STRINGSTRING
TULP3 TULP3 SMAD3 SMAD3 PRICKLE1 PRICKLE1 VDR VDR EDN1 EDN1 LRP2 LRP2 FZD3 FZD3 EXT1 EXT1 M3XPU3_MUSPF M3XPU3_MUSPF GZF1 GZF1 MTSS1 MTSS1 NOTCH2 NOTCH2 M3XQT3_MUSPF M3XQT3_MUSPF ZIC3 ZIC3 SHANK3 SHANK3 STARD13 STARD13 HAND2 HAND2 BRD2 BRD2 KDM2B KDM2B CC2D2A CC2D2A TCTN1 TCTN1 PKD2 PKD2 PLXNB2 PLXNB2 FUZ FUZ GBX2 GBX2 DVL3 DVL3 CELSR1 CELSR1 M3XTZ9_MUSPF M3XTZ9_MUSPF CSMD1 CSMD1 TEAD2 TEAD2 TBX3 TBX3 ARL13B ARL13B IRX3 IRX3 ASB2 ASB2 NKX3-1 NKX3-1 OPA1 OPA1 HES1 HES1 RASIP1 RASIP1 CSF1 CSF1 DLG1 DLG1 DLG5 DLG5 GLMN GLMN NODAL NODAL LRP5 LRP5 MED12 MED12 HOXA5 HOXA5 LMO4 LMO4 HOXA11 HOXA11 M3Y0D8_MUSPF M3Y0D8_MUSPF LAMA1 LAMA1 SOX4 SOX4 M3Y0V5_MUSPF M3Y0V5_MUSPF FKBP14 FKBP14 ARHGAP35 ARHGAP35 KDR KDR HECTD1 HECTD1 CITED1 CITED1 BCL10 BCL10 BMP4 BMP4 SFRP2 SFRP2 ILK ILK GREB1L GREB1L MIB1 MIB1 NFATC4 NFATC4 PRKACB PRKACB M3Y377_MUSPF M3Y377_MUSPF VASP VASP SMO SMO LIAS LIAS RARG RARG FOXH1 FOXH1 M3Y4E6_MUSPF M3Y4E6_MUSPF BMP2 BMP2 HIF1A HIF1A HHIP HHIP MTHFD1 MTHFD1 PTCH1 PTCH1 ESRP2 ESRP2 EDNRA EDNRA CTSZ CTSZ DLL1 DLL1 PLEKHH1 PLEKHH1 MET MET YAP1 YAP1 MMP14 MMP14 ADAMTS16 ADAMTS16 IRX1 IRX1 MEGF8 MEGF8 IRX2 IRX2 ACVRL1 ACVRL1 TBX20 TBX20 FGF1 FGF1 MEF2C MEF2C DLG2 DLG2 SCRIB SCRIB WNT9B WNT9B SHROOM3 SHROOM3 FOXF1 FOXF1 SEC24B SEC24B M3YB95_MUSPF M3YB95_MUSPF ST14 ST14 SPINT1 SPINT1 DLL4 DLL4 SMAD4 SMAD4 WNT11 WNT11 LRRC1 LRRC1 LEF1 LEF1 DNAAF1 DNAAF1 NPNT NPNT GDF2 GDF2 PKHD1 PKHD1 TGFB3 TGFB3 AREG AREG CCDC103 CCDC103 C2CD3 C2CD3 PAX8 PAX8 M3YE59_MUSPF M3YE59_MUSPF NPHP3 NPHP3 KLHL3 KLHL3 IFT57 IFT57 WNK4 WNK4 M3YFG7_MUSPF M3YFG7_MUSPF RDH10 RDH10 KRAS KRAS MTHFD1L MTHFD1L ESR1 ESR1 DVL2 DVL2 SOX17 SOX17 KAT2A KAT2A EYA1 EYA1 M3YI82_MUSPF M3YI82_MUSPF KDM5B KDM5B LGR4 LGR4 WT1 WT1 NOTCH1 NOTCH1 SEMA4C SEMA4C CTNNB1 CTNNB1 DDR1 DDR1 TRAF6 TRAF6 CCDC40 CCDC40 TSC1 TSC1 TBX6 TBX6 ABL1 ABL1 RYR2 RYR2 GPC3 GPC3 KDM6A KDM6A MICAL2 MICAL2 M3YNS9_MUSPF M3YNS9_MUSPF SRF SRF PTK7 PTK7 TRIM71 TRIM71 GREB1 GREB1 HAND1 HAND1 ENG ENG MST1 MST1 OSR1 OSR1 GDF7 GDF7 TIE1 TIE1 DAG1 DAG1 SOSTDC1 SOSTDC1 LHX2 LHX2 SOX9 SOX9 DVL1 DVL1 FGF10 FGF10 GNA13 GNA13 WNT1 WNT1 TCF21 TCF21 AHI1 AHI1 GDNF GDNF CSMD2 CSMD2 TCAP TCAP M3YU90_MUSPF M3YU90_MUSPF SETD2 SETD2 LHX1 LHX1 CLUAP1 CLUAP1 CTHRC1 CTHRC1 TBX2 TBX2 M3YUX6_MUSPF M3YUX6_MUSPF STK3 STK3 MKS1 MKS1 PKD1 PKD1 CTSH CTSH IL16 IL16 TMEM59L TMEM59L PHACTR4 PHACTR4 KIF26B KIF26B CLIC4 CLIC4 GRHL3 GRHL3 SOX8 SOX8 LUZP1 LUZP1 PAK1 PAK1 FOXA1 FOXA1 NKX2-1 NKX2-1 EPHA2 EPHA2 MTHFR MTHFR GATA3 GATA3 WNT6 WNT6 IHH IHH EPHA4 EPHA4 SLIT2 SLIT2 PHB2 PHB2 M3YZI9_MUSPF M3YZI9_MUSPF SUFU SUFU BTRC BTRC LBX1 LBX1 LZTS2 LZTS2 BBS4 BBS4 PLXND1 PLXND1 PML PML RET RET FGF2 FGF2 LGR5 LGR5 SALL4 SALL4 STK4 STK4 TGFB1 TGFB1 IFT52 IFT52 SRC SRC SPINT2 SPINT2 CECR2 CECR2 RALA RALA GLI3 GLI3 COBL COBL CCM2 CCM2 SEMA3E SEMA3E M3Z3T6_MUSPF M3Z3T6_MUSPF SPRY2 SPRY2 LOC101676600 LOC101676600 APLNR APLNR CITED2 CITED2 SPRY1 SPRY1 FZD2 FZD2 M3Z7C0_MUSPF M3Z7C0_MUSPF GREM1 GREM1 COMMD5 COMMD5 TACSTD2 TACSTD2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TULP3Tubby-like protein; Belongs to the TUB family. (462 aa)
SMAD3Mothers against decapentaplegic homolog. (414 aa)
PRICKLE1Prickle planar cell polarity protein 1. (832 aa)
VDRVitamin D receptor. (427 aa)
EDN1Endothelin 1. (202 aa)
LRP2LDL receptor related protein 2. (4699 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
M3XPU3_MUSPFUncharacterized protein; Belongs to the protein kinase superfamily. (361 aa)
GZF1GDNF inducible zinc finger protein 1. (806 aa)
MTSS1MTSS I-BAR domain containing 1. (687 aa)
NOTCH2Notch receptor 2. (2471 aa)
M3XQT3_MUSPFUncharacterized protein. (1208 aa)
ZIC3Zic family member 3. (473 aa)
