STRINGSTRING
M3YA49_MUSPF M3YA49_MUSPF NDEL1 NDEL1 AP3M2 AP3M2 TRIM46 TRIM46 DTNBP1 DTNBP1 AP3D1 AP3D1 SNAPIN SNAPIN BLOC1S3 BLOC1S3 BLOC1S4 BLOC1S4 AP3S2 AP3S2 AP3B2 AP3B2 FYCO1 FYCO1 BICDL2 BICDL2 NDE1 NDE1 KIF5B KIF5B PAFAH1B1 PAFAH1B1 FBXW11 FBXW11 CLN3 CLN3 TRAK1 TRAK1 HTT HTT M3YHI3_MUSPF M3YHI3_MUSPF BLOC1S6 BLOC1S6 RAB1B RAB1B TRAK2 TRAK2 M3XME4_MUSPF M3XME4_MUSPF M3XNC9_MUSPF M3XNC9_MUSPF DYNC1I1 DYNC1I1 DYNC1H1 DYNC1H1 BICDL1 BICDL1 AP3M1 AP3M1 AP3B1 AP3B1 RAB1A RAB1A M3YA60_MUSPF M3YA60_MUSPF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
M3YA49_MUSPFUncharacterized protein. (659 aa)
NDEL1NudE neurodevelopment protein 1 like 1. (359 aa)
AP3M2AP-3 complex subunit mu-2. (418 aa)
TRIM46Tripartite motif containing 46. (700 aa)
DTNBP1Dystrobrevin binding protein 1. (349 aa)
AP3D1AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. (1151 aa)
SNAPINSNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa)
BLOC1S3Biogenesis of lysosome-related organelles complex 1 subunit 3; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). Belongs to the BLOC1S3 family. (199 aa)
BLOC1S4Biogenesis of lysosomal organelles complex 1 subunit 4. (218 aa)
AP3S2Adaptor related protein complex 3 subunit sigma 2. (193 aa)
AP3B2AP-3 complex subunit beta. (1083 aa)
FYCO1FYVE and coiled-coil domain containing 1. (1441 aa)
BICDL2Coiled-coil domain containing 64B. (505 aa)
NDE1NudE neurodevelopment protein 1. (346 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (963 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
FBXW11F-box and WD repeat domain containing 11. (527 aa)
CLN3Battenin. (438 aa)
TRAK1Trafficking kinesin protein 1. (953 aa)
HTTHuntingtin. (3018 aa)
M3YHI3_MUSPFUncharacterized protein. (174 aa)
BLOC1S6Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...] (172 aa)
RAB1BRAB1B, member RAS oncoprotein family. (210 aa)
TRAK2Uncharacterized protein. (698 aa)
M3XME4_MUSPFHAP1 N-terminal domain-containing protein. (150 aa)
M3XNC9_MUSPFBiogenesis of lysosome-related organelles complex 1 subunit 5; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). (185 aa)
DYNC1I1Dynein cytoplasmic 1 intermediate chain 1. (628 aa)
DYNC1H1Dynein cytoplasmic 1 heavy chain 1. (4469 aa)
BICDL1BICD family like cargo adaptor 1. (598 aa)
AP3M1AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family. (446 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1090 aa)
RAB1ARAB1A, member RAS oncogene family. (251 aa)
M3YA60_MUSPFN-terminal Ras-GEF domain-containing protein. (178 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.