STRINGSTRING
HTR2B HTR2B MAP10 MAP10 EVI2B EVI2B KLHL9 KLHL9 RHOB RHOB NUP62 NUP62 M3Z5K9_MUSPF M3Z5K9_MUSPF SFN SFN PDGFA PDGFA RBL1 RBL1 SIRT2 SIRT2 TGFB1 TGFB1 E2F7 E2F7 FGF2 FGF2 INTU INTU PLK4 PLK4 ECT2 ECT2 BBS4 BBS4 TADA3 TADA3 FGF8 FGF8 NANOG NANOG CUL3 CUL3 MBIP MBIP RAB11FIP3 RAB11FIP3 M3YX33_MUSPF M3YX33_MUSPF AHCTF1 AHCTF1 CIB1 CIB1 PRC1 PRC1 KDF1 KDF1 BLM BLM M3YUX6_MUSPF M3YUX6_MUSPF MYO19 MYO19 SETD2 SETD2 TADA2A TADA2A CDC6 CDC6 RAB11FIP4 RAB11FIP4 PIN1 PIN1 RACGAP1 RACGAP1 INCENP INCENP GIT1 GIT1 YBX1 YBX1 E2F8 E2F8 RHOA RHOA PLK3 PLK3 CCP110 CCP110 INSC INSC PDGFB PDGFB VEGFB VEGFB ITGB1BP1 ITGB1BP1 SVIL SVIL VEGFA VEGFA SGF29 SGF29 FGF7 FGF7 PLK1 PLK1 WDR5 WDR5 CDC14A CDC14A VEGFC VEGFC PRKCE PRKCE CETN2 CETN2 M3YK20_MUSPF M3YK20_MUSPF CAT CAT M3YJA7_MUSPF M3YJA7_MUSPF ENTR1 ENTR1 PAX6 PAX6 M3YIK9_MUSPF M3YIK9_MUSPF M3YHC9_MUSPF M3YHC9_MUSPF GIPC2 GIPC2 IL1B IL1B KAT2A KAT2A SOX17 SOX17 KIF14 KIF14 CSPP1 CSPP1 M3YFG2_MUSPF M3YFG2_MUSPF BECN1 BECN1 IL1A IL1A KIF20A KIF20A PGF PGF PPBP PPBP BTC BTC TGFB3 TGFB3 EFHC1 EFHC1 PRDM15 PRDM15 KIF18B KIF18B UVRAG UVRAG ZFYVE19 ZFYVE19 CDC25B CDC25B GAREM2 GAREM2 C10orf99 C10orf99 WNT9B WNT9B AURKB AURKB M3Y9J9_MUSPF M3Y9J9_MUSPF FGF1 FGF1 SMYD5 SMYD5 PLK2 PLK2 ANKRD53 ANKRD53 M3Y7C1_MUSPF M3Y7C1_MUSPF RAB11B RAB11B TGFA TGFA ZFYVE26 ZFYVE26 FSD1L FSD1L GAREM1 GAREM1 DLL1 DLL1 M3Y687_MUSPF M3Y687_MUSPF KLHL21 KLHL21 NLRP5 NLRP5 PTCH1 PTCH1 FGF5 FGF5 PDGFD PDGFD AURKC AURKC AURKA AURKA M3Y3L0_MUSPF M3Y3L0_MUSPF PDGFC PDGFC MAP9 MAP9 IGF2 IGF2 SFRP2 SFRP2 BIRC6 BIRC6 RHOC RHOC FSD1 FSD1 THBS4 THBS4 CXCR5 CXCR5 SH3GLB1 SH3GLB1 PKN2 PKN2 M3XZV6_MUSPF M3XZV6_MUSPF FGF4 FGF4 OOEP OOEP TGFB2 TGFB2 M3XYN0_MUSPF M3XYN0_MUSPF DR1 DR1 PTN PTN HDGF HDGF GIPC3 GIPC3 DRD2 DRD2 M3XXC5_MUSPF M3XXC5_MUSPF TP63 TP63 NKX3-1 NKX3-1 RBL2 RBL2 GIPC1 GIPC1 CIT CIT M3XV19_MUSPF M3XV19_MUSPF SUSD2 SUSD2 ORC6 ORC6 VEGFD VEGFD YEATS2 YEATS2 BRCA2 BRCA2 CHMP4C CHMP4C LOC101681938 LOC101681938 KLHL13 KLHL13 MYC MYC KAT14 KAT14 RACK1 RACK1 PIK3C3 PIK3C3 TXNIP TXNIP FGF9 FGF9 RAB11A RAB11A DRD3 DRD3 KLHL34 KLHL34 FLCN FLCN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HTR2B5-hydroxytryptamine receptor 2B. (481 aa)
MAP10Microtubule associated protein 10. (848 aa)
EVI2BEcotropic viral integration site 2B. (455 aa)
KLHL9Kelch like family member 9. (617 aa)
RHOBRas homolog family member B. (196 aa)
NUP62Nucleoporin 62. (527 aa)
M3Z5K9_MUSPFGFA domain-containing protein. (261 aa)
SFN14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (255 aa)
PDGFAPlatelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa)
RBL1RB transcriptional corepressor like 1. (1066 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (412 aa)
TGFB1Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa)
E2F7E2F transcription factor 7. (899 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
INTUInturned planar cell polarity protein. (942 aa)
PLK4Polo like kinase 4. (968 aa)
ECT2Epithelial cell transforming 2. (914 aa)
BBS4Bardet-Biedl syndrome 4. (507 aa)
TADA3Transcriptional adaptor 3. (384 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (247 aa)
NANOGHomeobox domain-containing protein. (310 aa)
CUL3Cullin 3; Belongs to the cullin family. (746 aa)
MBIPMAP3K12 binding inhibitory protein 1. (344 aa)
RAB11FIP3RAB11 family interacting protein 3. (647 aa)
M3YX33_MUSPFUncharacterized protein. (191 aa)
AHCTF1AT-hook containing transcription factor 1. (2322 aa)
CIB1Calcium and integrin binding 1. (187 aa)
PRC1Protein regulator of cytokinesis 1. (563 aa)
