(93 nodes) Camera-type eye morphogenesis network (Mustela putorius)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FOXF2	Forkhead box F2. (415 aa)
	LCTL	Lactase like; Belongs to the glycosyl hydrolase 1 family. (567 aa)
	CNTF	Ciliary neurotrophic factor. (200 aa)
	RPGRIP1	RPGR interacting protein 1. (1258 aa)
	TSKU	Tsukushi, small leucine rich proteoglycan. (388 aa)
	CITED2	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (273 aa)
	GLI3	GLI family zinc finger 3. (1585 aa)
	TBC1D20	TBC1 domain family member 20. (351 aa)
	FRS2	Fibroblast growth factor receptor substrate 2. (517 aa)
	STRA6	Stimulated by retinoic acid 6. (684 aa)
	BBS4	Bardet-Biedl syndrome 4. (507 aa)
	PDE6C	Phosphodiesterase. (846 aa)
	PITX3	Homeobox protein. (314 aa)
	SDK1	Sidekick cell adhesion molecule 1. (1502 aa)
	MFN2	Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
	EPHA2	EPH receptor A2. (975 aa)
	EPHB2	EPH receptor B2. (963 aa)
	SOX8	SRY-box transcription factor 8. (377 aa)
	PHACTR4	Phosphatase and actin regulator. (708 aa)
	TBX2	T-box transcription factor 2. (679 aa)
	LHX1	LIM homeobox 1. (406 aa)
	M3YU18_MUSPF	Uncharacterized protein. (148 aa)
	COL8A2	Collagen type VIII alpha 2 chain. (703 aa)
	AHI1	Abelson helper integration site 1. (1171 aa)
	NF1	Neurofibromin 1. (2815 aa)
	SOX9	SRY-box transcription factor 9. (522 aa)
	MFSD2A	Major facilitator superfamily domain containing 2A. (529 aa)
	SDK2	Sidekick cell adhesion molecule 2. (2172 aa)
	CRB2	Crumbs cell polarity complex component 2. (1195 aa)
	SP3	Sp3 transcription factor. (695 aa)
	ROM1	Retinal outer segment membrane protein 1. (351 aa)
	IGSF22	Immunoglobulin superfamily member 22. (1325 aa)
	PROX1	Prospero homeobox 1. (737 aa)
	M3YPM9_MUSPF	BZIP domain-containing protein. (351 aa)
	USH1C	USH1 protein network component harmonin. (939 aa)
	NF2	Neurofibromin 2. (591 aa)
	ZEB1	Zinc finger E-box binding homeobox 1. (1109 aa)
	MAN2A1	Alpha-mannosidase. (1143 aa)
	THRB	Thyroid hormone receptor beta. (461 aa)
	MYPN	Myopalladin. (1320 aa)
	IMPG2	Interphotoreceptor matrix proteoglycan 2. (1111 aa)
	NOTCH1	Notch receptor 1. (2119 aa)
	COL8A1	Collagen type VIII alpha 1 chain. (744 aa)
	PAX6	Paired box 6. (436 aa)
	CALB1	Calbindin 1. (261 aa)
	ALDH1A3	Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (512 aa)
	VSX1	Visual system homeobox 1. (363 aa)
	M3YGQ6_MUSPF	Uncharacterized protein. (2662 aa)
	FAT3	FAT atypical cadherin 3. (4612 aa)
	STAT3	Signal transducer and activator of transcription. (770 aa)
	RP1	RP1 axonemal microtubule associated. (2148 aa)
	FAT1	FAT atypical cadherin 1. (4588 aa)
	NAGLU	N-acetyl-alpha-glucosaminidase. (749 aa)
	CRB1	Crumbs cell polarity complex component 1. (1411 aa)
	M3YFG7_MUSPF	Uncharacterized protein. (135 aa)
	M3YEN4_MUSPF	BZIP domain-containing protein. (358 aa)
	M3YE80_MUSPF	SHSP domain-containing protein; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (214 aa)
	EPHB1	EPH receptor B1. (984 aa)
	RORB	RAR related orphan receptor B. (459 aa)
	PITX2	Homeobox protein. (317 aa)
	TTC8	Tetratricopeptide repeat domain 8. (590 aa)
	RDH13	Retinol dehydrogenase 13; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (329 aa)
	TSPAN12	Tetraspanin. (305 aa)
	DLL1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (602 aa)
	CDON	Cell adhesion associated, oncogene regulated. (1260 aa)
	JAG1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
	HIF1A	Hypoxia inducible factor 1 subunit alpha. (824 aa)
	TDRD7	Tudor domain containing 7. (1098 aa)
	NRL	Neural retina leucine zipper. (290 aa)
