STRINGSTRING
CDK16 CDK16 PLA2G6 PLA2G6 PICK1 PICK1 LRRC8A LRRC8A BAD BAD PLA2G3 PLA2G3 C1QTNF6 C1QTNF6 M3YLM3_MUSPF M3YLM3_MUSPF C1QTNF1 C1QTNF1 CRY1 CRY1 PRKCE PRKCE NR1H4 NR1H4 TNF TNF KDM5B KDM5B EFNA5 EFNA5 ARHGEF7 ARHGEF7 TM7SF3 TM7SF3 NKX6-1 NKX6-1 SYT9 SYT9 PFKL PFKL RAB11FIP1 RAB11FIP1 NLGN2 NLGN2 M3YEF8_MUSPF M3YEF8_MUSPF M3YED7_MUSPF M3YED7_MUSPF ALOX5 ALOX5 UCN UCN PAX8 PAX8 SLC9B2 SLC9B2 TFAP2B TFAP2B VAMP8 VAMP8 SLC25A22 SLC25A22 ANXA1 ANXA1 M3YBQ0_MUSPF M3YBQ0_MUSPF SMAD4 SMAD4 HFE HFE MIDN MIDN M3YA21_MUSPF M3YA21_MUSPF M3Y9Z7_MUSPF M3Y9Z7_MUSPF SCG5 SCG5 ABCA12 ABCA12 IL11 IL11 CFTR CFTR HIF1A HIF1A M3Y3R5_MUSPF M3Y3R5_MUSPF M3Y377_MUSPF M3Y377_MUSPF CRY2 CRY2 CRHBP CRHBP ADCYAP1 ADCYAP1 C2CD2L C2CD2L GHRHR GHRHR PDX1 PDX1 SOX4 SOX4 ILDR1 ILDR1 GPLD1 GPLD1 REST REST ANO1 ANO1 M3XZR5_MUSPF M3XZR5_MUSPF M3XZQ7_MUSPF M3XZQ7_MUSPF ADCY5 ADCY5 NPVF NPVF LRP5 LRP5 SIDT2 SIDT2 TCIRG1 TCIRG1 SNX4 SNX4 MCU MCU DRD2 DRD2 CHGA CHGA PPP3CB PPP3CB NKX3-1 NKX3-1 PTPN11 PTPN11 M3XU21_MUSPF M3XU21_MUSPF SLC8B1 SLC8B1 UQCC2 UQCC2 SIRT4 SIRT4 GPR68 GPR68 GPER1 GPER1 KCNJ11 KCNJ11 INHBB INHBB SRI SRI GCK GCK INHBA INHBA SLC25A18 SLC25A18 HMGN3 HMGN3 GHRH GHRH HNF4A HNF4A KCNB1 KCNB1 IFNG IFNG HNF1A HNF1A CAPN10 CAPN10 PASK PASK ACVR1C ACVR1C KLF7 KLF7 CREB1 CREB1 GCG GCG EDN1 EDN1 AACS AACS ADCY8 ADCY8 ICA1 ICA1 TNFSF11 TNFSF11 BLK BLK TCF7L2 TCF7L2 M3XSG3_MUSPF M3XSG3_MUSPF ADRA2A ADRA2A SPP1 SPP1 CHD7 CHD7 M3XTK1_MUSPF M3XTK1_MUSPF HTR2C HTR2C TRH TRH FFAR4 FFAR4 TMF1 TMF1 FAM3D FAM3D CCKAR CCKAR GALR1 GALR1 GRP GRP M3YXE6_MUSPF M3YXE6_MUSPF RAB11FIP3 RAB11FIP3 BAIAP3 BAIAP3 NMB NMB STXBP4 STXBP4 GIP GIP M3YV14_MUSPF M3YV14_MUSPF M3YUN0_MUSPF M3YUN0_MUSPF M3YUE8_MUSPF M3YUE8_MUSPF CCL5 CCL5 NR1D1 NR1D1 RASL10B RASL10B TFAP2E TFAP2E M3YTP8_MUSPF M3YTP8_MUSPF RFX6 RFX6 C1QTNF12 C1QTNF12 POMC POMC FKBP1B FKBP1B RPH3AL RPH3AL DOC2B DOC2B IL6 IL6 BIRC5 BIRC5 LIF LIF OSM OSM
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CDK16Cyclin dependent kinase 16; Belongs to the protein kinase superfamily. (500 aa)
PLA2G6Phospholipase A2 group VI. (806 aa)
PICK1Protein interacting with PRKCA 1. (417 aa)
LRRC8ALeucine rich repeat containing 8 VRAC subunit A. (810 aa)
BADBCL2 associated agonist of cell death. (168 aa)
PLA2G3Phospholipase A2 group III. (510 aa)
C1QTNF6C1q and TNF related 6. (265 aa)
M3YLM3_MUSPFV-SNARE coiled-coil homology domain-containing protein. (496 aa)
C1QTNF1C1q and TNF related 1. (331 aa)
CRY1Cryptochrome circadian regulator 1. (587 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (472 aa)
TNFTumor necrosis factor alpha; Belongs to the tumor necrosis factor family. (233 aa)
KDM5BLysine demethylase 5B. (1691 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (260 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (844 aa)
TM7SF3Transmembrane 7 superfamily member 3. (542 aa)
NKX6-1NK6 homeobox 1. (355 aa)
SYT9Synaptotagmin 9. (491 aa)
PFKLATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (751 aa)
RAB11FIP1RAB11 family interacting protein 1. (1268 aa)
NLGN2Neuroligin 2. (661 aa)
M3YEF8_MUSPFFOXO-TAD domain-containing protein. (399 aa)
