STRINGSTRING
OS9 OS9 TNF TNF DERL2 DERL2 JUP JUP GCC2 GCC2 ERLEC1 ERLEC1 CTDSPL2 CTDSPL2 EFNA5 EFNA5 SH3TC1 SH3TC1 TM7SF3 TM7SF3 SEPTIN8 SEPTIN8 NKX6-1 NKX6-1 SYT9 SYT9 LLGL1 LLGL1 MIEF2 MIEF2 CAPN10 CAPN10 DNM1L DNM1L LRRK2 LRRK2 DRD3 DRD3 M3XMV4_MUSPF M3XMV4_MUSPF ACVR1C ACVR1C KLF7 KLF7 UBAC2 UBAC2 M3YJA7_MUSPF M3YJA7_MUSPF NR1H4 NR1H4 IPO5 IPO5 C2CD5 C2CD5 M3YK20_MUSPF M3YK20_MUSPF CEP131 CEP131 PRR5L PRR5L RAB29 RAB29 IGF1 IGF1 PRKCE PRKCE DNAJC1 DNAJC1 TPR TPR M3YL30_MUSPF M3YL30_MUSPF M3YLM3_MUSPF M3YLM3_MUSPF CD2AP CD2AP CLN3 CLN3 BAD BAD LRRC8A LRRC8A PICK1 PICK1 PLA2G6 PLA2G6 GCG GCG OAZ2 OAZ2 XPO4 XPO4 PDZK1 PDZK1 ADTRP ADTRP WLS WLS FRMD4A FRMD4A RACK1 RACK1 ANXA13 ANXA13 MFF MFF AACS AACS ADCY8 ADCY8 ICA1 ICA1 M3XQT7_MUSPF M3XQT7_MUSPF LCP1 LCP1 SIAH3 SIAH3 TLR4 TLR4 ZFAND1 ZFAND1 BLK BLK NR1H2 NR1H2 OPRM1 OPRM1 TCF7L2 TCF7L2 M3XSG3_MUSPF M3XSG3_MUSPF ADRA2A ADRA2A P2RX7 P2RX7 SYTL4 SYTL4 M3XTH1_MUSPF M3XTH1_MUSPF M3XTK1_MUSPF M3XTK1_MUSPF PTPN11 PTPN11 SLC8B1 SLC8B1 RAB23 RAB23 DERL3 DERL3 UQCC2 UQCC2 BAG3 BAG3 PPM1F PPM1F SIRT4 SIRT4 M3XVU1_MUSPF M3XVU1_MUSPF ADIPOQ ADIPOQ NDFIP2 NDFIP2 PPP3CB PPP3CB OAZ3 OAZ3 CHGA CHGA UHMK1 UHMK1 ARHGAP44 ARHGAP44 APOD APOD DRD2 DRD2 MCU MCU DMTN DMTN RAN RAN ZPR1 ZPR1 TCIRG1 TCIRG1 TGFB2 TGFB2 SIDT2 SIDT2 SAR1A SAR1A LRP5 LRP5 ADCY5 ADCY5 M3XZQ7_MUSPF M3XZQ7_MUSPF SNX12 SNX12 M3XZR5_MUSPF M3XZR5_MUSPF GOLPH3L GOLPH3L ANO1 ANO1 FBXW9 FBXW9 REST REST SIRT6 SIRT6 NR1H3 NR1H3 GPLD1 GPLD1 HCLS1 HCLS1 SOX4 SOX4 M3Y0R3_MUSPF M3Y0R3_MUSPF EXOC1 EXOC1 MYOM1 MYOM1 FNDC1 FNDC1 PDX1 PDX1 EZR EZR C2CD2L C2CD2L PTPN22 PTPN22 CD81 CD81 SCFD1 SCFD1 PRKD1 PRKD1 BMP4 BMP4 F2RL1 F2RL1 F2R F2R XPO1 XPO1 INS INS HMGCR HMGCR SORL1 SORL1 M3Y377_MUSPF M3Y377_MUSPF SMO SMO EXPH5 EXPH5 M3Y3J9_MUSPF M3Y3J9_MUSPF M3Y3R5_MUSPF M3Y3R5_MUSPF VPS28 VPS28 PPM1A PPM1A FERMT1 FERMT1 RIPOR1 RIPOR1 ANP32B ANP32B PARD6A PARD6A HIF1A HIF1A PARK7 PARK7 M3Y6M0_MUSPF M3Y6M0_MUSPF TCAF1 TCAF1 ARHGEF5 ARHGEF5 CFTR CFTR FBXW7 FBXW7 TXN TXN ARFIP1 ARFIP1 WWP2 WWP2 M3Y830_MUSPF M3Y830_MUSPF ICE1 ICE1 GRASP GRASP ABCA12 ABCA12 MYH10 MYH10 PDCD5 PDCD5 NDEL1 NDEL1 NDFIP1 NDFIP1 EFCAB7 EFCAB7 HDAC3 HDAC3 M3YA21_MUSPF M3YA21_MUSPF TRIM28 TRIM28 CDK5 CDK5 GSK3B GSK3B BCAP31 BCAP31 APBB3 APBB3 MIDN MIDN MAVS MAVS PKDCC PKDCC SLC25A22 SLC25A22 TGFB3 TGFB3 TFAP2B TFAP2B ABCG1 ABCG1 TMED10 TMED10 GAS6 GAS6 EMD EMD UBE2J1 UBE2J1 SLC9B2 SLC9B2 FLNA FLNA GDI1 GDI1 ADAM9 ADAM9 ALOX5 ALOX5 M3YED7_MUSPF M3YED7_MUSPF M3YEF8_MUSPF M3YEF8_MUSPF NLGN2 NLGN2 SNX3 SNX3 BAG4 BAG4 YOD1 YOD1 RAB11FIP1 RAB11FIP1 ATP2C1 ATP2C1 SAR1B SAR1B PFKL PFKL GPR68 GPR68 AKAP5 AKAP5 TMEM30B TMEM30B ARF6 ARF6 PRNP PRNP GPER1 GPER1 KCNJ11 KCNJ11 SFN SFN INHBB INHBB GJA5 GJA5 SRI SRI GCK GCK GLI3 GLI3 PPID PPID SLC25A18 SLC25A18 HMGN3 HMGN3 STXBP5 STXBP5 PCM1 PCM1 TM9SF4 TM9SF4 EDEM2 EDEM2 ERGIC3 ERGIC3 HNF4A HNF4A PKIG PKIG TGFB1 TGFB1 KCNB1 KCNB1 PTPN1 PTPN1 IFNG IFNG M3Z176_MUSPF M3Z176_MUSPF CSK CSK TRH TRH ANKRD1 ANKRD1 ECT2 ECT2 CAMK1 CAMK1 PDCD10 PDCD10 EDEM1 EDEM1 FAM3D FAM3D ACSL3 ACSL3 TARDBP TARDBP RANGAP1 RANGAP1 ATP13A2 ATP13A2 SLC7A11 SLC7A11 PINK1 PINK1 RHBDF1 RHBDF1 RAB11FIP3 RAB11FIP3 FIS1 FIS1 CNST CNST CIB1 CIB1 M3YWA8_MUSPF M3YWA8_MUSPF BAIAP3 BAIAP3 CEMIP CEMIP STXBP4 STXBP4 GIP GIP GOLPH3 GOLPH3 M3YUN0_MUSPF M3YUN0_MUSPF UBR5 UBR5 M3YUA0_MUSPF M3YUA0_MUSPF ERBB2 ERBB2 CCL5 CCL5 NR1D1 