STRINGSTRING
MAP3K10 MAP3K10 EGFR EGFR ITCH ITCH M3XM17_MUSPF M3XM17_MUSPF RIPK1 RIPK1 FLT4 FLT4 TNFRSF19 TNFRSF19 M3XP26_MUSPF M3XP26_MUSPF PTK2B PTK2B XIAP XIAP TLR4 TLR4 TNFSF11 TNFSF11 MAPK8IP2 MAPK8IP2 NOX1 NOX1 PRMT1 PRMT1 TRAF3 TRAF3 MYD88 MYD88 TAOK3 TAOK3 NOD2 NOD2 CYLD CYLD HIPK2 HIPK2 TRPV4 TRPV4 DUSP10 DUSP10 CCL19 CCL19 CCL21 CCL21 M3XZP3_MUSPF M3XZP3_MUSPF FGF19 FGF19 NOD1 NOD1 MAGI3 MAGI3 SFRP2 SFRP2 F2RL1 F2RL1 MAPK8IP1 MAPK8IP1 M3Y377_MUSPF M3Y377_MUSPF DACT1 DACT1 PLCB1 PLCB1 GADD45B GADD45B MMP8 MMP8 WNT16 WNT16 RB1CC1 RB1CC1 FKTN FKTN MDFIC MDFIC DAB2IP DAB2IP SH3RF1 SH3RF1 TRAF1 TRAF1 SH3RF2 SH3RF2 MARVELD3 MARVELD3 BIRC7 BIRC7 HDAC3 HDAC3 M3YA49_MUSPF M3YA49_MUSPF M3YA60_MUSPF M3YA60_MUSPF RASSF2 RASSF2 KLHL31 KLHL31 ANKRD6 ANKRD6 CRACR2A CRACR2A M3YE25_MUSPF M3YE25_MUSPF AGER AGER M3YFJ1_MUSPF M3YFJ1_MUSPF NCOR1 NCOR1 SH3RF3 SH3RF3 EDAR EDAR IGF1R IGF1R RIPK2 RIPK2 TRAF2 TRAF2 RETREG1 RETREG1 ZNF622 ZNF622 TLR3 TLR3 TNF TNF MFHAS1 MFHAS1 PYCARD PYCARD CARD9 CARD9 ULK4 ULK4 DUSP16 DUSP16 TRAF6 TRAF6 MAP3K11 MAP3K11 MAP4K2 MAP4K2 PJA2 PJA2 PAFAH1B1 PAFAH1B1 SERPINF2 SERPINF2 UNC5CL UNC5CL TRAF4 TRAF4 M3YRT8_MUSPF M3YRT8_MUSPF RAB44 RAB44 TPD52L1 TPD52L1 CCN2 CCN2 MAP3K5 MAP3K5 M3YUJ9_MUSPF M3YUJ9_MUSPF STK3 STK3 TRAF5 TRAF5 AXIN1 AXIN1 NCF1 NCF1 M3YXK6_MUSPF M3YXK6_MUSPF ZMYND11 ZMYND11 WNT7B WNT7B MBIP MBIP M3YYK0_MUSPF M3YYK0_MUSPF M3YYK2_MUSPF M3YYK2_MUSPF CD27 CD27 LTBR LTBR MECOM MECOM WNT7A WNT7A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAP3K10Mitogen-activated protein kinase kinase kinase. (936 aa)
EGFRReceptor protein-tyrosine kinase. (1207 aa)
ITCHE3 ubiquitin-protein ligase. (880 aa)
M3XM17_MUSPFUncharacterized protein. (208 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (646 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1355 aa)
TNFRSF19TNF receptor superfamily member 19. (444 aa)
M3XP26_MUSPFUncharacterized protein. (265 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
XIAPX-linked inhibitor of apoptosis. (497 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (833 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (321 aa)
MAPK8IP2Mitogen-activated protein kinase 8 interacting protein 2. (832 aa)
NOX1NADPH oxidase 1. (589 aa)
PRMT1Protein arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (374 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (569 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
TAOK3TAO kinase 3. (914 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1013 aa)
CYLDCYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (953 aa)
HIPK2Homeodomain interacting protein kinase 2. (1165 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (873 aa)
DUSP10Dual specificity phosphatase 10. (482 aa)
CCL19C-C motif chemokine. (108 aa)
CCL21SCY domain-containing protein. (137 aa)
M3XZP3_MUSPFHMG box domain-containing protein. (215 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (219 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (952 aa)
MAGI3Membrane associated guanylate kinase, WW and PDZ domain containing 3. (1466 aa)
SFRP2Secreted frizzled related protein 2. (294 aa)
F2RL1F2R like trypsin receptor 1. (397 aa)
MAPK8IP1Mitogen-activated protein kinase 8 interacting protein 1. (703 aa)
M3Y377_MUSPFNTR domain-containing protein. (233 aa)
