STRINGSTRING
TBX3 TBX3 SRC SRC TGFB1 TGFB1 PML PML BTRC BTRC PHB2 PHB2 EPHA2 EPHA2 M3YU90_MUSPF M3YU90_MUSPF CSMD2 CSMD2 DDR1 DDR1 KDM5B KDM5B ESR1 ESR1 AREG AREG LRP5 LRP5 CSF1 CSF1 CSMD1 CSMD1 M3XTZ9_MUSPF M3XTZ9_MUSPF VDR VDR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TBX3T-box transcription factor 3. (757 aa)
SRCTyrosine-protein kinase. (536 aa)
TGFB1Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa)
PMLPromyelocytic leukemia. (876 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (567 aa)
PHB2Prohibitin. (299 aa)
EPHA2EPH receptor A2. (975 aa)
M3YU90_MUSPFMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (616 aa)
CSMD2CUB and Sushi multiple domains 2. (3298 aa)
DDR1Discoidin domain receptor tyrosine kinase 1. (919 aa)
KDM5BLysine demethylase 5B. (1691 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (597 aa)
AREGAmphiregulin. (283 aa)
LRP5Uncharacterized protein. (1465 aa)
CSF1Colony stimulating factor 1. (517 aa)
CSMD1CUB and Sushi multiple domains 1. (2957 aa)
M3XTZ9_MUSPFUncharacterized protein. (207 aa)
VDRVitamin D receptor. (427 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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