NR1D1 TFAP2E TFAP2E SLC35D3 SLC35D3 ZC3H12A ZC3H12A PRKAA1 PRKAA1 PIK3R1 PIK3R1 KRT20 KRT20 NF1 NF1 M3YSH5_MUSPF M3YSH5_MUSPF GOPC GOPC SH3TC2 SH3TC2 RFX6 RFX6 C1QTNF12 C1QTNF12 SVIP SVIP DNAJC27 DNAJC27 FKBP1B FKBP1B GAPVD1 GAPVD1 LLGL2 LLGL2 B3GAT3 B3GAT3 P3H1 P3H1 GRIPAP1 GRIPAP1 TSG101 TSG101 RBM22 RBM22 RPH3AL RPH3AL DOC2B DOC2B YWHAE YWHAE TREML1 TREML1 TREM2 TREM2 IL6 IL6 TOMM7 TOMM7 SERGEF SERGEF DMAP1 DMAP1 PTPN14 PTPN14 MYO1C MYO1C RHBDF2 RHBDF2 M3YPT2_MUSPF M3YPT2_MUSPF INPP5K INPP5K MIEF1 MIEF1 BIRC5 BIRC5 ITGB1BP1 ITGB1BP1 HMMR HMMR CDK16 CDK16 RSAD2 RSAD2 UBE2G2 UBE2G2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
OS9OS9 endoplasmic reticulum lectin. (672 aa)
TNFTumor necrosis factor alpha; Belongs to the tumor necrosis factor family. (233 aa)
DERL2Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (230 aa)
JUPJunction plakoglobin. (744 aa)
GCC2GRIP and coiled-coil domain containing 2. (1646 aa)
ERLEC1Endoplasmic reticulum lectin 1. (499 aa)
CTDSPL2CTD small phosphatase like 2. (466 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (260 aa)
SH3TC1SH3 domain and tetratricopeptide repeats 1. (1335 aa)
TM7SF3Transmembrane 7 superfamily member 3. (542 aa)
SEPTIN8Septin 8; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (430 aa)
NKX6-1NK6 homeobox 1. (355 aa)
SYT9Synaptotagmin 9. (491 aa)
LLGL1LLGL scribble cell polarity complex component 1. (1074 aa)
MIEF2Mitochondrial elongation factor 2. (459 aa)
CAPN10Calpain 10; Belongs to the peptidase C2 family. (665 aa)
DNM1LDynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (749 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
DRD3Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (447 aa)
M3XMV4_MUSPFUncharacterized protein. (466 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
KLF7Kruppel like factor 7. (302 aa)
UBAC2UBA domain containing 2. (344 aa)
M3YJA7_MUSPF14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (228 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (472 aa)
IPO5Importin 5. (1082 aa)
C2CD5C2 calcium dependent domain containing 5. (1054 aa)
M3YK20_MUSPFWD_REPEATS_REGION domain-containing protein. (237 aa)
CEP131Centrosomal protein 131. (1079 aa)
PRR5LProline rich 5 like. (368 aa)
RAB29RAB29, member RAS oncogene family. (204 aa)
IGF1Insulin like growth factor 1. (153 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa)
DNAJC1DnaJ heat shock protein family (Hsp40) member C1. (555 aa)
TPRTranslocated promoter region, nuclear basket protein. (2439 aa)
M3YL30_MUSPFUncharacterized protein. (1274 aa)
M3YLM3_MUSPFV-SNARE coiled-coil homology domain-containing protein. (496 aa)
CD2APCD2 associated protein. (591 aa)
CLN3Battenin. (438 aa)
BADBCL2 associated agonist of cell death. (168 aa)
LRRC8ALeucine rich repeat containing 8 VRAC subunit A. (810 aa)
PICK1Protein interacting with PRKCA 1. (417 aa)
PLA2G6Phospholipase A2 group VI. (806 aa)
GCGGlucagon. (180 aa)
OAZ2Ornithine decarboxylase antizyme 2. (188 aa)
XPO4Exportin 4. (1043 aa)
PDZK1PDZ domain containing 1. (521 aa)
ADTRPAndrogen dependent TFPI regulating protein. (230 aa)
WLSWnt ligand secretion mediator. (541 aa)
FRMD4AFERM domain containing 4A. (1058 aa)
RACK1WD_REPEATS_REGION domain-containing protein. (317 aa)
ANXA13Annexin. (287 aa)
MFFMitochondrial fission factor. (353 aa)