SHANK3SH3 and multiple ankyrin repeat domains 3. (1712 aa)
STARD13StAR related lipid transfer domain containing 13. (1124 aa)
HAND2Heart and neural crest derivatives expressed 2. (208 aa)
BRD2Bromodomain containing 2. (803 aa)
KDM2BLysine demethylase 2B. (1310 aa)
CC2D2ACoiled-coil and C2 domain containing 2A. (1621 aa)
TCTN1Tectonic family member 1. (589 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (915 aa)
PLXNB2Plexin B2. (1841 aa)
FUZFuzzy planar cell polarity protein. (392 aa)
GBX2Gastrulation brain homeobox 2. (325 aa)
DVL3Dishevelled segment polarity protein 3. (718 aa)
CELSR1Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (2735 aa)
M3XTZ9_MUSPFUncharacterized protein. (207 aa)
CSMD1CUB and Sushi multiple domains 1. (2957 aa)
TEAD2TEA domain transcription factor 2. (545 aa)
TBX3T-box transcription factor 3. (757 aa)
ARL13BADP ribosylation factor like GTPase 13B. (430 aa)
IRX3Iroquois homeobox 3. (502 aa)
ASB2Ankyrin repeat and SOCS box containing 2. (630 aa)
NKX3-1NK3 homeobox 1. (231 aa)
OPA1OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (1015 aa)
HES1Hes family bHLH transcription factor 1. (283 aa)
RASIP1Ras interacting protein 1. (966 aa)
CSF1Colony stimulating factor 1. (517 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (927 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1922 aa)
GLMNGlomulin, FKBP associated protein. (600 aa)
NODALNodal growth differentiation factor. (348 aa)
LRP5Uncharacterized protein. (1465 aa)
MED12Mediator complex subunit 12. (2168 aa)
HOXA5Homeobox A5. (270 aa)
LMO4LIM domain only 4. (165 aa)
HOXA11Homeobox A11. (269 aa)
M3Y0D8_MUSPFUncharacterized protein. (356 aa)
LAMA1Laminin subunit alpha 1. (3086 aa)
SOX4SRY-box transcription factor 4. (269 aa)
M3Y0V5_MUSPFPodocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family. (514 aa)
FKBP14Peptidylprolyl isomerase. (230 aa)
ARHGAP35Rho GTPase activating protein 35. (1500 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1355 aa)
HECTD1HECT domain E3 ubiquitin protein ligase 1. (2610 aa)
CITED1Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (201 aa)
BCL10BCL10 immune signaling adaptor. (241 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
SFRP2Secreted frizzled related protein 2. (294 aa)
ILKIntegrin linked kinase. (452 aa)
GREB1LGREB1 like retinoic acid receptor coactivator. (1971 aa)
MIB1Mindbomb E3 ubiquitin protein ligase 1. (1006 aa)
NFATC4Nuclear factor of activated T cells 4. (831 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa)
M3Y377_MUSPFNTR domain-containing protein. (233 aa)
VASPVasodilator stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (382 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (790 aa)
LIASLipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (362 aa)
RARGRetinoic acid receptor gamma. (458 aa)
FOXH1Forkhead box H1. (398 aa)
M3Y4E6_MUSPFUncharacterized protein. (160 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (824 aa)
HHIPHedgehog interacting protein. (700 aa)
MTHFD1Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1. (935 aa)
PTCH1Patched 1. (1386 aa)
ESRP2Epithelial splicing regulatory protein 2. (661 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
CTSZCathepsin Z; Belongs to the peptidase C1 family. (300 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (602 aa)
PLEKHH1Pleckstrin homology, MyTH4 and FERM domain containing H1. (1364 aa)
METHepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1540 aa)
YAP1Yes associated protein 1. (325 aa)
MMP14Matrix metallopeptidase 14. (582 aa)
ADAMTS16ADAM metallopeptidase with thrombospondin type 1 motif 16. (1169 aa)
IRX1Iroquois homeobox 1. (319 aa)