	M3Y2F6_MUSPF	Uncharacterized protein. (181 aa)
	THY1	Thy-1 cell surface antigen. (161 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	HIPK1	Homeodomain interacting protein kinase 1. (1210 aa)
	KDR	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1355 aa)
	AQP1	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
	LRP5	Uncharacterized protein. (1465 aa)
	BCAR3	BCAR3 adaptor protein, NSP family member. (825 aa)
	CABP4	Calcium binding protein 4. (277 aa)
	HIPK2	Homeodomain interacting protein kinase 2. (1165 aa)
	FOXN4	Forkhead box N4. (514 aa)
	GNAT2	G protein subunit alpha transducin 2. (357 aa)
	VAX1	Ventral anterior homeobox 1. (263 aa)
	RPGRIP1L	RPGRIP1 like. (1346 aa)
	RS1	Retinoschisin 1. (224 aa)
	BAK1	BCL2 antagonist/killer 1. (211 aa)
	RING1	Ring finger protein 1. (406 aa)
	NTRK2	Neurotrophic receptor tyrosine kinase 2. (477 aa)
	PROM1	Prominin 1. (772 aa)
	KDM2B	Lysine demethylase 2B. (1310 aa)
	NOTCH2	Notch receptor 2. (2471 aa)
	GDF11	Growth differentiation factor 11. (404 aa)
	TFAP2A	Transcription factor AP-2 alpha. (384 aa)
	MEGF11	Multiple EGF like domains 11. (1140 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHI1	RPGRIP1	ENSMPUP00000014707	ENSMPUP00000000162	Abelson helper integration site 1.	RPGR interacting protein 1.	0.553
AHI1	RPGRIP1L	ENSMPUP00000014707	ENSMPUP00000003306	Abelson helper integration site 1.	RPGRIP1 like.	0.822
ALDH1A3	STRA6	ENSMPUP00000010828	ENSMPUP00000017161	Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family.	Stimulated by retinoic acid 6.	0.468
BBS4	M3YFG7_MUSPF	ENSMPUP00000017060	ENSMPUP00000010074	Bardet-Biedl syndrome 4.	Uncharacterized protein.	0.426
BBS4	RPGRIP1L	ENSMPUP00000017060	ENSMPUP00000003306	Bardet-Biedl syndrome 4.	RPGRIP1 like.	0.511
BBS4	TTC8	ENSMPUP00000017060	ENSMPUP00000008119	Bardet-Biedl syndrome 4.	Tetratricopeptide repeat domain 8.	0.999
BMP4	CNTF	ENSMPUP00000005423	ENSMPUP00000000308	Bone morphogenetic protein 4.	Ciliary neurotrophic factor.	0.412
BMP4	COL8A1	ENSMPUP00000005423	ENSMPUP00000011221	Bone morphogenetic protein 4.	Collagen type VIII alpha 1 chain.	0.492
BMP4	JAG1	ENSMPUP00000005423	ENSMPUP00000006461	Bone morphogenetic protein 4.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.666
BMP4	KDR	ENSMPUP00000005423	ENSMPUP00000005134	Bone morphogenetic protein 4.	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.487
BMP4	PAX6	ENSMPUP00000005423	ENSMPUP00000011203	Bone morphogenetic protein 4.	Paired box 6.	0.526
BMP4	PITX2	ENSMPUP00000005423	ENSMPUP00000008426	Bone morphogenetic protein 4.	Homeobox protein.	0.411
BMP4	SOX9	ENSMPUP00000005423	ENSMPUP00000014195	Bone morphogenetic protein 4.	SRY-box transcription factor 9.	0.589
BMP4	STAT3	ENSMPUP00000005423	ENSMPUP00000010432	Bone morphogenetic protein 4.	Signal transducer and activator of transcription.	0.421
CABP4	RPGRIP1	ENSMPUP00000003888	ENSMPUP00000000162	Calcium binding protein 4.	RPGR interacting protein 1.	0.530
CALB1	PAX6	ENSMPUP00000010941	ENSMPUP00000011203	Calbindin 1.	Paired box 6.	0.801
CALB1	SOX9	ENSMPUP00000010941	ENSMPUP00000014195	Calbindin 1.	SRY-box transcription factor 9.	0.441
CDON	GLI3	ENSMPUP00000006536	ENSMPUP00000018032	Cell adhesion associated, oncogene regulated.	GLI family zinc finger 3.	0.698
CITED2	HIF1A	ENSMPUP00000018764	ENSMPUP00000006460	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2.	Hypoxia inducible factor 1 subunit alpha.	0.497
CITED2	TFAP2A	ENSMPUP00000018764	ENSMPUP00000000595	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2.	Transcription factor AP-2 alpha.	0.528