STRINGSTRING
WNT2 WNT2 GLI1 GLI1 TBX5 TBX5 SAV1 SAV1 M3Y243_MUSPF M3Y243_MUSPF JARID2 JARID2 GATA6 GATA6 ZFPM2 ZFPM2 BMP10 BMP10 TGFBR1 TGFBR1 YAP1 YAP1 TP73 TP73 TBX20 TBX20 ERBB4 ERBB4 MEF2C MEF2C BMPR1A BMPR1A NOTCH1 NOTCH1 PIM1 PIM1 TBX2 TBX2 FGF2 FGF2 FGF9 FGF9 FGF20 FGF20 CITED2 CITED2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WNT2Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa)
GLI1GLI family zinc finger 1. (1105 aa)
TBX5T-box transcription factor 5. (559 aa)
SAV1Salvador family WW domain containing protein 1. (384 aa)
M3Y243_MUSPFzf-C5HC2 domain-containing protein. (128 aa)
JARID2Jumonji and AT-rich interaction domain containing 2. (1092 aa)
GATA6GATA binding protein 6. (482 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1151 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (480 aa)
YAP1Yes associated protein 1. (325 aa)
TP73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (710 aa)
TBX20T-box transcription factor 20. (446 aa)
ERBB4Receptor protein-tyrosine kinase. (1224 aa)
MEF2CMyocyte enhancer factor 2C. (433 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (533 aa)
NOTCH1Notch receptor 1. (2119 aa)
PIM1Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (313 aa)
TBX2T-box transcription factor 2. (679 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (273 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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