KDF1Keratinocyte differentiation factor 1. (397 aa)
BLMBLM RecQ like helicase. (1221 aa)
M3YUX6_MUSPFUncharacterized protein. (497 aa)
MYO19Myosin XIX; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (863 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2564 aa)
TADA2ATranscriptional adapter. (443 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (558 aa)
RAB11FIP4RAB11 family interacting protein 4. (544 aa)
PIN1Peptidyl-prolyl cis-trans isomerase. (162 aa)
RACGAP1Rac GTPase activating protein 1. (631 aa)
INCENPInner centromere protein. (890 aa)
GIT1GIT ArfGAP 1. (708 aa)
YBX1Y-box binding protein 1. (330 aa)
E2F8E2F transcription factor 8. (860 aa)
RHOARas homolog family member A. (193 aa)
PLK3Serine/threonine-protein kinase PLK. (646 aa)
CCP110Centriolar coiled-coil protein 110. (967 aa)
INSCINSC spindle orientation adaptor protein. (579 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (242 aa)
VEGFBVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (188 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (200 aa)
SVILSupervillin. (2245 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (398 aa)
SGF29SAGA complex associated factor 29. (293 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
PLK1Serine/threonine-protein kinase PLK. (542 aa)
WDR5WD repeat domain 5. (334 aa)
CDC14ACell division cycle 14A. (610 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (370 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa)
CETN2Centrin 2. (178 aa)
M3YK20_MUSPFWD_REPEATS_REGION domain-containing protein. (237 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
M3YJA7_MUSPF14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (228 aa)
ENTR1Endosome associated trafficking regulator 1. (376 aa)
PAX6Paired box 6. (436 aa)
M3YIK9_MUSPFUncharacterized protein. (1827 aa)
M3YHC9_MUSPFUncharacterized protein. (903 aa)
GIPC2GIPC PDZ domain containing family member 2. (312 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (168 aa)
KAT2ALysine acetyltransferase 2A. (869 aa)
SOX17SRY-box transcription factor 17. (406 aa)
KIF14Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1662 aa)
CSPP1Centrosome and spindle pole associated protein 1. (1177 aa)
M3YFG2_MUSPFGFA domain-containing protein. (169 aa)
BECN1Beclin 1. (448 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (270 aa)
KIF20AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (887 aa)
PGFPlacental growth factor; Belongs to the PDGF/VEGF growth factor family. (170 aa)
PPBPC-X-C motif chemokine. (118 aa)
BTCBetacellulin. (185 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa)
EFHC1EF-hand domain containing 1. (688 aa)
PRDM15PR/SET domain 15. (1022 aa)
KIF18BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (866 aa)
UVRAGUV radiation resistance associated. (660 aa)
ZFYVE19Zinc finger FYVE-type containing 19. (399 aa)
CDC25BCell division cycle 25B. (515 aa)
GAREM2GRB2 associated regulator of MAPK1 subtype 2. (849 aa)
C10orf99Chromosome 10 open reading frame 99. (81 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (344 aa)
M3Y9J9_MUSPFUncharacterized protein. (553 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
SMYD5SMYD family member 5. (417 aa)
PLK2Serine/threonine-protein kinase PLK. (709 aa)
ANKRD53Ankyrin repeat domain 53. (437 aa)
M3Y7C1_MUSPFUncharacterized protein; Belongs to the AAA ATPase family. (437 aa)
RAB11BRAB11B, member RAS oncogene family. (218 aa)
TGFATransforming growth factor alpha. (158 aa)
ZFYVE26Zinc finger FYVE-type containing 26. (2539 aa)
