(50 nodes) Regulation of mitochondrial membrane potential network (Mustela putorius)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PID1	Phosphotyrosine interaction domain containing 1. (217 aa)
	FAM102B	Family with sequence similarity 102 member B. (329 aa)
	BOK	BCL2 family apoptosis regulator BOK. (213 aa)
	LRRK2	Leucine rich repeat kinase 2. (2527 aa)
	NDUFS1	NADH:ubiquinone oxidoreductase core subunit S1; Belongs to the complex I 75 kDa subunit family. (728 aa)
	RACK1	WD_REPEATS_REGION domain-containing protein. (317 aa)
	SPART	Spartin. (732 aa)
	P2RX7	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (594 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	BAK1	BCL2 antagonist/killer 1. (211 aa)
	PRDX3	Peroxiredoxin 3. (284 aa)
	M3XVG9_MUSPF	Uncharacterized protein. (67 aa)
	BAX	BCL2 associated X, apoptosis regulator. (192 aa)
	BCO2	Beta-carotene oxygenase 2. (579 aa)
	GCLM	Glutamate-cysteine ligase modifier subunit. (274 aa)
	M3XZQ7_MUSPF	Ubiquitin-like domain-containing protein. (311 aa)
	M3XZR5_MUSPF	RBR-type E3 ubiquitin transferase. (115 aa)
	STOX1	Storkhead box 1. (876 aa)
	STOML2	Stomatin like 2. (356 aa)
	KDR	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1355 aa)
	SLC25A33	Solute carrier family 25 member 33; Belongs to the mitochondrial carrier (TC 2.A.29) family. (320 aa)
	PARK7	Parkinsonism associated deglycase. (189 aa)
	DCN	Decorin; May affect the rate of fibrils formation. (360 aa)
	PANK2	Pantothenate kinase 2. (462 aa)
	SLC4A11	Solute carrier family 4 member 11. (856 aa)
	PPA2	Pyrophosphatase (inorganic) 2. (325 aa)
	UCP2	Uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (309 aa)
	RNF122	Ring finger protein 122. (155 aa)
	CCN6	Cellular communication network factor 6. (358 aa)
	ALOX12	Arachidonate 12-lipoxygenase, 12S type. (663 aa)
	M3YK20_MUSPF	WD_REPEATS_REGION domain-containing protein. (237 aa)
	PRELID1	PRELI domain containing 1. (220 aa)
	SLC25A36	Solute carrier family 25 member 36; Belongs to the mitochondrial carrier (TC 2.A.29) family. (311 aa)
	ABL1	Tyrosine-protein kinase. (1150 aa)
	BAD	BCL2 associated agonist of cell death. (168 aa)
	TUSC2	Tumor suppressor 2, mitochondrial calcium regulator. (110 aa)
	FAM102A	Family with sequence similarity 102 member A. (360 aa)
	PIP5KL1	Phosphatidylinositol-4-phosphate 5-kinase like 1. (394 aa)
	HEBP2	Heme binding protein 2. (204 aa)
	OPRD1	Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. (370 aa)
	M3YVX9_MUSPF	Uncharacterized protein. (198 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (488 aa)
	HSH2D	Hematopoietic SH2 domain containing. (346 aa)
	PINK1	PTEN induced kinase 1. (580 aa)
	MUL1	Mitochondrial E3 ubiquitin protein ligase 1. (352 aa)
	PPP2R3C	Protein phosphatase 2, regulatory subunit B'', gamma. (450 aa)
	MFN1	Mitofusin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (742 aa)
	AKT2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
	SRC	Tyrosine-protein kinase. (536 aa)
	MLLT11	MLLT11 transcription factor 7 cofactor. (89 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	AKT2	ENSMPUP00000002136	ENSMPUP00000017599	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.815
AKT1	AKT3	ENSMPUP00000002136	ENSMPUP00000015621	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.833
AKT1	BAD	ENSMPUP00000002136	ENSMPUP00000012854	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	BCL2 associated agonist of cell death.	0.895
AKT1	M3XVG9_MUSPF	ENSMPUP00000002136	ENSMPUP00000003069	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.864
AKT1	PPP2R3C	ENSMPUP00000002136	ENSMPUP00000016189	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Protein phosphatase 2, regulatory subunit B'', gamma.	0.830
AKT1	SRC	ENSMPUP00000002136	ENSMPUP00000017650	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.484
AKT2	AKT1	ENSMPUP00000017599	ENSMPUP00000002136	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.815
AKT2	AKT3	ENSMPUP00000017599	ENSMPUP00000015621	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.833
AKT2	BAD	ENSMPUP00000017599	ENSMPUP00000012854	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	BCL2 associated agonist of cell death.	0.895
AKT2	M3XVG9_MUSPF	ENSMPUP00000017599	ENSMPUP00000003069	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.864
AKT2	PPP2R3C	ENSMPUP00000017599	ENSMPUP00000016189	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Protein phosphatase 2, regulatory subunit B'', gamma.	0.830
AKT2	SRC	ENSMPUP00000017599	ENSMPUP00000017650	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.486
AKT3	AKT1	ENSMPUP00000015621	ENSMPUP00000002136	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.833
AKT3	AKT2	ENSMPUP00000015621	ENSMPUP00000017599	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.833
AKT3	BAD	ENSMPUP00000015621	ENSMPUP00000012854	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	BCL2 associated agonist of cell death.	0.959
AKT3	M3XVG9_MUSPF	ENSMPUP00000015621	ENSMPUP00000003069	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.898
AKT3	PPP2R3C	ENSMPUP00000015621	ENSMPUP00000016189	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Protein phosphatase 2, regulatory subunit B'', gamma.	0.847
AKT3	SRC	ENSMPUP00000015621	ENSMPUP00000017650	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.483
BAD	AKT1	ENSMPUP00000012854	ENSMPUP00000002136	BCL2 associated agonist of cell death.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.895
BAD	AKT2	ENSMPUP00000012854	ENSMPUP00000017599	BCL2 associated agonist of cell death.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.895