297	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity).	Tumor necrosis factor alpha; Belongs to the tumor necrosis factor family.	0.868
SCAP	SREBF1	ENSMPUP00000014908	ENSMPUP00000000024	SREBF chaperone.	Sterol regulatory element binding transcription factor 1.	0.979
SREBF1	SCAP	ENSMPUP00000000024	ENSMPUP00000014908	Sterol regulatory element binding transcription factor 1.	SREBF chaperone.	0.979
TNF	IFNG	ENSMPUP00000011297	ENSMPUP00000017401	Tumor necrosis factor alpha; Belongs to the tumor necrosis factor family.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity).	0.868