Your Input: | |||||
NF1 | Neurofibromin 1. (2815 aa) | ||||
MED31 | Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (131 aa) | ||||
INCA1 | Inhibitor of CDK, cyclin A1 interacting protein 1. (248 aa) | ||||
ESR1 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (597 aa) | ||||
DACH1 | Dachshund family transcription factor 1. (517 aa) | ||||
EMD | Emerin. (260 aa) | ||||
GAS6 | Growth arrest specific 6. (541 aa) | ||||
EREG | Epiregulin. (161 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (375 aa) | ||||
TP53INP1 | Tumor protein p53 inducible nuclear protein 1. (239 aa) | ||||
WAPL | WAPL cohesin release factor. (1196 aa) | ||||
CDK6 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) | ||||
MORC3 | MORC family CW-type zinc finger 3. (765 aa) | ||||
CTC1 | CST telomere replication complex component 1. (1216 aa) | ||||
M3Y9K9_MUSPF | Integrin beta; Belongs to the integrin beta chain family. (645 aa) | ||||
DAB2IP | DAB2 interacting protein. (1112 aa) | ||||
CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa) | ||||
WNT2 | Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa) | ||||
M3Y377_MUSPF | NTR domain-containing protein. (233 aa) | ||||
PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1087 aa) | ||||
AQP1 | Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa) | ||||
M3Y103_MUSPF | Pex2_Pex12 domain-containing protein. (295 aa) | ||||
CDC73 | Cell division cycle 73. (531 aa) | ||||
DDR2 | Discoidin domain receptor tyrosine kinase 2. (924 aa) | ||||
ZMIZ1 | Zinc finger MIZ-type containing 1. (937 aa) | ||||
M3XVN2_MUSPF | Uncharacterized protein. (213 aa) | ||||
PLA2G1B | Phospholipase A(2). (148 aa) | ||||
MED25 | Mediator complex subunit 25. (836 aa) | ||||
MYC | V-myc myelocytomatosis viral oncoprotein-like protein. (453 aa) | ||||
B4GALT7 | Beta-1,4-galactosyltransferase 7. (327 aa) | ||||
FBXO4 | F-box protein 4. (387 aa) | ||||
C1QL4 | Complement C1q like 4. (259 aa) | ||||
WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (340 aa) | ||||
NGFR | Nerve growth factor receptor. (429 aa) | ||||
IFI30 | IFI30 lysosomal thiol reductase. (252 aa) | ||||
LZTS2 | Leucine zipper putative tumor suppressor 2; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta- catenin. (670 aa) | ||||
FNDC3B | Fibronectin type III domain containing 3B. (1206 aa) | ||||
PML | Promyelocytic leukemia. (876 aa) | ||||
PAWR | Pro-apoptotic WT1 regulator. (360 aa) | ||||
TGFB1 | Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa) | ||||
E2F1 | E2F transcription factor 1. (354 aa) | ||||
PDGFA | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa) | ||||
FOSL2 | FOS like 2, AP-1 transcription factor subunit. (287 aa) | ||||
G9KG30_MUSPF | Peroxisomal membrane protein 3, 35kDa. (305 aa) | ||||
LIG4 | DNA ligase. (911 aa) | ||||
TRIM32 | Tripartite motif containing 32. (673 aa) | ||||
JUN | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa) | ||||
DHX9 | DExH-box helicase 9. (1200 aa) | ||||
IGF1 | Insulin like growth factor 1. (153 aa) | ||||
M3YKW3_MUSPF | RING-type domain-containing protein. (326 aa) | ||||
M3YLE1_MUSPF | Uncharacterized protein. (447 aa) | ||||
ABL1 | Tyrosine-protein kinase. (1150 aa) | ||||
LIF | LIF interleukin 6 family cytokine. (202 aa) | ||||
PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (242 aa) | ||||
SPHK1 | Sphingosine kinase 1. (386 aa) | ||||
CD74 | CD74 molecule. (279 aa) | ||||
CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) | ||||
M3YS01_MUSPF | Ig-like domain-containing protein. (306 aa) | ||||
ZMPSTE24 | CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa) | ||||
NDUFS4 | NADH:ubiquinone oxidoreductase subunit S4. (127 aa) | ||||
FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa) |