(19 nodes) Positive regulation of natural killer cell mediated cytotoxicity network (Mustela putorius)

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	M3XNH8_MUSPF	Uncharacterized protein. (132 aa)
	SH2D1A	SH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2. (124 aa)
	CADM1	Cell adhesion molecule 1. (427 aa)
	CRTAM	Cytotoxic and regulatory T cell molecule. (393 aa)
	PVR	Uncharacterized protein. (391 aa)
	KLRD1	Killer cell lectin like receptor D1. (179 aa)
	KLRK1	Killer cell lectin like receptor K1. (191 aa)
	VAV1	Vav guanine nucleotide exchange factor 1. (845 aa)
	AP1G1	AP-1 complex subunit gamma. (814 aa)
	M3YA49_MUSPF	Uncharacterized protein. (659 aa)
	M3YA60_MUSPF	N-terminal Ras-GEF domain-containing protein. (178 aa)
	LAMP1	Lysosomal associated membrane protein 1. (388 aa)
	STAT5B	Signal transducer and activator of transcription. (691 aa)
	NCR3	Natural cytotoxicity triggering receptor 3. (201 aa)
	IL18RAP	Interleukin 18 receptor accessory protein. (581 aa)
	M3YRQ6_MUSPF	Ig-like domain-containing protein. (336 aa)
	CD226	CD226 molecule. (336 aa)
	LAG3	Lymphocyte activating 3. (521 aa)
	IL21	Interleukin; Belongs to the IL-15/IL-21 family. (153 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CADM1	CRTAM	ENSMPUP00000003987	ENSMPUP00000005746	Cell adhesion molecule 1.	Cytotoxic and regulatory T cell molecule.	0.663
CD226	PVR	ENSMPUP00000016500	ENSMPUP00000006349	CD226 molecule.	Uncharacterized protein.	0.960
CRTAM	CADM1	ENSMPUP00000005746	ENSMPUP00000003987	Cytotoxic and regulatory T cell molecule.	Cell adhesion molecule 1.	0.663
CRTAM	KLRD1	ENSMPUP00000005746	ENSMPUP00000006423	Cytotoxic and regulatory T cell molecule.	Killer cell lectin like receptor D1.	0.421
CRTAM	M3YRQ6_MUSPF	ENSMPUP00000005746	ENSMPUP00000014016	Cytotoxic and regulatory T cell molecule.	Ig-like domain-containing protein.	0.410
IL21	STAT5B	ENSMPUP00000017281	ENSMPUP00000010450	Interleukin; Belongs to the IL-15/IL-21 family.	Signal transducer and activator of transcription.	0.697
KLRD1	CRTAM	ENSMPUP00000006423	ENSMPUP00000005746	Killer cell lectin like receptor D1.	Cytotoxic and regulatory T cell molecule.	0.421
KLRD1	KLRK1	ENSMPUP00000006423	ENSMPUP00000006450	Killer cell lectin like receptor D1.	Killer cell lectin like receptor K1.	0.598
KLRD1	LAG3	ENSMPUP00000006423	ENSMPUP00000016720	Killer cell lectin like receptor D1.	Lymphocyte activating 3.	0.433
KLRD1	LAMP1	ENSMPUP00000006423	ENSMPUP00000009873	Killer cell lectin like receptor D1.	Lysosomal associated membrane protein 1.	0.464
KLRD1	M3XNH8_MUSPF	ENSMPUP00000006423	ENSMPUP00000000628	Killer cell lectin like receptor D1.	Uncharacterized protein.	0.502
KLRK1	KLRD1	ENSMPUP00000006450	ENSMPUP00000006423	Killer cell lectin like receptor K1.	Killer cell lectin like receptor D1.	0.598
LAG3	KLRD1	ENSMPUP00000016720	ENSMPUP00000006423	Lymphocyte activating 3.	Killer cell lectin like receptor D1.	0.433
LAG3	LAMP1	ENSMPUP00000016720	ENSMPUP00000009873	Lymphocyte activating 3.	Lysosomal associated membrane protein 1.	0.410
LAMP1	KLRD1	ENSMPUP00000009873	ENSMPUP00000006423	Lysosomal associated membrane protein 1.	Killer cell lectin like receptor D1.	0.464
LAMP1	LAG3	ENSMPUP00000009873	ENSMPUP00000016720	Lysosomal associated membrane protein 1.	Lymphocyte activating 3.	0.410
M3XNH8_MUSPF	KLRD1	ENSMPUP00000000628	ENSMPUP00000006423	Uncharacterized protein.	Killer cell lectin like receptor D1.	0.502
M3YA49_MUSPF	M3YA60_MUSPF	ENSMPUP00000008206	ENSMPUP00000008217	Uncharacterized protein.	N-terminal Ras-GEF domain-containing protein.	0.899
M3YA60_MUSPF	M3YA49_MUSPF	ENSMPUP00000008217	ENSMPUP00000008206	N-terminal Ras-GEF domain-containing protein.	Uncharacterized protein.	0.899
M3YRQ6_MUSPF	CRTAM	ENSMPUP00000014016	ENSMPUP00000005746	Ig-like domain-containing protein.	Cytotoxic and regulatory T cell molecule.	0.410