STRINGSTRING
AXIN2 AXIN2 SMAD3 SMAD3 COL2A1 COL2A1 NKX3-2 NKX3-2 BMP6 BMP6 TFAP2A TFAP2A SP5 SP5 DLX2 DLX2 INSIG2 INSIG2 EXT1 EXT1 PAX1 PAX1 OTOR OTOR RFLNA RFLNA DLX5 DLX5 NAB2 NAB2 BMPR1B BMPR1B P2RX7 P2RX7 CSRNP1 CSRNP1 WDR48 WDR48 RAB23 RAB23 TIPARP TIPARP M3XUW2_MUSPF M3XUW2_MUSPF IFT80 IFT80 GSC GSC ACTN3 ACTN3 PRKRA PRKRA IRX5 IRX5 TMEM119 TMEM119 DLG1 DLG1 ALX3 ALX3 TRPV4 TRPV4 M3XY99_MUSPF M3XY99_MUSPF M3XYC1_MUSPF M3XYC1_MUSPF SGPL1 SGPL1 MEF2D MEF2D NODAL NODAL LRP5 LRP5 COL13A1 COL13A1 FGF4 FGF4 MED12 MED12 HOXA2 HOXA2 HOXA3 HOXA3 HOXA5 HOXA5 HOXA7 HOXA7 M3Y0B9_MUSPF M3Y0B9_MUSPF HOXA11 HOXA11 NPPC NPPC MYF5 MYF5 PAPPA2 PAPPA2 BMP4 BMP4 THBS3 THBS3 PDGFRA PDGFRA M3Y377_MUSPF M3Y377_MUSPF HOXC4 HOXC4 HOXC9 HOXC9 HOXC11 HOXC11 WDR19 WDR19 ALX4 ALX4 EXT2 EXT2 RARG RARG SIX1 SIX1 SIX4 SIX4 HHIP HHIP SLC39A3 SLC39A3 TGFBR1 TGFBR1 MMP13 MMP13 MMP14 MMP14 CYP26B1 CYP26B1 ANKRD11 ANKRD11 MEGF8 MEGF8 TRIP11 TRIP11 MSX1 MSX1 MEF2C MEF2C SATB2 SATB2 SLC39A1 SLC39A1 DLG2 DLG2 TMEM107 TMEM107 FOXN3 FOXN3 WNT9B WNT9B IFITM5 IFITM5 ZFAND5 ZFAND5 SERPINH1 SERPINH1 FGF6 FGF6 TULP3 TULP3 RYK RYK INSIG1 INSIG1 M3YE56_MUSPF M3YE56_MUSPF WWOX WWOX WDR60 WDR60 TIFAB TIFAB GLG1 GLG1 RDH10 RDH10 MTHFD1L MTHFD1L IMPAD1 IMPAD1 EYA1 EYA1 SULF1 SULF1 MMP16 MMP16 LTBP3 LTBP3 SIX2 SIX2 M3YKW3_MUSPF M3YKW3_MUSPF CHST11 CHST11 RARB RARB EIF4A3 EIF4A3 COL3A1 COL3A1 M3YM13_MUSPF M3YM13_MUSPF RUNX2 RUNX2 SCUBE2 SCUBE2 CSGALNACT1 CSGALNACT1 FGF18 FGF18 ZEB1 ZEB1 HYAL2 HYAL2 FLVCR1 FLVCR1 MDFI MDFI ANXA6 ANXA6 OSR1 OSR1 RFLNB RFLNB CDX1 CDX1 ATF2 ATF2 HOXD10 HOXD10 HOXD9 HOXD9 HOXD4 HOXD4 HOXD3 HOXD3 PPARGC1B PPARGC1B ZMPSTE24 ZMPSTE24 SOX9 SOX9 CCN2 CCN2 WNT10B WNT10B PEX7 PEX7 NLE1 NLE1 NIPBL NIPBL SETD2 SETD2 LHX1 LHX1 PCGF2 PCGF2 TBX4 TBX4 LTF LTF M3YUX6_MUSPF M3YUX6_MUSPF OSR2 OSR2 HOXB1 HOXB1 HOXB2 HOXB2 HOXB4 HOXB4 HOXB5 HOXB5 HOXB6 HOXB6 HOXB7 HOXB7 HOXB8 HOXB8 HOXB9 HOXB9 PHOSPHO1 PHOSPHO1 PKD1 PKD1 MATN1 MATN1 COMP COMP FGR FGR IFT140 IFT140 ALPL ALPL RAB33B RAB33B DHRS3 DHRS3 M3YYR0_MUSPF M3YYR0_MUSPF TCF15 TCF15 GLI3 GLI3 SFRP4 SFRP4 M3Z4C1_MUSPF M3Z4C1_MUSPF CITED2 CITED2 PHOSPHO2 PHOSPHO2 NEUROG1 NEUROG1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AXIN2Axin 2. (842 aa)
SMAD3Mothers against decapentaplegic homolog. (414 aa)
COL2A1Collagen type II alpha 1 chain. (1486 aa)
NKX3-2NK3 homeobox 2. (331 aa)
BMP6Bone morphogenetic protein 6. (426 aa)
TFAP2ATranscription factor AP-2 alpha. (384 aa)
SP5Sp5 transcription factor. (397 aa)
DLX2Distal-less homeobox 2. (332 aa)
INSIG2Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (225 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
PAX1Paired box 1. (452 aa)
OTOROtoraplin. (129 aa)
RFLNARefilin A. (216 aa)
DLX5Distal-less homeobox 5. (289 aa)
NAB2NGFI-A binding protein 2. (525 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (514 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (594 aa)
CSRNP1Cysteine and serine rich nuclear protein 1. (606 aa)
WDR48WD repeat domain 48. (429 aa)
RAB23RAB23, member RAS oncogene family. (238 aa)
TIPARPTCDD inducible poly(ADP-ribose) polymerase. (657 aa)
M3XUW2_MUSPFSCHIP-1 domain-containing protein. (463 aa)
IFT80Intraflagellar transport 80. (766 aa)