AACSAcetoacetyl-CoA synthetase. (729 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
ICA1Islet cell autoantigen 1. (510 aa)
M3XQT7_MUSPFUncharacterized protein. (214 aa)
LCP1Lymphocyte cytosolic protein 1. (683 aa)
SIAH3E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (267 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (833 aa)
ZFAND1Zinc finger AN1-type containing 1. (268 aa)
BLKTyrosine-protein kinase. (500 aa)
NR1H2Nuclear receptor subfamily 1 group H member 2. (460 aa)
OPRM1Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (401 aa)
TCF7L2Transcription factor 7 like 2. (514 aa)
M3XSG3_MUSPFCTNNB1_binding domain-containing protein. (169 aa)
ADRA2AAdrenoceptor alpha 2A; Belongs to the G-protein coupled receptor 1 family. (323 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (594 aa)
SYTL4Synaptotagmin like 4. (671 aa)
M3XTH1_MUSPFRhomboid domain-containing protein. (378 aa)
M3XTK1_MUSPFUncharacterized protein. (44 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
SLC8B1Solute carrier family 8 member B1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (588 aa)
RAB23RAB23, member RAS oncogene family. (238 aa)
DERL3Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (231 aa)
UQCC2Ubiquinol-cytochrome c reductase complex assembly factor 2. (136 aa)
BAG3BCL2 associated athanogene 3. (597 aa)
PPM1FProtein phosphatase, Mg2+/Mn2+ dependent 1F. (440 aa)
SIRT4NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (314 aa)
M3XVU1_MUSPFUncharacterized protein. (227 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (244 aa)
NDFIP2Nedd4 family interacting protein 2. (296 aa)
PPP3CBSerine/threonine-protein phosphatase. (479 aa)
OAZ3Ornithine decarboxylase antizyme 3. (232 aa)
CHGAChromogranin A. (448 aa)
UHMK1U2AF homology motif kinase 1. (419 aa)
ARHGAP44Rho GTPase activating protein 44. (759 aa)
APODApolipoprotein D. (189 aa)
DRD2D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. (443 aa)
MCUMitochondrial calcium uniporter. (350 aa)
DMTNDematin actin binding protein. (350 aa)
RANGTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (214 aa)
ZPR1ZPR1 zinc finger. (460 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa)
TGFB2Transforming growth factor beta-2 proprotein; Transforming growth factor beta-2 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively. Transforming growth factor beta-2: Multifunctional protein that regulates various processes such as angiogenesis and heart development (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transfor [...] (414 aa)
SIDT2SID1 transmembrane family member 2. (832 aa)
SAR1ASecretion associated Ras related GTPase 1A; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
LRP5Uncharacterized protein. (1465 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1018 aa)
M3XZQ7_MUSPFUbiquitin-like domain-containing protein. (311 aa)
SNX12Sorting nexin 12. (172 aa)
M3XZR5_MUSPFRBR-type E3 ubiquitin transferase. (115 aa)
GOLPH3LGolgi phosphoprotein 3 like. (287 aa)
ANO1Anoctamin. (888 aa)
FBXW9F-box and WD repeat domain containing 9. (459 aa)
RESTRE1 silencing transcription factor. (1098 aa)
SIRT6Sirtuin 6. (359 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (447 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (875 aa)
HCLS1Hematopoietic cell-specific Lyn substrate 1. (474 aa)
SOX4SRY-box transcription factor 4. (269 aa)
