(34 nodes) Cardiac muscle cell development network (Mustela putorius)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CXADR	Uncharacterized protein. (386 aa)
	M3XLW6_MUSPF	Uncharacterized protein. (97 aa)
	NEB	Nebulin. (5858 aa)
	MAML1	Mastermind like transcriptional coactivator 1. (789 aa)
	NRAP	Nebulin related anchoring protein. (1728 aa)
	TBX5	T-box transcription factor 5. (559 aa)
	TBX3	T-box transcription factor 3. (757 aa)
	MYLK3	Myosin light chain kinase 3. (793 aa)
	ASB2	Ankyrin repeat and SOCS box containing 2. (630 aa)
	LMNA	Lamin A/C; Belongs to the intermediate filament family. (665 aa)
	M3Y280_MUSPF	Uncharacterized protein. (94 aa)
	PDGFRA	Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1087 aa)
	BMP10	Bone morphogenetic protein 10. (424 aa)
	BMPR1A	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (533 aa)
	BVES	Blood vessel epicardial substance. (360 aa)
	LRRC10B	Leucine rich repeat containing 10B. (242 aa)
	M3Z5M9_MUSPF	Uncharacterized protein. (279 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
	ALPK2	Alpha kinase 2. (2097 aa)
	MTOR	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2552 aa)
	HNRNPU	Heterogeneous nuclear ribonucleoprotein U. (592 aa)
	ALPK3	Alpha kinase 3. (1592 aa)
	TCAP	Titin-cap. (167 aa)
	ZMPSTE24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
	ATG5	Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
	CSRP3	Cysteine and glycine rich protein 3. (194 aa)
	MYO18B	Myosin XVIIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2588 aa)
	SGCD	Sarcoglycan delta. (289 aa)
	PROX1	Prospero homeobox 1. (737 aa)
	SRF	Serum response factor. (508 aa)
	ACTN2	Actinin alpha 2. (894 aa)
	NEBL	Nebulette. (1019 aa)
	FHL2	Four and a half LIM domains 2. (279 aa)
	MEF2A	Myocyte enhancer factor 2A. (416 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTN2	CSRP3	ENSMPUP00000012647	ENSMPUP00000013794	Actinin alpha 2.	Cysteine and glycine rich protein 3.	0.686
ACTN2	MYLK3	ENSMPUP00000012647	ENSMPUP00000002707	Actinin alpha 2.	Myosin light chain kinase 3.	0.514
ACTN2	MYO18B	ENSMPUP00000012647	ENSMPUP00000013536	Actinin alpha 2.	Myosin XVIIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.411
ACTN2	NEB	ENSMPUP00000012647	ENSMPUP00000000374	Actinin alpha 2.	Nebulin.	0.570
ACTN2	NEBL	ENSMPUP00000012647	ENSMPUP00000011853	Actinin alpha 2.	Nebulette.	0.530
ACTN2	NRAP	ENSMPUP00000012647	ENSMPUP00000001998	Actinin alpha 2.	Nebulin related anchoring protein.	0.490
ACTN2	TBX5	ENSMPUP00000012647	ENSMPUP00000002687	Actinin alpha 2.	T-box transcription factor 5.	0.523
ACTN2	TCAP	ENSMPUP00000012647	ENSMPUP00000014881	Actinin alpha 2.	Titin-cap.	0.639
ATG5	MTOR	ENSMPUP00000009457	ENSMPUP00000016325	Autophagy protein 5; Involved in autophagic vesicle formation.	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.527
BMP10	BMPR1A	ENSMPUP00000006259	ENSMPUP00000008777	Bone morphogenetic protein 10.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.534
BMP10	TBX5	ENSMPUP00000006259	ENSMPUP00000002687	Bone morphogenetic protein 10.	T-box transcription factor 5.	0.462
BMPR1A	BMP10	ENSMPUP00000008777	ENSMPUP00000006259	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Bone morphogenetic protein 10.	0.534
CAV3	CSRP3	ENSMPUP00000016953	ENSMPUP00000013794	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Cysteine and glycine rich protein 3.	0.561
CAV3	SGCD	ENSMPUP00000016953	ENSMPUP00000013418	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Sarcoglycan delta.	0.658
CSRP3	ACTN2	ENSMPUP00000013794	ENSMPUP00000012647	Cysteine and glycine rich protein 3.	Actinin alpha 2.	0.686
CSRP3	CAV3	ENSMPUP00000013794	ENSMPUP00000016953	Cysteine and glycine rich protein 3.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.561
CSRP3	NRAP	ENSMPUP00000013794	ENSMPUP00000001998	Cysteine and glycine rich protein 3.	Nebulin related anchoring protein.	0.579
CSRP3	TCAP	ENSMPUP00000013794	ENSMPUP00000014881	Cysteine and glycine rich protein 3.	Titin-cap.	0.556
LMNA	TCAP	ENSMPUP00000004723	ENSMPUP00000014881	Lamin A/C; Belongs to the intermediate filament family.	Titin-cap.	0.405
LMNA	ZMPSTE24	ENSMPUP00000004723	ENSMPUP00000014154	Lamin A/C; Belongs to the intermediate filament family.	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	0.598