(19 nodes) Smooth muscle tissue development network (Mustela putorius)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SRF	Serum response factor. (508 aa)
	COL3A1	Collagen type III alpha 1 chain. (1466 aa)
	M3YE59_MUSPF	HH_signal domain-containing protein. (290 aa)
	ZFAND5	Zinc finger AN1-type containing 5. (213 aa)
	DLG2	Uncharacterized protein. (833 aa)
	PTCH1	Patched 1. (1386 aa)
	SMO	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (790 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	DLG1	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (927 aa)
	M3XUW2_MUSPF	SCHIP-1 domain-containing protein. (463 aa)
	TIPARP	TCDD inducible poly(ADP-ribose) polymerase. (657 aa)
	PKD2	Polycystin 2, transient receptor potential cation channel. (915 aa)
	STRA6	Stimulated by retinoic acid 6. (684 aa)
	IHH	Indian hedgehog signaling molecule. (384 aa)
	NF1	Neurofibromin 1. (2815 aa)
	SOX9	SRY-box transcription factor 9. (522 aa)
	OSR1	Odd-skipped related transcription factor 1. (267 aa)
	ENG	Endoglin. (653 aa)
	PROX1	Prospero homeobox 1. (737 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	IHH	ENSMPUP00000005423	ENSMPUP00000016454	Bone morphogenetic protein 4.	Indian hedgehog signaling molecule.	0.663
BMP4	M3YE59_MUSPF	ENSMPUP00000005423	ENSMPUP00000009616	Bone morphogenetic protein 4.	HH_signal domain-containing protein.	0.663
BMP4	PTCH1	ENSMPUP00000005423	ENSMPUP00000006660	Bone morphogenetic protein 4.	Patched 1.	0.537
BMP4	SOX9	ENSMPUP00000005423	ENSMPUP00000014195	Bone morphogenetic protein 4.	SRY-box transcription factor 9.	0.589
DLG1	DLG2	ENSMPUP00000003739	ENSMPUP00000008068	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.	Uncharacterized protein.	0.816
DLG2	DLG1	ENSMPUP00000008068	ENSMPUP00000003739	Uncharacterized protein.	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.	0.816
IHH	BMP4	ENSMPUP00000016454	ENSMPUP00000005423	Indian hedgehog signaling molecule.	Bone morphogenetic protein 4.	0.663
IHH	PTCH1	ENSMPUP00000016454	ENSMPUP00000006660	Indian hedgehog signaling molecule.	Patched 1.	0.984
IHH	SMO	ENSMPUP00000016454	ENSMPUP00000005835	Indian hedgehog signaling molecule.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.786
IHH	SOX9	ENSMPUP00000016454	ENSMPUP00000014195	Indian hedgehog signaling molecule.	SRY-box transcription factor 9.	0.541
M3XUW2_MUSPF	TIPARP	ENSMPUP00000002862	ENSMPUP00000002782	SCHIP-1 domain-containing protein.	TCDD inducible poly(ADP-ribose) polymerase.	0.569
M3XUW2_MUSPF	ZFAND5	ENSMPUP00000002862	ENSMPUP00000008881	SCHIP-1 domain-containing protein.	Zinc finger AN1-type containing 5.	0.767
M3YE59_MUSPF	BMP4	ENSMPUP00000009616	ENSMPUP00000005423	HH_signal domain-containing protein.	Bone morphogenetic protein 4.	0.663
M3YE59_MUSPF	PTCH1	ENSMPUP00000009616	ENSMPUP00000006660	HH_signal domain-containing protein.	Patched 1.	0.977
M3YE59_MUSPF	SMO	ENSMPUP00000009616	ENSMPUP00000005835	HH_signal domain-containing protein.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.741
M3YE59_MUSPF	SOX9	ENSMPUP00000009616	ENSMPUP00000014195	HH_signal domain-containing protein.	SRY-box transcription factor 9.	0.541
PKD2	SMO	ENSMPUP00000002208	ENSMPUP00000005835	Polycystin 2, transient receptor potential cation channel.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.511
PTCH1	BMP4	ENSMPUP00000006660	ENSMPUP00000005423	Patched 1.	Bone morphogenetic protein 4.	0.537
PTCH1	IHH	ENSMPUP00000006660	ENSMPUP00000016454	Patched 1.	Indian hedgehog signaling molecule.	0.984
PTCH1	M3YE59_MUSPF	ENSMPUP00000006660	ENSMPUP00000009616	Patched 1.	HH_signal domain-containing protein.	0.977