(17 nodes) Regulation of ventricular cardiac muscle cell membrane repolarization network (Mustela putorius)

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second shell of interactors

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Your Input:
	SNTA1	Syntrophin alpha 1. (505 aa)
	M3XQH2_MUSPF	Uncharacterized protein. (130 aa)
	SCN5A	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2016 aa)
	NOS1AP	Nitric oxide synthase 1 adaptor protein. (700 aa)
	SCN4B	Sodium voltage-gated channel beta subunit 4. (228 aa)
	KCNQ1	Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (590 aa)
	RNF207	Ring finger protein 207. (639 aa)
	KCNH2	Potassium voltage-gated channel subfamily H member 2. (1159 aa)
	WDR1	WD repeat domain 1. (629 aa)
	KCNH6	Potassium voltage-gated channel subfamily H member 6. (927 aa)
	ZMPSTE24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
	CACNA2D1	Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1103 aa)
	GJA5	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
	KCNE2	Potassium voltage-gated channel subfamily E regulatory subunit 2. (123 aa)
	KCNE3	Potassium voltage-gated channel subfamily E regulatory subunit 3. (99 aa)
	KCNE4	Potassium voltage-gated channel subfamily E regulatory subunit 4. (170 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CACNA2D1	KCNE3	ENSMPUP00000018178	ENSMPUP00000019405	Calcium voltage-gated channel auxiliary subunit alpha2delta 1.	Potassium voltage-gated channel subfamily E regulatory subunit 3.	0.441
CACNA2D1	KCNH2	ENSMPUP00000018178	ENSMPUP00000007505	Calcium voltage-gated channel auxiliary subunit alpha2delta 1.	Potassium voltage-gated channel subfamily H member 2.	0.488
CACNA2D1	KCNQ1	ENSMPUP00000018178	ENSMPUP00000005070	Calcium voltage-gated channel auxiliary subunit alpha2delta 1.	Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family.	0.537
CACNA2D1	SCN5A	ENSMPUP00000018178	ENSMPUP00000002553	Calcium voltage-gated channel auxiliary subunit alpha2delta 1.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.661
CAV3	KCNE2	ENSMPUP00000016953	ENSMPUP00000019101	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Potassium voltage-gated channel subfamily E regulatory subunit 2.	0.477
CAV3	KCNH2	ENSMPUP00000016953	ENSMPUP00000007505	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Potassium voltage-gated channel subfamily H member 2.	0.450
CAV3	M3XQH2_MUSPF	ENSMPUP00000016953	ENSMPUP00000001322	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Uncharacterized protein.	0.422
CAV3	SCN4B	ENSMPUP00000016953	ENSMPUP00000004411	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Sodium voltage-gated channel beta subunit 4.	0.416
CAV3	SCN5A	ENSMPUP00000016953	ENSMPUP00000002553	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.403
CAV3	SNTA1	ENSMPUP00000016953	ENSMPUP00000017721	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Syntrophin alpha 1.	0.514
GJA5	KCNE2	ENSMPUP00000018352	ENSMPUP00000019101	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Potassium voltage-gated channel subfamily E regulatory subunit 2.	0.426
GJA5	KCNH2	ENSMPUP00000018352	ENSMPUP00000007505	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Potassium voltage-gated channel subfamily H member 2.	0.422
GJA5	M3XQH2_MUSPF	ENSMPUP00000018352	ENSMPUP00000001322	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Uncharacterized protein.	0.430
GJA5	SCN5A	ENSMPUP00000018352	ENSMPUP00000002553	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.642
KCNE2	CAV3	ENSMPUP00000019101	ENSMPUP00000016953	Potassium voltage-gated channel subfamily E regulatory subunit 2.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.477
KCNE2	GJA5	ENSMPUP00000019101	ENSMPUP00000018352	Potassium voltage-gated channel subfamily E regulatory subunit 2.	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.	0.426
KCNE2	KCNE3	ENSMPUP00000019101	ENSMPUP00000019405	Potassium voltage-gated channel subfamily E regulatory subunit 2.	Potassium voltage-gated channel subfamily E regulatory subunit 3.	0.861
KCNE2	KCNE4	ENSMPUP00000019101	ENSMPUP00000019965	Potassium voltage-gated channel subfamily E regulatory subunit 2.	Potassium voltage-gated channel subfamily E regulatory subunit 4.	0.769
KCNE2	KCNH2	ENSMPUP00000019101	ENSMPUP00000007505	Potassium voltage-gated channel subfamily E regulatory subunit 2.	Potassium voltage-gated channel subfamily H member 2.	0.768
KCNE2	KCNH6	ENSMPUP00000019101	ENSMPUP00000014835	Potassium voltage-gated channel subfamily E regulatory subunit 2.	Potassium voltage-gated channel subfamily H member 6.	0.587