STRINGSTRING
RASSF2 RASSF2 BMPR2 BMPR2 VDR VDR PTK2B PTK2B EXT1 EXT1 IL23A IL23A NOTCH2 NOTCH2 TNFSF11 TNFSF11 SPP2 SPP2 CHD7 CHD7 BAK1 BAK1 HNF1A HNF1A PTN PTN TCIRG1 TCIRG1 LRP5 LRP5 CTSK CTSK PLG PLG GPR55 GPR55 SNX10 SNX10 HOXA3 HOXA3 THBS4 THBS4 ACP5 ACP5 TPP1 TPP1 NOL3 NOL3 F2R F2R RAB3D RAB3D BSX BSX M3Y3R7_MUSPF M3Y3R7_MUSPF LIPA LIPA HIF1A HIF1A JAG1 JAG1 WNT16 WNT16 EDNRA EDNRA CAV1 CAV1 ACVRL1 ACVRL1 MEF2C MEF2C DLL4 DLL4 FLNA FLNA ATG5 ATG5 M3YE56_MUSPF M3YE56_MUSPF IL7 IL7 CRB1 CRB1 NOX4 NOX4 P3H4 P3H4 M3YHM6_MUSPF M3YHM6_MUSPF M3YHN0_MUSPF M3YHN0_MUSPF M3YHN1_MUSPF M3YHN1_MUSPF M3YHN2_MUSPF M3YHN2_MUSPF ELF3 ELF3 LGR4 LGR4 IAPP IAPP TRAF6 TRAF6 LTBP3 LTBP3 EPAS1 EPAS1 LIF LIF TIMP1 TIMP1 TPH1 TPH1 TIE1 TIE1 FGF10 FGF10 RSPO3 RSPO3 NCDN NCDN PTH1R PTH1R CTHRC1 CTHRC1 CCR2 CCR2 CCDC154 CCDC154 EPHA2 EPHA2 MITF MITF MDM2 MDM2 TGFB1 TGFB1 AXL AXL SRC SRC SEMA3C SEMA3C GJA5 GJA5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RASSF2Ras association domain family member 2. (326 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1045 aa)
VDRVitamin D receptor. (427 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
IL23AInterleukin 23 subunit alpha. (195 aa)
NOTCH2Notch receptor 2. (2471 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (321 aa)
SPP2Secreted phosphoprotein 2. (203 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2522 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
HNF1AHNF1 homeobox A. (633 aa)
PTNPleiotrophin. (168 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa)
LRP5Uncharacterized protein. (1465 aa)
CTSKCathepsin K; Belongs to the peptidase C1 family. (339 aa)
PLGPlasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (810 aa)
GPR55G protein-coupled receptor 55; Belongs to the G-protein coupled receptor 1 family. (329 aa)
SNX10Sorting nexin 10. (201 aa)
HOXA3Homeobox A3. (443 aa)
THBS4Thrombospondin 4. (964 aa)
ACP5Acid phosphatase 5, tartrate resistant. (335 aa)
TPP1Tripeptidyl peptidase 1. (572 aa)
NOL3Nucleolar protein 3. (217 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (426 aa)
RAB3DRAB3D, member RAS oncogene family. (219 aa)
BSXBrain specific homeobox. (232 aa)
M3Y3R7_MUSPFUncharacterized protein. (144 aa)
LIPALipase; Belongs to the AB hydrolase superfamily. Lipase family. (396 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (824 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
MEF2CMyocyte enhancer factor 2C. (433 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
FLNAFilamin A. (2647 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
M3YE56_MUSPFCystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (576 aa)
IL7Interleukin 7. (158 aa)
CRB1Crumbs cell polarity complex component 1. (1411 aa)
NOX4NADPH oxidase 4. (578 aa)
P3H4Prolyl 3-hydroxylase family member 4 (non-enzymatic). (443 aa)
M3YHM6_MUSPFANK_REP_REGION domain-containing protein. (264 aa)
M3YHN0_MUSPFUncharacterized protein. (221 aa)
M3YHN1_MUSPFRoc domain-containing protein. (313 aa)
M3YHN2_MUSPFProtein kinase domain-containing protein. (625 aa)
ELF3E74 like ETS transcription factor 3. (369 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (890 aa)
IAPPIslet amyloid polypeptide. (89 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1186 aa)
EPAS1Endothelial PAS domain protein 1. (868 aa)
LIFLIF interleukin 6 family cytokine. (202 aa)
TIMP1TIMP metallopeptidase inhibitor 1. (207 aa)
TPH1Tryptophan hydroxylase 1. (502 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (994 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
RSPO3R-spondin 3. (275 aa)
NCDNNeurochondrin. (729 aa)
PTH1RParathyroid hormone 1 receptor; Belongs to the G-protein coupled receptor 2 family. (596 aa)
CTHRC1Collagen triple helix repeat containing 1. (282 aa)
CCR2C-C motif chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family. (337 aa)
CCDC154Coiled-coil domain containing 154. (669 aa)
EPHA2EPH receptor A2. (975 aa)
MITFMelanocyte inducing transcription factor. (520 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (487 aa)
TGFB1Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa)
AXLAXL receptor tyrosine kinase. (887 aa)
SRCTyrosine-protein kinase. (536 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (750 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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