STRINGSTRING
SMAD7 SMAD7 PKP2 PKP2 XIRP2 XIRP2 LRP2 LRP2 MYL2 MYL2 CHD7 CHD7 M3XUF3_MUSPF M3XUF3_MUSPF M3XVU9_MUSPF M3XVU9_MUSPF MYBPC3 MYBPC3 HEG1 HEG1 M3Y355_MUSPF M3Y355_MUSPF M3Y3H1_MUSPF M3Y3H1_MUSPF ZFPM2 ZFPM2 FOXH1 FOXH1 BMP10 BMP10 M3Y4N7_MUSPF M3Y4N7_MUSPF BMP2 BMP2 M3Y4Z1_MUSPF M3Y4Z1_MUSPF MYH6 MYH6 TGFBR1 TGFBR1 EDNRA EDNRA WNT2 WNT2 TBX20 TBX20 M3YA03_MUSPF M3YA03_MUSPF M3YAH8_MUSPF M3YAH8_MUSPF DLL4 DLL4 SMAD4 SMAD4 BMPR1A BMPR1A TNNI1 TNNI1 NOTCH1 NOTCH1 NKX2-5 NKX2-5 RYR2 RYR2 PROX1 PROX1 HAND1 HAND1 ENG ENG PTCD2 PTCD2 TCAP TCAP M3YU90_MUSPF M3YU90_MUSPF MYL10 MYL10 M3YXC0_MUSPF M3YXC0_MUSPF TNNC1 TNNC1 ANKRD1 ANKRD1 TGFB1 TGFB1 MYLK2 MYLK2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMAD7Mothers against decapentaplegic homolog. (426 aa)
PKP2Plakophilin 2. (836 aa)
XIRP2Xin actin binding repeat containing 2. (3308 aa)
LRP2LDL receptor related protein 2. (4699 aa)
MYL2Myosin light chain 2. (166 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2522 aa)
M3XUF3_MUSPFMyosin_tail_1 domain-containing protein. (182 aa)
M3XVU9_MUSPFUncharacterized protein. (73 aa)
MYBPC3Myosin binding protein C, cardiac. (1272 aa)
HEG1Heart development protein with EGF like domains 1. (1278 aa)
M3Y355_MUSPFMyosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (117 aa)
M3Y3H1_MUSPFMyosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (244 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1151 aa)
FOXH1Forkhead box H1. (398 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
M3Y4N7_MUSPFUncharacterized protein. (111 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
M3Y4Z1_MUSPFMyosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (140 aa)
MYH6Myosin heavy chain 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1594 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (480 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
WNT2Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa)
TBX20T-box transcription factor 20. (446 aa)
M3YA03_MUSPFUncharacterized protein. (666 aa)
M3YAH8_MUSPFUncharacterized protein. (111 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (533 aa)
TNNI1Troponin I1, slow skeletal type. (187 aa)
NOTCH1Notch receptor 1. (2119 aa)
NKX2-5NK2 homeobox 5. (323 aa)
RYR2Ryanodine receptor 2. (4966 aa)
PROX1Prospero homeobox 1. (737 aa)
HAND1Heart and neural crest derivatives expressed 1. (215 aa)
ENGEndoglin. (653 aa)
PTCD2Pentatricopeptide repeat domain 2. (383 aa)
TCAPTitin-cap. (167 aa)
M3YU90_MUSPFMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (616 aa)
MYL10Myosin light chain 10. (167 aa)
M3YXC0_MUSPFUncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (109 aa)
TNNC1Troponin C1, slow skeletal and cardiac type. (185 aa)
ANKRD1Ankyrin repeat domain 1. (319 aa)
TGFB1Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa)
MYLK2Myosin light chain kinase 2. (699 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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