M3Y0R3_MUSPFUncharacterized protein. (201 aa)
EXOC1Exocyst complex component 1. (894 aa)
MYOM1Myomesin 1. (1682 aa)
FNDC1Fibronectin type III domain containing 1. (1906 aa)
PDX1Pancreatic and duodenal homeobox 1. (283 aa)
EZREzrin. (586 aa)
C2CD2LC2CD2 like. (660 aa)
PTPN22Protein tyrosine phosphatase non-receptor type 22. (679 aa)
CD81Tetraspanin. (287 aa)
SCFD1Sec1 family domain containing 1; Belongs to the STXBP/unc-18/SEC1 family. (642 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (824 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
F2RL1F2R like trypsin receptor 1. (397 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (426 aa)
XPO1Exportin 1. (1071 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (109 aa)
HMGCR3-hydroxy-3-methylglutaryl coenzyme A reductase. (914 aa)
SORL1Sortilin related receptor 1. (2211 aa)
M3Y377_MUSPFNTR domain-containing protein. (233 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (790 aa)
EXPH5Exophilin 5. (1998 aa)
M3Y3J9_MUSPFUncharacterized protein. (106 aa)
M3Y3R5_MUSPFUncharacterized protein. (137 aa)
VPS28Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (221 aa)
PPM1AProtein phosphatase, Mg2+/Mn2+ dependent 1A. (455 aa)
FERMT1Fermitin family member 1. (678 aa)
RIPOR1RHO family interacting cell polarization regulator 1. (1319 aa)
ANP32BAcidic nuclear phosphoprotein 32 family member B. (220 aa)
PARD6APar-6 family cell polarity regulator alpha. (346 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (824 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
M3Y6M0_MUSPFPeptidase M60 domain-containing protein. (912 aa)
TCAF1TRPM8 channel associated factor 1. (921 aa)
ARHGEF5Rho guanine nucleotide exchange factor 5. (1595 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1484 aa)
FBXW7F-box and WD repeat domain containing 7. (708 aa)
TXNThioredoxin; Belongs to the thioredoxin family. (105 aa)
ARFIP1ADP ribosylation factor interacting protein 1. (373 aa)
WWP2E3 ubiquitin-protein ligase. (872 aa)
M3Y830_MUSPFProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (417 aa)
ICE1Interactor of little elongation complex ELL subunit 1. (2186 aa)
GRASPGeneral receptor for phosphoinositides 1 associated scaffold protein. (314 aa)
ABCA12ATP binding cassette subfamily A member 12. (2598 aa)
MYH10Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1997 aa)
PDCD5Programmed cell death 5. (125 aa)
NDEL1NudE neurodevelopment protein 1 like 1. (359 aa)
NDFIP1Nedd4 family interacting protein 1. (211 aa)
EFCAB7EF-hand calcium binding domain 7. (663 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (430 aa)
M3YA21_MUSPFWD_REPEATS_REGION domain-containing protein. (467 aa)
TRIM28Tripartite motif containing 28. (700 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (420 aa)
BCAP31B cell receptor associated protein 31. (246 aa)
APBB3Amyloid beta precursor protein binding family B member 3. (486 aa)
MIDNMidnolin. (460 aa)
MAVSMitochondrial antiviral signaling protein. (524 aa)
PKDCCProtein kinase domain containing, cytoplasmic. (294 aa)
SLC25A22Solute carrier family 25 member 22; Belongs to the mitochondrial carrier (TC 2.A.29) family. (323 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa)
TFAP2BTranscription factor AP-2 beta. (476 aa)
ABCG1ATP binding cassette subfamily G member 1. (653 aa)
TMED10Transmembrane p24 trafficking protein 10. (224 aa)