MEGF8Multiple EGF like domains 8. (2396 aa)
IRX2Iroquois homeobox 2. (391 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
TBX20T-box transcription factor 20. (446 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
MEF2CMyocyte enhancer factor 2C. (433 aa)
DLG2Uncharacterized protein. (833 aa)
SCRIBScribble planar cell polarity protein. (1523 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
SHROOM3Shroom family member 3. (1723 aa)
FOXF1Forkhead box F1. (321 aa)
SEC24BSEC24 homolog B, COPII coat complex component. (1285 aa)
M3YB95_MUSPFUncharacterized protein. (696 aa)
ST14Suppression of tumorigenicity 14. (859 aa)
SPINT1Serine peptidase inhibitor, Kunitz type 1. (521 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
LRRC1Leucine rich repeat containing 1. (524 aa)
LEF1Lymphoid enhancer binding factor 1. (400 aa)
DNAAF1Dynein assembly factor 1, axonemal. (657 aa)
NPNTNephronectin. (597 aa)
GDF2Growth differentiation factor 2. (429 aa)
PKHD1PKHD1 ciliary IPT domain containing fibrocystin/polyductin. (4056 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa)
AREGAmphiregulin. (283 aa)
CCDC103Coiled-coil domain containing 103. (240 aa)
C2CD3C2 domain containing 3 centriole elongation regulator. (2334 aa)
PAX8Paired box 8. (462 aa)
M3YE59_MUSPFHH_signal domain-containing protein. (290 aa)
NPHP3TPR_REGION domain-containing protein. (1331 aa)
KLHL3Kelch like family member 3. (601 aa)
IFT57Intraflagellar transport 57. (429 aa)
WNK4WNK lysine deficient protein kinase 4. (1242 aa)
M3YFG7_MUSPFUncharacterized protein. (135 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
KRASKRAS proto-oncogene, GTPase. (208 aa)
MTHFD1LMethylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (918 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (597 aa)
DVL2Dishevelled segment polarity protein 2. (734 aa)
SOX17SRY-box transcription factor 17. (406 aa)
KAT2ALysine acetyltransferase 2A. (869 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (621 aa)
M3YI82_MUSPFCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)
KDM5BLysine demethylase 5B. (1691 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (890 aa)
WT1WT1 transcription factor. (433 aa)
NOTCH1Notch receptor 1. (2119 aa)
SEMA4CSemaphorin 4C; Belongs to the semaphorin family. (867 aa)
CTNNB1Catenin beta 1. (781 aa)
DDR1Discoidin domain receptor tyrosine kinase 1. (919 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
CCDC40Coiled-coil domain containing 40. (1142 aa)
TSC1TSC complex subunit 1. (1165 aa)
TBX6T-box transcription factor 6. (436 aa)
ABL1Tyrosine-protein kinase. (1150 aa)
RYR2Ryanodine receptor 2. (4966 aa)
GPC3Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (580 aa)
KDM6ALysine demethylase 6A. (1419 aa)
MICAL2Microtubule associated monooxygenase, calponin and LIM domain containing 2. (1124 aa)
M3YNS9_MUSPFBMERB domain-containing protein. (703 aa)
SRFSerum response factor. (508 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1070 aa)
TRIM71Tripartite motif containing 71. (514 aa)
GREB1Uncharacterized protein. (1955 aa)
HAND1Heart and neural crest derivatives expressed 1. (215 aa)
ENGEndoglin. (653 aa)
MST1Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. (711 aa)
OSR1Odd-skipped related transcription factor 1. (267 aa)
GDF7Growth differentiation factor 7. (382 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (994 aa)
DAG1Dystroglycan 1. (891 aa)
SOSTDC1Sclerostin domain containing 1. (209 aa)
LHX2LIM homeobox 2. (406 aa)
SOX9SRY-box transcription factor 9. (522 aa)
DVL1Dishevelled segment polarity protein 1. (691 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
