(36 nodes) Regulation of morphogenesis of a branching structure network (Mustela putorius)

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Predicted Interactions

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Your Input:
	SIRT6	Sirtuin 6. (359 aa)
	PHB2	Prohibitin. (299 aa)
	SOX8	SRY-box transcription factor 8. (377 aa)
	HOXB7	Homeobox B7. (217 aa)
	LHX1	LIM homeobox 1. (406 aa)
	GDNF	Glial cell derived neurotrophic factor. (211 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
	SOX9	SRY-box transcription factor 9. (522 aa)
	HOXD13	Homeobox D13. (341 aa)
	ABL1	Tyrosine-protein kinase. (1150 aa)
	FGF7	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
	SIX2	SIX homeobox 2. (296 aa)
	TNF	Tumor necrosis factor alpha; Belongs to the tumor necrosis factor family. (233 aa)
	LGR4	Leucine rich repeat containing G protein-coupled receptor 4. (890 aa)
	SULF1	Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (867 aa)
	RTN4	Reticulon. (986 aa)
	ESR1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (597 aa)
	PAX8	Paired box 8. (462 aa)
	TGFB3	Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa)
	WNT2	Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa)
	SIX4	SIX homeobox 4. (455 aa)
	SIX1	SIX homeobox 1. (284 aa)
	SMO	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (790 aa)
	M3Y377_MUSPF	NTR domain-containing protein. (233 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	WNT2B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
	AGT	Angiotensinogen; Belongs to the serpin family. (477 aa)
	BTBD7	BTB domain containing 7. (1127 aa)
	MAP3K13	Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (966 aa)
	LRRK2	Leucine rich repeat kinase 2. (2527 aa)
	GREM1	Gremlin. (184 aa)
	TACSTD2	Tumor associated calcium signal transducer 2. (316 aa)
	TGFB1	Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa)
	HGF	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (725 aa)
	FKBPL	FKBP prolyl isomerase like. (349 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGT	TGFB1	ENSMPUP00000004588	ENSMPUP00000017540	Angiotensinogen; Belongs to the serpin family.	Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...]	0.520
BMP4	FGF10	ENSMPUP00000005423	ENSMPUP00000014301	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.818
BMP4	FGF7	ENSMPUP00000005423	ENSMPUP00000012246	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.629
BMP4	GDNF	ENSMPUP00000005423	ENSMPUP00000014777	Bone morphogenetic protein 4.	Glial cell derived neurotrophic factor.	0.445
BMP4	GREM1	ENSMPUP00000005423	ENSMPUP00000019709	Bone morphogenetic protein 4.	Gremlin.	0.894
BMP4	HGF	ENSMPUP00000005423	ENSMPUP00000018177	Bone morphogenetic protein 4.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.433
BMP4	SOX9	ENSMPUP00000005423	ENSMPUP00000014195	Bone morphogenetic protein 4.	SRY-box transcription factor 9.	0.589
ESR1	PHB2	ENSMPUP00000010404	ENSMPUP00000016660	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Prohibitin.	0.735
ESR1	TGFB1	ENSMPUP00000010404	ENSMPUP00000017540	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...]	0.531
ESR1	TNF	ENSMPUP00000010404	ENSMPUP00000011297	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Tumor necrosis factor alpha; Belongs to the tumor necrosis factor family.	0.531
FGF10	BMP4	ENSMPUP00000014301	ENSMPUP00000005423	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Bone morphogenetic protein 4.	0.818
FGF10	FGF7	ENSMPUP00000014301	ENSMPUP00000012246	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.410
FGF10	GDNF	ENSMPUP00000014301	ENSMPUP00000014777	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Glial cell derived neurotrophic factor.	0.602
FGF10	HGF	ENSMPUP00000014301	ENSMPUP00000018177	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.701
FGF10	SOX9	ENSMPUP00000014301	ENSMPUP00000014195	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	SRY-box transcription factor 9.	0.532
FGF10	TGFB1	ENSMPUP00000014301	ENSMPUP00000017540	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...]	0.656
FGF10	TNF	ENSMPUP00000014301	ENSMPUP00000011297	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Tumor necrosis factor alpha; Belongs to the tumor necrosis factor family.	0.511
FGF7	BMP4	ENSMPUP00000012246	ENSMPUP00000005423	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Bone morphogenetic protein 4.	0.629
FGF7	FGF10	ENSMPUP00000012246	ENSMPUP00000014301	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.410
FGF7	GDNF	ENSMPUP00000012246	ENSMPUP00000014777	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Glial cell derived neurotrophic factor.	0.631