GSCGoosecoid homeobox. (256 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (904 aa)
PRKRAProtein activator of interferon induced protein kinase EIF2AK2. (313 aa)
IRX5Iroquois homeobox 5. (518 aa)
TMEM119Transmembrane protein 119. (254 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (927 aa)
ALX3ALX homeobox 3. (296 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (873 aa)
M3XY99_MUSPFUncharacterized protein. (1418 aa)
M3XYC1_MUSPFUncharacterized protein. (107 aa)
SGPL1Sphingosine-1-phosphate lyase 1. (582 aa)
MEF2DMyocyte enhancer factor 2D. (454 aa)
NODALNodal growth differentiation factor. (348 aa)
LRP5Uncharacterized protein. (1465 aa)
COL13A1Collagen type XIII alpha 1 chain. (765 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
MED12Mediator complex subunit 12. (2168 aa)
HOXA2Homeobox A2. (378 aa)
HOXA3Homeobox A3. (443 aa)
HOXA5Homeobox A5. (270 aa)
HOXA7Homeobox A7. (214 aa)
M3Y0B9_MUSPFHomeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (271 aa)
HOXA11Homeobox A11. (269 aa)
NPPCNatriuretic peptide C. (126 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
PAPPA2Pappalysin 2. (1785 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
THBS3Thrombospondin 3. (956 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1087 aa)
M3Y377_MUSPFNTR domain-containing protein. (233 aa)
HOXC4Homeobox C4. (264 aa)
HOXC9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (260 aa)
HOXC11Homeobox C11. (304 aa)
WDR19WD repeat domain 19. (1342 aa)
ALX4ALX homeobox 4. (409 aa)
EXT2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (760 aa)
RARGRetinoic acid receptor gamma. (458 aa)
SIX1SIX homeobox 1. (284 aa)
SIX4SIX homeobox 4. (455 aa)
HHIPHedgehog interacting protein. (700 aa)
SLC39A3Solute carrier family 39 member 3. (377 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (480 aa)
MMP13Matrix metallopeptidase 13. (511 aa)
MMP14Matrix metallopeptidase 14. (582 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
ANKRD11Ankyrin repeat domain 11. (2631 aa)
MEGF8Multiple EGF like domains 8. (2396 aa)
TRIP11Thyroid hormone receptor interactor 11. (1977 aa)
MSX1Msh homeobox 1. (303 aa)
MEF2CMyocyte enhancer factor 2C. (433 aa)
SATB2DNA-binding protein SATB. (733 aa)
SLC39A1Solute carrier family 39, member 1. (329 aa)
DLG2Uncharacterized protein. (833 aa)
TMEM107Transmembrane protein 107. (131 aa)
FOXN3Forkhead box N3. (515 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
IFITM5Interferon induced transmembrane protein 5. (134 aa)
ZFAND5Zinc finger AN1-type containing 5. (213 aa)
SERPINH1Serpin peptidase inhibitor, clade H, member 1; Belongs to the serpin family. (415 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
TULP3Tubby-like protein; Belongs to the TUB family. (462 aa)
RYKReceptor like tyrosine kinase. (478 aa)
INSIG1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. (113 aa)
M3YE56_MUSPFCystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (576 aa)
WWOXWW domain containing oxidoreductase. (462 aa)
WDR60WD repeat domain 60. (998 aa)
TIFABTIFA inhibitor. (211 aa)
GLG1Golgi glycoprotein 1. (957 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
MTHFD1LMethylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (918 aa)
