STRINGSTRING
APLNR APLNR SRI SRI RYR1 RYR1 HTR2C HTR2C ANXA5 ANXA5 FGF2 FGF2 CCL21 CCL21 CCL19 CCL19 HRC HRC SLC8B1 SLC8B1 TPCN1 TPCN1 ITPR3 ITPR3 CHD7 CHD7 PKD2 PKD2 P2RX7 P2RX7 DDIT3 DDIT3 CASQ2 CASQ2 HTR2A HTR2A PTK2B PTK2B RYR3 RYR3 CALM1 CALM1 CYBA CYBA JPH3 JPH3 M3YAV1_MUSPF M3YAV1_MUSPF CXCL11 CXCL11 CXCL10 CXCL10 CXCL9 CXCL9 PLCG2 PLCG2 ITPR1 ITPR1 PTPN6 PTPN6 CHERP CHERP ATG5 ATG5 CAPN3 CAPN3 TRPM2 TRPM2 GP9 GP9 TRPA1 TRPA1 ITPR2 ITPR2 PTPRC PTPRC LYN LYN HTT HTT LETM1 LETM1 TRPC1 TRPC1 DHRS7C DHRS7C PRKCE PRKCE CALM2 CALM2 GP1BB GP1BB M3Z7P0_MUSPF M3Z7P0_MUSPF XCR1 XCR1 FKBP1B FKBP1B TRDN TRDN M3YU65_MUSPF M3YU65_MUSPF PDPK1 PDPK1 CEMIP CEMIP FASLG FASLG F2RL3 F2RL3 TMEM38A TMEM38A TMEM38B TMEM38B JSRP1 JSRP1 SLC25A23 SLC25A23 UBASH3B UBASH3B MCOLN3 MCOLN3 F2R F2R M3Y2G4_MUSPF M3Y2G4_MUSPF NOL3 NOL3 IBTK IBTK THY1 THY1 PRKD1 PRKD1 ERO1A ERO1A F2 F2 CXCR3 CXCR3 CALM3 CALM3 M3Y0R3_MUSPF M3Y0R3_MUSPF HTR2B HTR2B CAPN9 CAPN9 TPCN2 TPCN2 CCR5 CCR5 M3Z785_MUSPF M3Z785_MUSPF TRPV1 TRPV1 CORO1A CORO1A ABL1 ABL1 RYR2 RYR2 M3YMU3_MUSPF M3YMU3_MUSPF CD19 CD19 ANXA6 ANXA6 CASQ1 CASQ1 DRD1 DRD1 GPER1 GPER1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (380 aa)
SRISorcin. (198 aa)
RYR1Ryanodine receptor 1. (4983 aa)
HTR2C5-hydroxytryptamine receptor 2C. (458 aa)
ANXA5Annexin. (321 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
CCL21SCY domain-containing protein. (137 aa)
CCL19C-C motif chemokine. (108 aa)
HRCHistidine rich calcium binding protein. (711 aa)
SLC8B1Solute carrier family 8 member B1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (588 aa)
TPCN1Two pore segment channel 1. (861 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2609 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2522 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (915 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (594 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa)
CASQ2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (505 aa)
HTR2A5-hydroxytryptamine receptor 2A. (470 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
RYR3Ryanodine receptor 3. (4863 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (156 aa)
CYBACytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (194 aa)
JPH3Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (754 aa)
M3YAV1_MUSPFUncharacterized protein. (270 aa)
CXCL11C-X-C motif chemokine. (132 aa)
CXCL10C-X-C motif chemokine. (98 aa)
CXCL9C-X-C motif chemokine. (155 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1266 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2709 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)
CHERPCalcium homeostasis endoplasmic reticulum protein. (949 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
CAPN3Calpain 3; Belongs to the peptidase C2 family. (821 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1496 aa)
GP9Glycoprotein IX platelet. (177 aa)
TRPA1Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1117 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1298 aa)
LYNTyrosine-protein kinase. (512 aa)
HTTHuntingtin. (3018 aa)
LETM1Leucine zipper and EF-hand containing transmembrane protein 1. (718 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (743 aa)
DHRS7CDehydrogenase/reductase 7C; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (311 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa)
CALM2Calmodulin 2; Belongs to the calmodulin family. (149 aa)
GP1BBGlycoprotein Ib platelet subunit beta. (209 aa)
M3Z7P0_MUSPFLRRCT domain-containing protein. (682 aa)
XCR1X-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (331 aa)
FKBP1BPeptidylprolyl isomerase. (209 aa)
TRDNTriadin. (664 aa)
M3YU65_MUSPFC-C motif chemokine. (93 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (531 aa)
CEMIPCell migration inducing hyaluronidase 1. (1428 aa)
FASLGFas ligand; Belongs to the tumor necrosis factor family. (275 aa)
F2RL3F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. (451 aa)
TMEM38ATransmembrane protein 38A. (303 aa)
TMEM38BTransmembrane protein 38B. (291 aa)
JSRP1Junctional sarcoplasmic reticulum protein 1. (316 aa)
SLC25A23Solute carrier family 25 member 23; Belongs to the mitochondrial carrier (TC 2.A.29) family. (436 aa)
UBASH3BUbiquitin associated and SH3 domain containing B. (649 aa)
MCOLN3Mucolipin 3. (552 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (426 aa)
M3Y2G4_MUSPFUncharacterized protein. (50 aa)
NOL3Nucleolar protein 3. (217 aa)
IBTKInhibitor of Bruton tyrosine kinase. (1352 aa)
THY1Thy-1 cell surface antigen. (161 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (824 aa)
ERO1AEndoplasmic reticulum oxidoreductase 1 alpha. (468 aa)
F2Coagulation factor II, thrombin; Belongs to the peptidase S1 family. (602 aa)
CXCR3C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (368 aa)
CALM3Calmodulin 3; Belongs to the calmodulin family. (151 aa)
M3Y0R3_MUSPFUncharacterized protein. (201 aa)
HTR2B5-hydroxytryptamine receptor 2B. (481 aa)
CAPN9Calpain 9; Belongs to the peptidase C2 family. (691 aa)
TPCN2Uncharacterized protein. (746 aa)
CCR5C-C motif chemokine receptor 5 (gene/pseudogene); Belongs to the G-protein coupled receptor 1 family. (352 aa)
M3Z785_MUSPFUncharacterized protein; Belongs to the calmodulin family. (149 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1. (770 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
ABL1Tyrosine-protein kinase. (1150 aa)
RYR2Ryanodine receptor 2. (4966 aa)
M3YMU3_MUSPFMIR domain-containing protein. (78 aa)
CD19CD19 molecule. (560 aa)
ANXA6Annexin. (673 aa)
CASQ1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (402 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (359 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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