STRINGSTRING
BMP10 BMP10 HDAC4 HDAC4 BMPR2 BMPR2 RBPMS2 RBPMS2 EDN1 EDN1 BHLHA15 BHLHA15 NOG NOG ZBED6 ZBED6 GPER1 GPER1 FZD7 FZD7 TRIM32 TRIM32 NEK5 NEK5 NFATC2 NFATC2 MDM2 MDM2 FRS2 FRS2 FBXO22 FBXO22 CAMK1 CAMK1 CAV3 CAV3 MTOR MTOR OLFM2 OLFM2 SUPT6H SUPT6H M3YRT0_MUSPF M3YRT0_MUSPF CDK9 CDK9 ENG ENG MYOD1 MYOD1 PROX1 PROX1 SOX6 SOX6 ZEB1 ZEB1 PRDM6 PRDM6 NKX2-5 NKX2-5 PLPP7 PLPP7 M3YLR8_MUSPF M3YLR8_MUSPF IGF1 IGF1 SIRT1 SIRT1 SOX5 SOX5 MEGF10 MEGF10 TRIM72 TRIM72 NOTCH1 NOTCH1 ATP11A ATP11A M3YG16_MUSPF M3YG16_MUSPF M3YE86_MUSPF M3YE86_MUSPF PTBP1 PTBP1 HDAC5 HDAC5 AKIRIN2 AKIRIN2 SMYD1 SMYD1 ANKRD17 ANKRD17 EREG EREG MECP2 MECP2 BMPR1A BMPR1A SMAD4 SMAD4 CCDC142 CCDC142 MEF2C MEF2C MSX1 MSX1 M3Y830_MUSPF M3Y830_MUSPF CYP26B1 CYP26B1 EZH2 EZH2 MMP14 MMP14 DLL1 DLL1 NFATC3 NFATC3 SMAD1 SMAD1 DNMT1 DNMT1 RBM38 RBM38 BMP2 BMP2 KIT KIT TARBP2 TARBP2 IGF2 IGF2 DMPK DMPK BMP4 BMP4 MYF6 MYF6 MYF5 MYF5 FOXO4 FOXO4 MAPK14 MAPK14 MAMSTR MAMSTR MYOCD MYOCD RBM4 RBM4 TMEM119 TMEM119 ACTN3 ACTN3 PDCD4 PDCD4 CCN3 CCN3 MAML1 MAML1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BMP10Bone morphogenetic protein 10. (424 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1083 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1045 aa)
RBPMS2RNA binding protein, mRNA processing factor 2. (200 aa)
EDN1Endothelin 1. (202 aa)
BHLHA15Basic helix-loop-helix family member a15. (187 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
ZBED6Zinc finger BED-type containing 6. (980 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (359 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
TRIM32Tripartite motif containing 32. (673 aa)
NEK5NIMA related kinase 5. (787 aa)
NFATC2Nuclear factor of activated T cells 2. (912 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (487 aa)
FRS2Fibroblast growth factor receptor substrate 2. (517 aa)
FBXO22F-box protein 22. (408 aa)
CAMK1Calcium/calmodulin dependent protein kinase I; Belongs to the protein kinase superfamily. (409 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2552 aa)
OLFM2Olfactomedin 2. (386 aa)
SUPT6HTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1726 aa)
M3YRT0_MUSPFSCP domain-containing protein; Belongs to the CRISP family. (201 aa)
CDK9Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa)
ENGEndoglin. (653 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
PROX1Prospero homeobox 1. (737 aa)
SOX6SRY-box transcription factor 6. (814 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1109 aa)
PRDM6PR/SET domain 6. (608 aa)
NKX2-5NK2 homeobox 5. (323 aa)
PLPP7Phospholipid phosphatase 7 (inactive). (271 aa)
M3YLR8_MUSPFRHD domain-containing protein. (249 aa)
IGF1Insulin like growth factor 1. (153 aa)
SIRT1Sirtuin 1. (557 aa)
SOX5SRY-box transcription factor 5. (763 aa)
MEGF10Multiple EGF like domains 10. (1081 aa)
TRIM72Tripartite motif containing 72. (471 aa)
NOTCH1Notch receptor 1. (2119 aa)
ATP11APhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1274 aa)
M3YG16_MUSPFBHLH domain-containing protein. (137 aa)
M3YE86_MUSPFUncharacterized protein. (766 aa)
PTBP1Polypyrimidine tract binding protein 1. (557 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1091 aa)
AKIRIN2Akirin 2. (203 aa)
SMYD1SET and MYND domain containing 1. (581 aa)
ANKRD17Ankyrin repeat domain 17. (2491 aa)
EREGEpiregulin. (161 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (484 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (533 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
CCDC142Coiled-coil domain containing 142. (768 aa)
MEF2CMyocyte enhancer factor 2C. (433 aa)
MSX1Msh homeobox 1. (303 aa)
M3Y830_MUSPFProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (417 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (753 aa)
MMP14Matrix metallopeptidase 14. (582 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (602 aa)
NFATC3Nuclear factor of activated T cells 3. (1037 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
DNMT1DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1674 aa)
RBM38RNA binding motif protein 38. (202 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
KITKIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (948 aa)
TARBP2RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...] (365 aa)
IGF2Insulin like growth factor 2. (192 aa)
DMPKDM1 protein kinase. (631 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
MYF6Myogenic factor 6. (242 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
FOXO4Forkhead box O4. (509 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
MAMSTRMEF2 activating motif and SAP domain containing transcriptional regulator. (436 aa)
MYOCDMyocardin. (980 aa)
RBM4RNA binding motif protein 4. (365 aa)
TMEM119Transmembrane protein 119. (254 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (904 aa)
PDCD4Programmed cell death 4. (469 aa)
CCN3Cellular communication network factor 3. (353 aa)
MAML1Mastermind like transcriptional coactivator 1. (789 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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