IMPAD1Inositol monophosphatase domain containing 1. (294 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (621 aa)
SULF1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (867 aa)
MMP16Matrix metallopeptidase 16. (562 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1186 aa)
SIX2SIX homeobox 2. (296 aa)
M3YKW3_MUSPFRING-type domain-containing protein. (326 aa)
CHST11Carbohydrate sulfotransferase. (347 aa)
RARBRetinoic acid receptor beta. (448 aa)
EIF4A3Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. (422 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
M3YM13_MUSPFUncharacterized protein. (437 aa)
RUNX2Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (507 aa)
SCUBE2Signal peptide, CUB domain and EGF like domain containing 2. (992 aa)
CSGALNACT1Hexosyltransferase. (410 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1109 aa)
HYAL2Hyaluronidase. (476 aa)
FLVCR1Feline leukemia virus subgroup C cellular receptor 1. (556 aa)
MDFIMyoD family inhibitor. (246 aa)
ANXA6Annexin. (673 aa)
OSR1Odd-skipped related transcription factor 1. (267 aa)
RFLNBRefilin B. (158 aa)
CDX1Caudal type homeobox 1. (265 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
HOXD10Homeobox D10. (410 aa)
HOXD9Homeobox D9. (350 aa)
HOXD4Homeobox D4. (257 aa)
HOXD3Homeobox D3. (430 aa)
PPARGC1BPPARG coactivator 1 beta. (1027 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
SOX9SRY-box transcription factor 9. (522 aa)
CCN2Cellular communication network factor 2. (349 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
PEX7Peroxisomal biogenesis factor 7. (323 aa)
NLE1Notchless homolog 1. (485 aa)
NIPBLNipped-B protein. (2803 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2564 aa)
LHX1LIM homeobox 1. (406 aa)
PCGF2Polycomb group RING finger protein 2. (344 aa)
TBX4T-box transcription factor 4. (553 aa)
LTFLactotransferrin; Belongs to the transferrin family. (711 aa)
M3YUX6_MUSPFUncharacterized protein. (497 aa)
OSR2Odd-skipped related transciption factor 2. (276 aa)
HOXB1Homeobox B1. (301 aa)
HOXB2Homeobox B2. (345 aa)
HOXB4Homeobox B4. (251 aa)
HOXB5Homeobox B5. (269 aa)
HOXB6Homeobox B6. (224 aa)
HOXB7Homeobox B7. (217 aa)
HOXB8Homeobox B8. (243 aa)
HOXB9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (250 aa)
PHOSPHO1Phosphoethanolamine/phosphocholine phosphatase. (305 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4230 aa)
MATN1Matrilin 1. (497 aa)
COMPCartilage oligomeric matrix protein. (756 aa)
FGRTyrosine-protein kinase. (526 aa)
IFT140Intraflagellar transport 140. (1459 aa)
ALPLAlkaline phosphatase. (524 aa)
RAB33BRAB33B, member RAS oncogene family. (229 aa)
DHRS3Dehydrogenase/reductase member 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa)
M3YYR0_MUSPFAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (839 aa)
TCF15Transcription factor 15. (168 aa)
GLI3GLI family zinc finger 3. (1585 aa)
SFRP4Secreted frizzled related protein 4. (346 aa)
M3Z4C1_MUSPFUncharacterized protein. (550 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (273 aa)
PHOSPHO2Phosphatase, orphan 2. (241 aa)
NEUROG1Neurogenin 1. (247 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
Server load: low (30%) [HD]