DACT1Dishevelled binding antagonist of beta catenin 1. (759 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1096 aa)
GADD45BGrowth arrest and DNA damage inducible beta. (160 aa)
MMP8Matrix metallopeptidase 8. (473 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa)
RB1CC1RB1 inducible coiled-coil 1. (1593 aa)
FKTNFukutin. (436 aa)
MDFICMyoD family inhibitor domain containing. (243 aa)
DAB2IPDAB2 interacting protein. (1112 aa)
SH3RF1SH3 domain containing ring finger 1. (880 aa)
TRAF1TNF receptor-associated factor. (415 aa)
SH3RF2SH3 domain containing ring finger 2. (733 aa)
MARVELD3MARVEL domain containing 3. (385 aa)
BIRC7Baculoviral IAP repeat containing 7. (300 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (430 aa)
M3YA49_MUSPFUncharacterized protein. (659 aa)
M3YA60_MUSPFN-terminal Ras-GEF domain-containing protein. (178 aa)
RASSF2Ras association domain family member 2. (326 aa)
KLHL31Kelch like family member 31. (646 aa)
ANKRD6Ankyrin repeat domain 6. (727 aa)
CRACR2ACalcium release activated channel regulator 2A. (709 aa)
M3YE25_MUSPFDual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (153 aa)
AGERAdvanced glycosylation end-product specific receptor. (400 aa)
M3YFJ1_MUSPFMPN domain-containing protein. (331 aa)
NCOR1Nuclear receptor corepressor 1. (2510 aa)
SH3RF3SH3 domain containing ring finger 3. (695 aa)
EDAREctodysplasin A receptor. (459 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (569 aa)
RETREG1Reticulophagy regulator 1. (362 aa)
ZNF622Zinc finger protein 622. (475 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (764 aa)
TNFTumor necrosis factor alpha; Belongs to the tumor necrosis factor family. (233 aa)
MFHAS1Malignant fibrous histiocytoma amplified sequence 1. (1052 aa)
PYCARDPYD and CARD domain containing. (193 aa)
CARD9Caspase recruitment domain family member 9. (478 aa)
ULK4Unc-51 like kinase 4. (1274 aa)
DUSP16Dual specificity phosphatase 16. (663 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
MAP3K11Mitogen-activated protein kinase kinase kinase. (863 aa)
MAP4K2Mitogen-activated protein kinase kinase kinase kinase 2; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (847 aa)
PJA2Praja ring finger ubiquitin ligase 2. (710 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
SERPINF2Serpin family F member 2; Belongs to the serpin family. (491 aa)
UNC5CLUnc-5 family C-terminal like. (550 aa)
TRAF4TNF receptor-associated factor. (470 aa)
M3YRT8_MUSPFIg-like domain-containing protein. (339 aa)
RAB44Uncharacterized protein. (245 aa)
TPD52L1TPD52 like 1. (209 aa)
CCN2Cellular communication network factor 2. (349 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1398 aa)
M3YUJ9_MUSPFHMG box domain-containing protein. (171 aa)
STK3Serine/threonine kinase 3. (418 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (558 aa)
AXIN1Axin 1. (862 aa)
NCF1Neutrophil cytosolic factor 1. (391 aa)
M3YXK6_MUSPFMPN domain-containing protein. (143 aa)
ZMYND11Zinc finger MYND-type containing 11. (636 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
MBIPMAP3K12 binding inhibitory protein 1. (344 aa)
M3YYK0_MUSPFPH domain-containing protein. (490 aa)
M3YYK2_MUSPFPPM-type phosphatase domain-containing protein. (257 aa)
CD27CD27 molecule. (263 aa)
LTBRLymphotoxin beta receptor. (420 aa)
MECOMMDS1 and EVI1 complex locus. (1212 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.