(42 nodes) Synaptic vesicle endocytosis network (Mustela putorius)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CANX	Calnexin. (484 aa)
	DNAJC6	DnaJ heat shock protein family (Hsp40) member C6. (944 aa)
	NOSTRIN	Nitric oxide synthase trafficking. (496 aa)
	M3XPT3_MUSPF	COesterase domain-containing protein. (816 aa)
	SYNJ1	Synaptojanin 1. (1578 aa)
	ITSN1	Intersectin 1. (955 aa)
	M3XQF6_MUSPF	DH domain-containing protein. (347 aa)
	PACSIN1	Protein kinase C and casein kinase substrate in neurons 1. (444 aa)
	SH3GL2	SH3 domain containing GRB2 like 2, endophilin A1. (325 aa)
	BTBD8	BTB domain containing 8. (1406 aa)
	OPHN1	Oligophrenin 1. (621 aa)
	NLGN3	Neuroligin 3. (879 aa)
	SH3GL1	SH3 domain containing GRB2 like 1, endophilin A2. (368 aa)
	SYNJ2	Synaptojanin 2. (1301 aa)
	SNAP91	Synaptosome associated protein 91. (905 aa)
	M3Y3A6_MUSPF	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (853 aa)
	SYT8	Synaptotagmin 8. (391 aa)
	SYT5	Synaptotagmin 5. (386 aa)
	SCRIB	Scribble planar cell polarity protein. (1523 aa)
	M3Y9V8_MUSPF	V-SNARE coiled-coil homology domain-containing protein. (119 aa)
	STON2	Stonin-2; Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating; Belongs to the Stoned B family. (952 aa)
	LRRC1	Leucine rich repeat containing 1. (524 aa)
	SNCG	Gamma-synuclein; Belongs to the synuclein family. (127 aa)
	NLGN2	Neuroligin 2. (661 aa)
	PICALM	Phosphatidylinositol binding clathrin assembly protein. (660 aa)
	LOC106004699	Uncharacterized protein. (178 aa)
	SYT2	Synaptotagmin 2. (495 aa)
	SNCB	Beta-synuclein; Belongs to the synuclein family. (135 aa)
	DNM1	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (864 aa)
	SYP	Synaptophysin. (314 aa)
	DENND1A	DENN domain containing 1A. (1074 aa)
	FCHO2	FCH domain only 2. (801 aa)
	M3YV50_MUSPF	Uncharacterized protein. (559 aa)
	SH3GL3	SH3 domain containing GRB2 like 3, endophilin A3. (347 aa)
	M3YW12_MUSPF	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (458 aa)
	LOC101671843	ENTH domain-containing protein. (443 aa)
	SYNPR	Synaptoporin. (265 aa)
	M3Z0F8_MUSPF	COesterase domain-containing protein. (269 aa)
	NLGN1	Neuroligin 1. (607 aa)
	SYT1	Synaptotagmin 1. (422 aa)
	AMPH	Amphiphysin. (676 aa)
	M3Z596_MUSPF	Alpha-synuclein; Belongs to the synuclein family. (140 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMPH	DNM1	ENSMPUP00000018017	ENSMPUP00000013126	Amphiphysin.	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.922
AMPH	FCHO2	ENSMPUP00000018017	ENSMPUP00000014270	Amphiphysin.	FCH domain only 2.	0.779
AMPH	ITSN1	ENSMPUP00000018017	ENSMPUP00000001300	Amphiphysin.	Intersectin 1.	0.689
AMPH	LOC106004699	ENSMPUP00000018017	ENSMPUP00000010974	Amphiphysin.	Uncharacterized protein.	0.951
AMPH	M3XQF6_MUSPF	ENSMPUP00000018017	ENSMPUP00000001306	Amphiphysin.	DH domain-containing protein.	0.512
AMPH	M3Y3A6_MUSPF	ENSMPUP00000018017	ENSMPUP00000005807	Amphiphysin.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.951
AMPH	M3YW12_MUSPF	ENSMPUP00000018017	ENSMPUP00000015522	Amphiphysin.	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.535
AMPH	PICALM	ENSMPUP00000018017	ENSMPUP00000009962	Amphiphysin.	Phosphatidylinositol binding clathrin assembly protein.	0.491
AMPH	SH3GL1	ENSMPUP00000018017	ENSMPUP00000004965	Amphiphysin.	SH3 domain containing GRB2 like 1, endophilin A2.	0.549
AMPH	SH3GL2	ENSMPUP00000018017	ENSMPUP00000003960	Amphiphysin.	SH3 domain containing GRB2 like 2, endophilin A1.	0.593
AMPH	SH3GL3	ENSMPUP00000018017	ENSMPUP00000015393	Amphiphysin.	SH3 domain containing GRB2 like 3, endophilin A3.	0.476
AMPH	STON2	ENSMPUP00000018017	ENSMPUP00000008565	Amphiphysin.	Stonin-2; Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating; Belongs to the Stoned B family.	0.461
AMPH	SYNJ1	ENSMPUP00000018017	ENSMPUP00000001142	Amphiphysin.	Synaptojanin 1.	0.772
AMPH	SYNJ2	ENSMPUP00000018017	ENSMPUP00000005285	Amphiphysin.	Synaptojanin 2.	0.759
CANX	SYP	ENSMPUP00000000684	ENSMPUP00000013725	Calnexin.	Synaptophysin.	0.416
DNAJC6	DNM1	ENSMPUP00000000720	ENSMPUP00000013126	DnaJ heat shock protein family (Hsp40) member C6.	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.713
DNAJC6	LOC101671843	ENSMPUP00000000720	ENSMPUP00000016026	DnaJ heat shock protein family (Hsp40) member C6.	ENTH domain-containing protein.	0.572
DNAJC6	LOC106004699	ENSMPUP00000000720	ENSMPUP00000010974	DnaJ heat shock protein family (Hsp40) member C6.	Uncharacterized protein.	0.713
DNAJC6	M3Y3A6_MUSPF	ENSMPUP00000000720	ENSMPUP00000005807	DnaJ heat shock protein family (Hsp40) member C6.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.713
DNAJC6	M3Y9V8_MUSPF	ENSMPUP00000000720	ENSMPUP00000008115	DnaJ heat shock protein family (Hsp40) member C6.	V-SNARE coiled-coil homology domain-containing protein.	0.557