(20 nodes) Lung epithelial cell differentiation network (Mustela putorius)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SAV1	Salvador family WW domain containing protein 1. (384 aa)
	NKX2-1	NK2 homeobox 1. (371 aa)
	FOXA1	Forkhead box A1. (501 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
	SOX9	SRY-box transcription factor 9. (522 aa)
	AGR2	Anterior gradient 2, protein disulphide isomerase family member. (175 aa)
	THRB	Thyroid hormone receptor beta. (461 aa)
	KRAS	KRAS proto-oncogene, GTPase. (208 aa)
	YAP1	Yes associated protein 1. (325 aa)
	TMEM38B	Transmembrane protein 38B. (291 aa)
	M3Y4E6_MUSPF	Uncharacterized protein. (160 aa)
	GATA6	GATA binding protein 6. (482 aa)
	FNDC3B	Fibronectin type III domain containing 3B. (1206 aa)
	CREB1	cAMP responsive element binding protein 1. (341 aa)
	NKX2-2	NK2 homeobox 2. (273 aa)
	RBBP9	RB binding protein 9, serine hydrolase. (243 aa)
	SPDEF	SAM pointed domain containing ETS transcription factor. (335 aa)
	NFIB	Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (570 aa)
	HOXA5	Homeobox A5. (270 aa)
	AIMP2	Aminoacyl tRNA synthetase complex interacting multifunctional protein 2. (320 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGR2	FOXA1	ENSMPUP00000013875	ENSMPUP00000016151	Anterior gradient 2, protein disulphide isomerase family member.	Forkhead box A1.	0.403
AGR2	SPDEF	ENSMPUP00000013875	ENSMPUP00000003134	Anterior gradient 2, protein disulphide isomerase family member.	SAM pointed domain containing ETS transcription factor.	0.570
FGF10	KRAS	ENSMPUP00000014301	ENSMPUP00000010217	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	KRAS proto-oncogene, GTPase.	0.634
FGF10	NKX2-1	ENSMPUP00000014301	ENSMPUP00000016159	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	NK2 homeobox 1.	0.509
FGF10	SOX9	ENSMPUP00000014301	ENSMPUP00000014195	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	SRY-box transcription factor 9.	0.532
FOXA1	AGR2	ENSMPUP00000016151	ENSMPUP00000013875	Forkhead box A1.	Anterior gradient 2, protein disulphide isomerase family member.	0.403
FOXA1	GATA6	ENSMPUP00000016151	ENSMPUP00000005576	Forkhead box A1.	GATA binding protein 6.	0.816
FOXA1	NKX2-1	ENSMPUP00000016151	ENSMPUP00000016159	Forkhead box A1.	NK2 homeobox 1.	0.596
FOXA1	NKX2-2	ENSMPUP00000016151	ENSMPUP00000001184	Forkhead box A1.	NK2 homeobox 2.	0.427
GATA6	FOXA1	ENSMPUP00000005576	ENSMPUP00000016151	GATA binding protein 6.	Forkhead box A1.	0.816
GATA6	NKX2-1	ENSMPUP00000005576	ENSMPUP00000016159	GATA binding protein 6.	NK2 homeobox 1.	0.473
GATA6	SOX9	ENSMPUP00000005576	ENSMPUP00000014195	GATA binding protein 6.	SRY-box transcription factor 9.	0.561
KRAS	FGF10	ENSMPUP00000010217	ENSMPUP00000014301	KRAS proto-oncogene, GTPase.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.634
KRAS	YAP1	ENSMPUP00000010217	ENSMPUP00000007150	KRAS proto-oncogene, GTPase.	Yes associated protein 1.	0.462
NKX2-1	FGF10	ENSMPUP00000016159	ENSMPUP00000014301	NK2 homeobox 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.509
NKX2-1	FOXA1	ENSMPUP00000016159	ENSMPUP00000016151	NK2 homeobox 1.	Forkhead box A1.	0.596
NKX2-1	GATA6	ENSMPUP00000016159	ENSMPUP00000005576	NK2 homeobox 1.	GATA binding protein 6.	0.473
NKX2-1	SOX9	ENSMPUP00000016159	ENSMPUP00000014195	NK2 homeobox 1.	SRY-box transcription factor 9.	0.499
NKX2-2	FOXA1	ENSMPUP00000001184	ENSMPUP00000016151	NK2 homeobox 2.	Forkhead box A1.	0.427
SAV1	YAP1	ENSMPUP00000005083	ENSMPUP00000007150	Salvador family WW domain containing protein 1.	Yes associated protein 1.	0.833