GNA13G protein subunit alpha 13. (284 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (340 aa)
TCF21Transcription factor 21. (179 aa)
AHI1Abelson helper integration site 1. (1171 aa)
GDNFGlial cell derived neurotrophic factor. (211 aa)
CSMD2CUB and Sushi multiple domains 2. (3298 aa)
TCAPTitin-cap. (167 aa)
M3YU90_MUSPFMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (616 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2564 aa)
LHX1LIM homeobox 1. (406 aa)
CLUAP1Clusterin associated protein 1. (437 aa)
CTHRC1Collagen triple helix repeat containing 1. (282 aa)
TBX2T-box transcription factor 2. (679 aa)
M3YUX6_MUSPFUncharacterized protein. (497 aa)
STK3Serine/threonine kinase 3. (418 aa)
MKS1MKS transition zone complex subunit 1. (559 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4230 aa)
CTSHCathepsin H; Belongs to the peptidase C1 family. (335 aa)
IL16Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. (1376 aa)
TMEM59LTransmembrane protein 59 like. (351 aa)
PHACTR4Phosphatase and actin regulator. (708 aa)
KIF26BKinesin family member 26B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1878 aa)
CLIC4Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (253 aa)
GRHL3Grainyhead like transcription factor 3. (602 aa)
SOX8SRY-box transcription factor 8. (377 aa)
LUZP1Leucine zipper protein 1. (1073 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
FOXA1Forkhead box A1. (501 aa)
NKX2-1NK2 homeobox 1. (371 aa)
EPHA2EPH receptor A2. (975 aa)
MTHFRMethylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (654 aa)
GATA3GATA binding protein 3. (444 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
IHHIndian hedgehog signaling molecule. (384 aa)
EPHA4EPH receptor A4. (986 aa)
SLIT2Slit guidance ligand 2. (1539 aa)
PHB2Prohibitin. (299 aa)
M3YZI9_MUSPFHomeobox domain-containing protein. (197 aa)
SUFUSuppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (484 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (567 aa)
LBX1Ladybird homeobox 1. (281 aa)
LZTS2Leucine zipper putative tumor suppressor 2; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta- catenin. (670 aa)
BBS4Bardet-Biedl syndrome 4. (507 aa)
PLXND1Plexin D1. (1746 aa)
PMLPromyelocytic leukemia. (876 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1028 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
LGR5Leucine rich repeat containing G protein-coupled receptor 5. (907 aa)
SALL4Spalt like transcription factor 4. (1097 aa)
STK4Serine/threonine kinase 4. (487 aa)
TGFB1Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa)
IFT52Intraflagellar transport 52. (446 aa)
SRCTyrosine-protein kinase. (536 aa)
SPINT2Serine peptidase inhibitor, Kunitz type, 2. (252 aa)
CECR2CECR2 histone acetyl-lysine reader. (1368 aa)
RALARAS like proto-oncogene A. (206 aa)
GLI3GLI family zinc finger 3. (1585 aa)
COBLCordon-bleu WH2 repeat protein. (1316 aa)
CCM2CCM2 scaffold protein. (426 aa)
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (775 aa)
M3Z3T6_MUSPFHomeobox domain-containing protein. (184 aa)
SPRY2Sprouty RTK signaling antagonist 2. (315 aa)
LOC101676600Homeobox domain-containing protein. (185 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (380 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (273 aa)
SPRY1Sprouty-like protein 1, antagonist of FGF signaling. (319 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (550 aa)
M3Z7C0_MUSPFCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)
GREM1Gremlin. (184 aa)
COMMD5COMM domain containing 5. (224 aa)
TACSTD2Tumor associated calcium signal transducer 2. (316 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
Server load: low (36%) [HD]