STRINGSTRING
SCN4B SCN4B KCNQ1 KCNQ1 RNF207 RNF207 CAV1 CAV1 KCNH2 KCNH2 WDR1 WDR1 FLNA FLNA ZMPSTE24 ZMPSTE24 KCNH6 KCNH6 AKAP6 AKAP6 CAV3 CAV3 M3XQH2_MUSPF M3XQH2_MUSPF SCN5A SCN5A NEDD4L NEDD4L KCNE4 KCNE4 KCNJ2 KCNJ2 KCNE3 KCNE3 KCNE2 KCNE2 KCNA5 KCNA5 GJA5 GJA5 CACNA2D1 CACNA2D1 SNTA1 SNTA1 NOS1AP NOS1AP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SCN4BSodium voltage-gated channel beta subunit 4. (228 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (590 aa)
RNF207Ring finger protein 207. (639 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
KCNH2Potassium voltage-gated channel subfamily H member 2. (1159 aa)
WDR1WD repeat domain 1. (629 aa)
FLNAFilamin A. (2647 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
KCNH6Potassium voltage-gated channel subfamily H member 6. (927 aa)
AKAP6A-kinase anchoring protein 6. (2319 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
M3XQH2_MUSPFUncharacterized protein. (130 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2016 aa)
NEDD4LNEDD4 like E3 ubiquitin protein ligase. (999 aa)
KCNE4Potassium voltage-gated channel subfamily E regulatory subunit 4. (170 aa)
KCNJ2Potassium voltage-gated channel subfamily J member 2. (427 aa)
KCNE3Potassium voltage-gated channel subfamily E regulatory subunit 3. (99 aa)
KCNE2Potassium voltage-gated channel subfamily E regulatory subunit 2. (123 aa)
KCNA5Potassium voltage-gated channel subfamily A member 5; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium- selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane (By similarity). Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA5, and possibly other family [...] (601 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1103 aa)
SNTA1Syntrophin alpha 1. (505 aa)
NOS1APNitric oxide synthase 1 adaptor protein. (700 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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