GAS6Growth arrest specific 6. (541 aa)
EMDEmerin. (260 aa)
UBE2J1Ubiquitin conjugating enzyme E2 J1. (303 aa)
SLC9B2Solute carrier family 9 member B2. (538 aa)
FLNAFilamin A. (2647 aa)
GDI1Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. (447 aa)
ADAM9ADAM metallopeptidase domain 9. (785 aa)
ALOX5Arachidonate 5-lipoxygenase. (674 aa)
M3YED7_MUSPFUncharacterized protein. (135 aa)
M3YEF8_MUSPFFOXO-TAD domain-containing protein. (399 aa)
NLGN2Neuroligin 2. (661 aa)
SNX3Sorting nexin 3. (162 aa)
BAG4BCL2 associated athanogene 4. (457 aa)
YOD1YOD1 deubiquitinase. (348 aa)
RAB11FIP1RAB11 family interacting protein 1. (1268 aa)
ATP2C1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (950 aa)
SAR1BSecretion associated Ras related GTPase 1B; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
PFKLATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (751 aa)
GPR68G protein-coupled receptor 68; Belongs to the G-protein coupled receptor 1 family. (360 aa)
AKAP5A-kinase anchoring protein 5. (429 aa)
TMEM30BCell cycle control protein; Belongs to the CDC50/LEM3 family. (342 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
PRNPMajor prion protein; Its primary physiological function is unclear. Has cytoprotective activity against internal or environmental stresses. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan s [...] (257 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (359 aa)
KCNJ11Potassium voltage-gated channel subfamily J member 11. (390 aa)
SFN14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (255 aa)
INHBBInhibin subunit beta B. (238 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
SRISorcin. (198 aa)
GCKPhosphotransferase. (473 aa)
GLI3GLI family zinc finger 3. (1585 aa)
PPIDPeptidylprolyl isomerase D. (370 aa)
SLC25A18Solute carrier family 25 member 18; Belongs to the mitochondrial carrier (TC 2.A.29) family. (322 aa)
HMGN3High mobility group nucleosomal binding domain 3. (180 aa)
STXBP5Syntaxin binding protein 5. (997 aa)
PCM1Pericentriolar material 1. (2134 aa)
TM9SF4Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (638 aa)
EDEM2alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (578 aa)
ERGIC3ERGIC and golgi 3. (383 aa)
HNF4AHepatocyte nuclear factor 4 alpha. (443 aa)
PKIGcAMP-dependent protein kinase inhibitor gamma. (84 aa)
TGFB1Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (858 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (424 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity). (166 aa)
M3Z176_MUSPF14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (221 aa)
CSKTyrosine-protein kinase. (450 aa)
TRHPro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (246 aa)
ANKRD1Ankyrin repeat domain 1. (319 aa)
ECT2Epithelial cell transforming 2. (914 aa)
CAMK1Calcium/calmodulin dependent protein kinase I; Belongs to the protein kinase superfamily. (409 aa)
PDCD10Programmed cell death 10. (212 aa)
EDEM1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (602 aa)
FAM3DFamily with sequence similarity 3 member D. (223 aa)
ACSL3Acyl-CoA synthetase long chain family member 3. (720 aa)
TARDBPTAR DNA binding protein. (298 aa)
RANGAP1Ran GTPase activating protein 1. (594 aa)
ATP13A2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1173 aa)
SLC7A11Solute carrier family 7 member 11. (503 aa)