FSD1LFibronectin type III and SPRY domain containing 1 like. (521 aa)
GAREM1GRB2 associated regulator of MAPK1 subtype 1. (753 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (602 aa)
M3Y687_MUSPFUncharacterized protein. (493 aa)
KLHL21Kelch like family member 21. (322 aa)
NLRP5NLR family pyrin domain containing 5. (1177 aa)
PTCH1Patched 1. (1386 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (265 aa)
PDGFDPlatelet derived growth factor D. (364 aa)
AURKCAurora kinase C; Belongs to the protein kinase superfamily. (307 aa)
AURKAAurora kinase A; Belongs to the protein kinase superfamily. (405 aa)
M3Y3L0_MUSPFUncharacterized protein. (99 aa)
PDGFCPlatelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa)
MAP9Microtubule associated protein 9. (645 aa)
IGF2Insulin like growth factor 2. (192 aa)
SFRP2Secreted frizzled related protein 2. (294 aa)
BIRC6Baculoviral IAP repeat containing 6. (4785 aa)
RHOCRas homolog family member C. (193 aa)
FSD1Fibronectin type III and SPRY domain containing 1. (465 aa)
THBS4Thrombospondin 4. (964 aa)
CXCR5C-X-C motif chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family. (374 aa)
SH3GLB1SH3 domain containing GRB2 like, endophilin B1. (401 aa)
PKN2Protein kinase N2. (983 aa)
M3XZV6_MUSPFFibroblast growth factor; Belongs to the heparin-binding growth factors family. (153 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
OOEPOocyte expressed protein. (149 aa)
TGFB2Transforming growth factor beta-2 proprotein; Transforming growth factor beta-2 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively. Transforming growth factor beta-2: Multifunctional protein that regulates various processes such as angiogenesis and heart development (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transfor [...] (414 aa)
M3XYN0_MUSPFUncharacterized protein. (192 aa)
DR1Down-regulator of transcription 1. (175 aa)
PTNPleiotrophin. (168 aa)
HDGFHeparin binding growth factor. (209 aa)
GIPC3GIPC PDZ domain containing family member 3. (252 aa)
DRD2D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. (443 aa)
M3XXC5_MUSPFNsp1_C domain-containing protein. (267 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (586 aa)
NKX3-1NK3 homeobox 1. (231 aa)
RBL2RB transcriptional corepressor like 2. (1139 aa)
GIPC1GIPC PDZ domain containing family member 1. (333 aa)
CITCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2069 aa)
M3XV19_MUSPFUncharacterized protein. (123 aa)
SUSD2Sushi domain containing 2. (820 aa)
ORC6Origin recognition complex subunit 6. (252 aa)
VEGFDVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa)
YEATS2YEATS domain containing 2. (1403 aa)
BRCA2BRCA2 DNA repair associated. (3466 aa)
CHMP4CCharged multivesicular body protein 4C. (237 aa)
LOC101681938Protein kinase domain-containing protein. (490 aa)
KLHL13Kelch like family member 13. (654 aa)
MYCV-myc myelocytomatosis viral oncoprotein-like protein. (453 aa)
KAT14Lysine acetyltransferase 14. (781 aa)
RACK1WD_REPEATS_REGION domain-containing protein. (317 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa)
TXNIPThioredoxin interacting protein. (391 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
RAB11ARAB11A, member RAS oncogene family. (216 aa)
DRD3Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (447 aa)
KLHL34Kelch like family member 34. (628 aa)
FLCNUDENN FLCN/SMCR8-type domain-containing protein. (579 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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