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TRIP11 TRIP11 NOG NOG M3Z4C1_MUSPF M3Z4C1_MUSPF GLI3 GLI3 GDF5 GDF5 TGFB1 TGFB1 SULF2 SULF2 SNAI1 SNAI1 M3Z1E7_MUSPF M3Z1E7_MUSPF FGF2 FGF2 M3YZE5_MUSPF M3YZE5_MUSPF BGN BGN RUNX3 RUNX3 COMP COMP MATN1 MATN1 PKD1 PKD1 OSR2 OSR2 PTH1R PTH1R BMP3 BMP3 WNT10B WNT10B CCN2 CCN2 AXIN2 AXIN2 SOX9 SOX9 ZMPSTE24 ZMPSTE24 HOXD3 HOXD3 ATF2 ATF2 ITGB8 ITGB8 MATN3 MATN3 OSR1 OSR1 ANXA6 ANXA6 HAND1 HAND1 SRF SRF HYAL3 HYAL3 HYAL2 HYAL2 ZEB1 ZEB1 FGF18 FGF18 CSGALNACT1 CSGALNACT1 SCUBE2 SCUBE2 MAPK3 MAPK3 RUNX2 RUNX2 M3YM13_MUSPF M3YM13_MUSPF COL3A1 COL3A1 RARB RARB CHST11 CHST11 LTBP3 LTBP3 CD44 CD44 MGP MGP SULF1 SULF1 IMPAD1 IMPAD1 PITX1 PITX1 SMAD5 SMAD5 M3YE56_MUSPF M3YE56_MUSPF FGF6 FGF6 CHRDL2 CHRDL2 SERPINH1 SERPINH1 SNX19 SNX19 IL17F IL17F ARID5A ARID5A DDRGK1 DDRGK1 BMPR1A BMPR1A MEX3C MEX3C SATB2 SATB2 MEF2C MEF2C MSX1 MSX1 CYTL1 CYTL1 EPYC EPYC SMAD1 SMAD1 MMP13 MMP13 HIF1A HIF1A MKKS MKKS BMP7 BMP7 BMP2 BMP2 PBXIP1 PBXIP1 RARG RARG EXT2 EXT2 HOXC4 HOXC4 THBS3 THBS3 SFRP2 SFRP2 BMP4 BMP4 CCN1 CCN1 WNT2B WNT2B MYF5 MYF5 NPPC NPPC HOXA11 HOXA11 GPLD1 GPLD1 HOXA5 HOXA5 OGN OGN HOXA3 HOXA3 ECM1 ECM1 TWSG1 TWSG1 FGF4 FGF4 MEF2D MEF2D NFIB NFIB CREB3L2 CREB3L2 ZBTB16 ZBTB16 TRPV4 TRPV4 SLC39A14 SLC39A14 BBS2 BBS2 BBS1 BBS1 IFT80 IFT80 TAPT1 TAPT1 BMPR1B BMPR1B HAND2 HAND2 CNMD CNMD RB1 RB1 OTOR OTOR RUNX1 RUNX1 CCN3 CCN3 EXT1 EXT1 DLX2 DLX2 EDN1 EDN1 FGF9 FGF9 COL2A1 COL2A1 BMPR2 BMPR2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TRIP11Thyroid hormone receptor interactor 11. (1977 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
M3Z4C1_MUSPFUncharacterized protein. (550 aa)
GLI3GLI family zinc finger 3. (1585 aa)
GDF5Growth differentiation factor 5. (500 aa)
TGFB1Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa)
SULF2Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (954 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
M3Z1E7_MUSPFUncharacterized protein. (109 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
M3YZE5_MUSPFUncharacterized protein. (85 aa)
BGNBiglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (372 aa)
RUNX3Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (412 aa)
COMPCartilage oligomeric matrix protein. (756 aa)
MATN1Matrilin 1. (497 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4230 aa)
OSR2Odd-skipped related transciption factor 2. (276 aa)
PTH1RParathyroid hormone 1 receptor; Belongs to the G-protein coupled receptor 2 family. (596 aa)
BMP3Bone morphogenetic protein 3; Belongs to the TGF-beta family. (367 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
CCN2Cellular communication network factor 2. (349 aa)
AXIN2Axin 2. (842 aa)
SOX9SRY-box transcription factor 9. (522 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
HOXD3Homeobox D3. (430 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (767 aa)
MATN3Matrilin 3. (469 aa)
OSR1Odd-skipped related transcription factor 1. (267 aa)
ANXA6Annexin. (673 aa)
HAND1Heart and neural crest derivatives expressed 1. (215 aa)
SRFSerum response factor. (508 aa)
HYAL3Hyaluronidase. (415 aa)
HYAL2Hyaluronidase. (476 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1109 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
CSGALNACT1Hexosyltransferase. (410 aa)
SCUBE2Signal peptide, CUB domain and EGF like domain containing 2. (992 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (399 aa)
RUNX2Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (507 aa)