PINK1PTEN induced kinase 1. (580 aa)
RHBDF1Rhomboid 5 homolog 1. (856 aa)
RAB11FIP3RAB11 family interacting protein 3. (647 aa)
FIS1Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa)
CNSTConsortin, connexin sorting protein. (722 aa)
CIB1Calcium and integrin binding 1. (187 aa)
M3YWA8_MUSPFUncharacterized protein. (726 aa)
BAIAP3BAI1 associated protein 3. (1157 aa)
CEMIPCell migration inducing hyaluronidase 1. (1428 aa)
STXBP4Syntaxin binding protein 4. (522 aa)
GIPGastric inhibitory polypeptide. (144 aa)
GOLPH3Golgi phosphoprotein 3. (236 aa)
M3YUN0_MUSPFC1q domain-containing protein. (306 aa)
UBR5Ubiquitin protein ligase E3 component n-recognin 5. (2544 aa)
M3YUA0_MUSPFBRO1 domain-containing protein. (656 aa)
ERBB2Receptor protein-tyrosine kinase. (1260 aa)
CCL5C-C motif chemokine. (91 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (613 aa)
TFAP2ETranscription factor AP-2 epsilon. (433 aa)
SLC35D3Solute carrier family 35 member D3. (423 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (576 aa)
PRKAA1Non-specific serine/threonine protein kinase. (517 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
KRT20Keratin 20; Belongs to the intermediate filament family. (429 aa)
NF1Neurofibromin 1. (2815 aa)
M3YSH5_MUSPFUncharacterized protein. (367 aa)
GOPCPDZ domain-containing protein. (463 aa)
SH3TC2SH3 domain and tetratricopeptide repeats 2. (1289 aa)
RFX6Regulatory factor X6. (928 aa)
C1QTNF12C1q and TNF related 12. (305 aa)
SVIPSmall VCP interacting protein. (96 aa)
DNAJC27DnaJ heat shock protein family (Hsp40) member C27. (273 aa)
FKBP1BPeptidylprolyl isomerase. (209 aa)
GAPVD1GTPase activating protein and VPS9 domains 1. (1460 aa)
LLGL2LLGL scribble cell polarity complex component 2. (1022 aa)
B3GAT3Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (313 aa)
P3H1Prolyl 3-hydroxylase 1. (735 aa)
GRIPAP1GRIP1 associated protein 1. (841 aa)
TSG101Tumor susceptibility 101. (391 aa)
RBM22RNA binding motif protein 22. (420 aa)
RPH3ALRabphilin 3A like (without C2 domains). (301 aa)
DOC2BDouble C2 domain beta. (376 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (251 aa)
TREML1Triggering receptor expressed on myeloid cells like 1. (314 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (230 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (210 aa)
TOMM7Translocase of outer mitochondrial membrane 7. (55 aa)
SERGEFSecretion regulating guanine nucleotide exchange factor. (470 aa)
DMAP1DNA methyltransferase 1 associated protein 1. (468 aa)
PTPN14Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1088 aa)
MYO1CMyosin IC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1065 aa)
RHBDF2Rhomboid 5 homolog 2. (828 aa)
M3YPT2_MUSPFUBA domain-containing protein. (384 aa)
INPP5KInositol polyphosphate-5-phosphatase K. (473 aa)
MIEF1Mitochondrial elongation factor 1. (463 aa)
BIRC5Baculoviral IAP repeat containing 5. (142 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (200 aa)
HMMRHyaluronan mediated motility receptor. (711 aa)
CDK16Cyclin dependent kinase 16; Belongs to the protein kinase superfamily. (500 aa)
RSAD2Radical S-adenosyl methionine domain containing 2. (364 aa)
UBE2G2Ubiquitin conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family. (165 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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