(48 nodes) Presynaptic active zone network (Mustela putorius)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GPER1	G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (359 aa)
	NTNG1	Netrin G1. (581 aa)
	GAD1	Glutamate decarboxylase 1. (594 aa)
	FZD3	Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
	ADCY8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
	PNISR	PNN interacting serine and arginine rich protein. (814 aa)
	M3XUB3_MUSPF	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (445 aa)
	PPFIA3	PTPRF interacting protein alpha 3. (1231 aa)
	TPRG1	Tumor protein p63 regulated 1. (332 aa)
	ARHGAP44	Rho GTPase activating protein 44. (759 aa)
	STX2	Syntaxin 2; Belongs to the syntaxin family. (259 aa)
	PPFIA1	PTPRF interacting protein alpha 1. (1236 aa)
	UNC13B	Unc-13 homolog B. (1598 aa)
	M3Y0C7_MUSPF	Uncharacterized protein. (653 aa)
	VPS11	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (941 aa)
	M3Y2F6_MUSPF	Uncharacterized protein. (181 aa)
	RIMS1	Regulating synaptic membrane exocytosis 1. (1642 aa)
	M3Y7S4_MUSPF	HSac2 domain-containing protein. (149 aa)
	OTOF	Otoferlin. (2000 aa)
	APBA1	Amyloid beta precursor protein binding family A member 1. (832 aa)
	PPFIBP2	PPFIA binding protein 2. (912 aa)
	CTBP1	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (429 aa)
	PPFIA4	PTPRF interacting protein alpha 4. (1267 aa)
	M3YIY7_MUSPF	Uncharacterized protein. (103 aa)
	M3YIZ2_MUSPF	Uncharacterized protein. (522 aa)
	ZZEF1	Zinc finger ZZ-type and EF-hand domain containing 1. (2829 aa)
	STX4	Syntaxin 4; Belongs to the syntaxin family. (297 aa)
	NTNG2	Netrin G2. (531 aa)
	BSN	Bassoon presynaptic cytomatrix protein. (3838 aa)
	STXBP1	Syntaxin binding protein 1; Belongs to the STXBP/unc-18/SEC1 family. (594 aa)
	SYP	Synaptophysin. (314 aa)
	RIMS3	Regulating synaptic membrane exocytosis 3. (308 aa)
	STX3	Syntaxin 3; Belongs to the syntaxin family. (289 aa)
	EGFLAM	EGF like, fibronectin type III and laminin G domains. (986 aa)
	RIMS2	Regulating synaptic membrane exocytosis 2. (1458 aa)
	RAB3A	RAB3A, member RAS oncogene family. (220 aa)
	UNC13A	Unc-13 homolog A. (1731 aa)
	M3YYI0_MUSPF	Uncharacterized protein. (126 aa)
	M3YYI2_MUSPF	Uncharacterized protein. (111 aa)
	ERC2	ELKS/RAB6-interacting/CAST family member 2. (969 aa)
	M3Z041_MUSPF	Uncharacterized protein. (1205 aa)
	NPTN	Neuroplastin. (398 aa)
	SLC32A1	Solute carrier family 32 member 1. (526 aa)
	ERC1	ELKS/RAB6-interacting/CAST family member 1. (886 aa)
	ENSMPUP00000018030	annotation not available (113 aa)
	PCLO	Piccolo presynaptic cytomatrix protein. (4560 aa)
	STX11	Syntaxin 11; Belongs to the syntaxin family. (287 aa)
	STX19	Syntaxin 19; Belongs to the syntaxin family. (291 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APBA1	PPFIA3	ENSMPUP00000009494	ENSMPUP00000003013	Amyloid beta precursor protein binding family A member 1.	PTPRF interacting protein alpha 3.	0.456
APBA1	RIMS1	ENSMPUP00000009494	ENSMPUP00000006221	Amyloid beta precursor protein binding family A member 1.	Regulating synaptic membrane exocytosis 1.	0.418
APBA1	RIMS2	ENSMPUP00000009494	ENSMPUP00000014984	Amyloid beta precursor protein binding family A member 1.	Regulating synaptic membrane exocytosis 2.	0.720
APBA1	RIMS3	ENSMPUP00000009494	ENSMPUP00000014013	Amyloid beta precursor protein binding family A member 1.	Regulating synaptic membrane exocytosis 3.	0.437
APBA1	STX11	ENSMPUP00000009494	ENSMPUP00000018262	Amyloid beta precursor protein binding family A member 1.	Syntaxin 11; Belongs to the syntaxin family.	0.454
APBA1	STX19	ENSMPUP00000009494	ENSMPUP00000019740	Amyloid beta precursor protein binding family A member 1.	Syntaxin 19; Belongs to the syntaxin family.	0.434
APBA1	STX2	ENSMPUP00000009494	ENSMPUP00000004053	Amyloid beta precursor protein binding family A member 1.	Syntaxin 2; Belongs to the syntaxin family.	0.612
APBA1	STX3	ENSMPUP00000009494	ENSMPUP00000014483	Amyloid beta precursor protein binding family A member 1.	Syntaxin 3; Belongs to the syntaxin family.	0.612
APBA1	STX4	ENSMPUP00000009494	ENSMPUP00000011576	Amyloid beta precursor protein binding family A member 1.	Syntaxin 4; Belongs to the syntaxin family.	0.612
APBA1	STXBP1	ENSMPUP00000009494	ENSMPUP00000013715	Amyloid beta precursor protein binding family A member 1.	Syntaxin binding protein 1; Belongs to the STXBP/unc-18/SEC1 family.	0.997
BSN	CTBP1	ENSMPUP00000013679	ENSMPUP00000011090	Bassoon presynaptic cytomatrix protein.	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.489
BSN	ENSMPUP00000018030	ENSMPUP00000013679	ENSMPUP00000018030	Bassoon presynaptic cytomatrix protein.	annotation not available	0.489
BSN	ERC2	ENSMPUP00000013679	ENSMPUP00000016736	Bassoon presynaptic cytomatrix protein.	ELKS/RAB6-interacting/CAST family member 2.	0.431
BSN	M3XUB3_MUSPF	ENSMPUP00000013679	ENSMPUP00000002663	Bassoon presynaptic cytomatrix protein.	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.489
BSN	OTOF	ENSMPUP00000013679	ENSMPUP00000008171	Bassoon presynaptic cytomatrix protein.	Otoferlin.	0.526
BSN	PCLO	ENSMPUP00000013679	ENSMPUP00000018179	Bassoon presynaptic cytomatrix protein.	Piccolo presynaptic cytomatrix protein.	0.566
BSN	RIMS1	ENSMPUP00000013679	ENSMPUP00000006221	Bassoon presynaptic cytomatrix protein.	Regulating synaptic membrane exocytosis 1.	0.430
CTBP1	BSN	ENSMPUP00000011090	ENSMPUP00000013679	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Bassoon presynaptic cytomatrix protein.	0.489
CTBP1	ENSMPUP00000018030	ENSMPUP00000011090	ENSMPUP00000018030	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	annotation not available	0.868
CTBP1	M3XUB3_MUSPF	ENSMPUP00000011090	ENSMPUP00000002663	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.870