M3YED7_MUSPFUncharacterized protein. (135 aa)
ALOX5Arachidonate 5-lipoxygenase. (674 aa)
UCNUrocortin. (126 aa)
PAX8Paired box 8. (462 aa)
SLC9B2Solute carrier family 9 member B2. (538 aa)
TFAP2BTranscription factor AP-2 beta. (476 aa)
VAMP8Vesicle associated membrane protein 8. (111 aa)
SLC25A22Solute carrier family 25 member 22; Belongs to the mitochondrial carrier (TC 2.A.29) family. (323 aa)
ANXA1Annexin. (345 aa)
M3YBQ0_MUSPFSelenoprotein T; Belongs to the SelWTH family. Selenoprotein T subfamily. (137 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
HFEHomeostatic iron regulator; Belongs to the MHC class I family. (403 aa)
MIDNMidnolin. (460 aa)
M3YA21_MUSPFWD_REPEATS_REGION domain-containing protein. (467 aa)
M3Y9Z7_MUSPFLINC02210-CRHR1 readthrough; Belongs to the G-protein coupled receptor 2 family. (342 aa)
SCG5Secretogranin V. (212 aa)
ABCA12ATP binding cassette subfamily A member 12. (2598 aa)
IL11Interleukin 11. (197 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1484 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (824 aa)
M3Y3R5_MUSPFUncharacterized protein. (137 aa)
M3Y377_MUSPFNTR domain-containing protein. (233 aa)
CRY2Cryptochrome circadian regulator 2. (594 aa)
CRHBPCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa)
ADCYAP1Adenylate cyclase activating polypeptide 1. (161 aa)
C2CD2LC2CD2 like. (660 aa)
GHRHRGrowth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (423 aa)
PDX1Pancreatic and duodenal homeobox 1. (283 aa)
SOX4SRY-box transcription factor 4. (269 aa)
ILDR1Immunoglobulin like domain containing receptor 1. (546 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (875 aa)
RESTRE1 silencing transcription factor. (1098 aa)
ANO1Anoctamin. (888 aa)
M3XZR5_MUSPFRBR-type E3 ubiquitin transferase. (115 aa)
M3XZQ7_MUSPFUbiquitin-like domain-containing protein. (311 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1018 aa)
NPVFNeuropeptide VF precursor. (199 aa)
LRP5Uncharacterized protein. (1465 aa)
SIDT2SID1 transmembrane family member 2. (832 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa)
SNX4Sorting nexin 4. (450 aa)
MCUMitochondrial calcium uniporter. (350 aa)
DRD2D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. (443 aa)
CHGAChromogranin A. (448 aa)
PPP3CBSerine/threonine-protein phosphatase. (479 aa)
NKX3-1NK3 homeobox 1. (231 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
M3XU21_MUSPFSelenoprotein T; Belongs to the SelWTH family. Selenoprotein T subfamily. (129 aa)
SLC8B1Solute carrier family 8 member B1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (588 aa)
UQCC2Ubiquinol-cytochrome c reductase complex assembly factor 2. (136 aa)
SIRT4NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (314 aa)
GPR68G protein-coupled receptor 68; Belongs to the G-protein coupled receptor 1 family. (360 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (359 aa)
KCNJ11Potassium voltage-gated channel subfamily J member 11. (390 aa)
INHBBInhibin subunit beta B. (238 aa)
SRISorcin. (198 aa)
GCKPhosphotransferase. (473 aa)
