(18 nodes) Embryonic camera-type eye morphogenesis network (Mustela putorius)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	M3YFG7_MUSPF	Uncharacterized protein. (135 aa)
	CITED2	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (273 aa)
	FRS2	Fibroblast growth factor receptor substrate 2. (517 aa)
	STRA6	Stimulated by retinoic acid 6. (684 aa)
	PHACTR4	Phosphatase and actin regulator. (708 aa)
	TBX2	T-box transcription factor 2. (679 aa)
	SP3	Sp3 transcription factor. (695 aa)
	PROX1	Prospero homeobox 1. (737 aa)
	ZEB1	Zinc finger E-box binding homeobox 1. (1109 aa)
	PAX6	Paired box 6. (436 aa)
	ALDH1A3	Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (512 aa)
	M3YE80_MUSPF	SHSP domain-containing protein; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (214 aa)
	HIPK1	Homeodomain interacting protein kinase 1. (1210 aa)
	HIPK2	Homeodomain interacting protein kinase 2. (1165 aa)
	VAX1	Ventral anterior homeobox 1. (263 aa)
	KDM2B	Lysine demethylase 2B. (1310 aa)
	TFAP2A	Transcription factor AP-2 alpha. (384 aa)
	FOXF2	Forkhead box F2. (415 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALDH1A3	STRA6	ENSMPUP00000010828	ENSMPUP00000017161	Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family.	Stimulated by retinoic acid 6.	0.468
CITED2	TFAP2A	ENSMPUP00000018764	ENSMPUP00000000595	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2.	Transcription factor AP-2 alpha.	0.528
HIPK1	HIPK2	ENSMPUP00000005316	ENSMPUP00000003715	Homeodomain interacting protein kinase 1.	Homeodomain interacting protein kinase 2.	0.808
HIPK2	HIPK1	ENSMPUP00000003715	ENSMPUP00000005316	Homeodomain interacting protein kinase 2.	Homeodomain interacting protein kinase 1.	0.808
PAX6	TFAP2A	ENSMPUP00000011203	ENSMPUP00000000595	Paired box 6.	Transcription factor AP-2 alpha.	0.474
STRA6	ALDH1A3	ENSMPUP00000017161	ENSMPUP00000010828	Stimulated by retinoic acid 6.	Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family.	0.468
TFAP2A	CITED2	ENSMPUP00000000595	ENSMPUP00000018764	Transcription factor AP-2 alpha.	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2.	0.528
TFAP2A	PAX6	ENSMPUP00000000595	ENSMPUP00000011203	Transcription factor AP-2 alpha.	Paired box 6.	0.474