M3YM13_MUSPFUncharacterized protein. (437 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
RARBRetinoic acid receptor beta. (448 aa)
CHST11Carbohydrate sulfotransferase. (347 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1186 aa)
CD44CD44 molecule (Indian blood group). (704 aa)
MGPMatrix Gla protein. (103 aa)
SULF1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (867 aa)
IMPAD1Inositol monophosphatase domain containing 1. (294 aa)
PITX1Homeobox protein. (290 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
M3YE56_MUSPFCystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (576 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
CHRDL2Chordin like 2. (430 aa)
SERPINH1Serpin peptidase inhibitor, clade H, member 1; Belongs to the serpin family. (415 aa)
SNX19Sorting nexin 19. (1002 aa)
IL17FUncharacterized protein. (140 aa)
ARID5AAT-rich interaction domain 5A. (646 aa)
DDRGK1DDRGK domain containing 1. (315 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (533 aa)
MEX3CMex-3 RNA binding family member C. (465 aa)
SATB2DNA-binding protein SATB. (733 aa)
MEF2CMyocyte enhancer factor 2C. (433 aa)
MSX1Msh homeobox 1. (303 aa)
CYTL1Cytokine like 1. (135 aa)
EPYCEpiphycan. (321 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
MMP13Matrix metallopeptidase 13. (511 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (824 aa)
MKKSMcKusick-Kaufman syndrome. (467 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
PBXIP1PBX homeobox interacting protein 1. (713 aa)
RARGRetinoic acid receptor gamma. (458 aa)
EXT2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (760 aa)
HOXC4Homeobox C4. (264 aa)
THBS3Thrombospondin 3. (956 aa)
SFRP2Secreted frizzled related protein 2. (294 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
CCN1Cellular communication network factor 1. (382 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
NPPCNatriuretic peptide C. (126 aa)
HOXA11Homeobox A11. (269 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (875 aa)
HOXA5Homeobox A5. (270 aa)
OGNOsteoglycin. (298 aa)
HOXA3Homeobox A3. (443 aa)
ECM1Extracellular matrix protein 1. (564 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (184 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
MEF2DMyocyte enhancer factor 2D. (454 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (570 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
ZBTB16Zinc finger and BTB domain containing 16. (673 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (873 aa)
SLC39A14Solute carrier family 39 member 14. (490 aa)
BBS2Bardet-Biedl syndrome 2 protein homolog. (721 aa)
BBS1BBS1 domain-containing protein. (593 aa)
IFT80Intraflagellar transport 80. (766 aa)
TAPT1Transmembrane anterior posterior transformation 1. (462 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (514 aa)
HAND2Heart and neural crest derivatives expressed 2. (208 aa)
CNMDChondromodulin. (360 aa)
RB1RB transcriptional corepressor 1. (948 aa)
OTOROtoraplin. (129 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa)
CCN3Cellular communication network factor 3. (353 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
DLX2Distal-less homeobox 2. (332 aa)
EDN1Endothelin 1. (202 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
COL2A1Collagen type II alpha 1 chain. (1486 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1045 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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