(21 nodes) Positive regulation of striated muscle cell differentiation network (Mustela putorius)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EDN1	Endothelin 1. (202 aa)
	MAML1	Mastermind like transcriptional coactivator 1. (789 aa)
	ACTN3	Actinin alpha 3 (gene/pseudogene). (904 aa)
	MYOCD	Myocardin. (980 aa)
	MAMSTR	MEF2 activating motif and SAP domain containing transcriptional regulator. (436 aa)
	MAPK14	Mitogen-activated protein kinase. (360 aa)
	MYF5	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
	MYF6	Myogenic factor 6. (242 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	BMP10	Bone morphogenetic protein 10. (424 aa)
	MMP14	Matrix metallopeptidase 14. (582 aa)
	CYP26B1	Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
	MEF2C	Myocyte enhancer factor 2C. (433 aa)
	SMYD1	SET and MYND domain containing 1. (581 aa)
	ATP11A	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1274 aa)
	IGF1	Insulin like growth factor 1. (153 aa)
	PROX1	Prospero homeobox 1. (737 aa)
	MTOR	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2552 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
	NEK5	NIMA related kinase 5. (787 aa)
	TRIM32	Tripartite motif containing 32. (673 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTN3	MYF6	ENSMPUP00000003128	ENSMPUP00000004906	Actinin alpha 3 (gene/pseudogene).	Myogenic factor 6.	0.539
BMP10	BMP4	ENSMPUP00000006259	ENSMPUP00000005423	Bone morphogenetic protein 10.	Bone morphogenetic protein 4.	0.573
BMP4	BMP10	ENSMPUP00000005423	ENSMPUP00000006259	Bone morphogenetic protein 4.	Bone morphogenetic protein 10.	0.573
MAML1	MEF2C	ENSMPUP00000000682	ENSMPUP00000007906	Mastermind like transcriptional coactivator 1.	Myocyte enhancer factor 2C.	0.525
MAPK14	MEF2C	ENSMPUP00000003896	ENSMPUP00000007906	Mitogen-activated protein kinase.	Myocyte enhancer factor 2C.	0.918
MEF2C	MAML1	ENSMPUP00000007906	ENSMPUP00000000682	Myocyte enhancer factor 2C.	Mastermind like transcriptional coactivator 1.	0.525
MEF2C	MAPK14	ENSMPUP00000007906	ENSMPUP00000003896	Myocyte enhancer factor 2C.	Mitogen-activated protein kinase.	0.918
MEF2C	MYF5	ENSMPUP00000007906	ENSMPUP00000004896	Myocyte enhancer factor 2C.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.758
MEF2C	MYF6	ENSMPUP00000007906	ENSMPUP00000004906	Myocyte enhancer factor 2C.	Myogenic factor 6.	0.653
MEF2C	MYOCD	ENSMPUP00000007906	ENSMPUP00000003627	Myocyte enhancer factor 2C.	Myocardin.	0.636
MYF5	MEF2C	ENSMPUP00000004896	ENSMPUP00000007906	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	Myocyte enhancer factor 2C.	0.758
MYF5	MYF6	ENSMPUP00000004896	ENSMPUP00000004906	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	Myogenic factor 6.	0.692
MYF6	ACTN3	ENSMPUP00000004906	ENSMPUP00000003128	Myogenic factor 6.	Actinin alpha 3 (gene/pseudogene).	0.539
MYF6	MEF2C	ENSMPUP00000004906	ENSMPUP00000007906	Myogenic factor 6.	Myocyte enhancer factor 2C.	0.653
MYF6	MYF5	ENSMPUP00000004906	ENSMPUP00000004896	Myogenic factor 6.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.692
MYOCD	MEF2C	ENSMPUP00000003627	ENSMPUP00000007906	Myocardin.	Myocyte enhancer factor 2C.	0.636