INHBAInhibin subunit beta A. (424 aa)
SLC25A18Solute carrier family 25 member 18; Belongs to the mitochondrial carrier (TC 2.A.29) family. (322 aa)
HMGN3High mobility group nucleosomal binding domain 3. (180 aa)
GHRHGrowth hormone releasing hormone. (104 aa)
HNF4AHepatocyte nuclear factor 4 alpha. (443 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (858 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity). (166 aa)
HNF1AHNF1 homeobox A. (633 aa)
CAPN10Calpain 10; Belongs to the peptidase C2 family. (665 aa)
PASKPAS domain containing serine/threonine kinase. (1341 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
KLF7Kruppel like factor 7. (302 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
GCGGlucagon. (180 aa)
EDN1Endothelin 1. (202 aa)
AACSAcetoacetyl-CoA synthetase. (729 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
ICA1Islet cell autoantigen 1. (510 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (321 aa)
BLKTyrosine-protein kinase. (500 aa)
TCF7L2Transcription factor 7 like 2. (514 aa)
M3XSG3_MUSPFCTNNB1_binding domain-containing protein. (169 aa)
ADRA2AAdrenoceptor alpha 2A; Belongs to the G-protein coupled receptor 1 family. (323 aa)
SPP1Secreted phosphoprotein 1. (272 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2522 aa)
M3XTK1_MUSPFUncharacterized protein. (44 aa)
HTR2C5-hydroxytryptamine receptor 2C. (458 aa)
TRHPro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (246 aa)
FFAR4Free fatty acid receptor 4. (361 aa)
TMF1TATA element modulatory factor 1. (1088 aa)
FAM3DFamily with sequence similarity 3 member D. (223 aa)
CCKARCholecystokinin A receptor; Belongs to the G-protein coupled receptor 1 family. (428 aa)
GALR1Galanin receptor 1; Belongs to the G-protein coupled receptor 1 family. (349 aa)
GRPGastrin releasing peptide. (147 aa)
M3YXE6_MUSPFUncharacterized protein; Belongs to the synaptobrevin family. (220 aa)
RAB11FIP3RAB11 family interacting protein 3. (647 aa)
BAIAP3BAI1 associated protein 3. (1157 aa)
NMBNeuromedin B. (164 aa)
STXBP4Syntaxin binding protein 4. (522 aa)
GIPGastric inhibitory polypeptide. (144 aa)
M3YV14_MUSPFGLUCAGON domain-containing protein. (125 aa)
M3YUN0_MUSPFC1q domain-containing protein. (306 aa)
M3YUE8_MUSPFLongin domain-containing protein; Belongs to the synaptobrevin family. (110 aa)
CCL5C-C motif chemokine. (91 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (613 aa)
RASL10BRAS like family 10 member B. (203 aa)
TFAP2ETranscription factor AP-2 epsilon. (433 aa)
M3YTP8_MUSPFV-SNARE coiled-coil homology domain-containing protein. (122 aa)
RFX6Regulatory factor X6. (928 aa)
C1QTNF12C1q and TNF related 12. (305 aa)
POMCProopiomelanocortin. (265 aa)
FKBP1BPeptidylprolyl isomerase. (209 aa)
RPH3ALRabphilin 3A like (without C2 domains). (301 aa)
DOC2BDouble C2 domain beta. (376 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (210 aa)
BIRC5Baculoviral IAP repeat containing 5. (142 aa)
LIFLIF interleukin 6 family cytokine. (202 aa)
OSMOncostatin M. (238 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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