STRINGSTRING
SOCS1 SOCS1 UBE2K UBE2K DCST1 DCST1 HIF1A HIF1A M3Y5L5_MUSPF M3Y5L5_MUSPF CDC37 CDC37 F2RL1 F2RL1 NOL3 NOL3 TXK TXK HIPK1 HIPK1 M3Y193_MUSPF M3Y193_MUSPF VRK2 VRK2 PARP9 PARP9 ECM1 ECM1 FADD FADD M3XZR5_MUSPF M3XZR5_MUSPF M3XZQ7_MUSPF M3XZQ7_MUSPF PIAS4 PIAS4 PTPN2 PTPN2 DDX58 DDX58 NLRC5 NLRC5 APOA1 APOA1 GFI1 GFI1 CACTIN CACTIN C1QTNF4 C1QTNF4 CSF1 CSF1 ADIPOQ ADIPOQ CYLD CYLD PALM3 PALM3 PELI3 PELI3 IRF3 IRF3 CXCR4 CXCR4 M3XSY8_MUSPF M3XSY8_MUSPF M3XSY7_MUSPF M3XSY7_MUSPF TLR4 TLR4 STAP1 STAP1 STAT2 STAT2 XIAP XIAP M3XP26_MUSPF M3XP26_MUSPF EDN1 EDN1 IFIH1 IFIH1 RIPK1 RIPK1 M3XM81_MUSPF M3XM81_MUSPF MAPK7 MAPK7 OTUD4 OTUD4 M3Y653_MUSPF M3Y653_MUSPF SHARPIN SHARPIN ADAR ADAR CAV1 CAV1 LSM14A LSM14A OTOP1 OTOP1 BIRC7 BIRC7 NLRP6 NLRP6 SIGIRR SIGIRR MAVS MAVS IRF7 IRF7 IRAK1 IRAK1 STING1 STING1 GAS6 GAS6 IL1RN IL1RN IL36RN IL36RN M3YE36_MUSPF M3YE36_MUSPF YTHDF3 YTHDF3 IL7 IL7 PTPRC PTPRC NKIRAS2 NKIRAS2 RIPK2 RIPK2 TRAF2 TRAF2 HPX HPX OTULIN OTULIN PYCARD PYCARD DHX9 DHX9 NR1H4 NR1H4 TRIM44 TRIM44 IKBKE IKBKE NKIRAS1 NKIRAS1 IL1R2 IL1R2 PAFAH1B1 PAFAH1B1 SLIT3 SLIT3 TRAIP TRAIP SPHK1 SPHK1 TREM2 TREM2 TREML1 TREML1 CD74 CD74 ISG15 ISG15 M3YRW9_MUSPF M3YRW9_MUSPF RFFL RFFL M3YU90_MUSPF M3YU90_MUSPF YTHDF2 YTHDF2 MUL1 MUL1 M3YXN1_MUSPF M3YXN1_MUSPF PADI2 PADI2 TTLL12 TTLL12 SLIT2 SLIT2 TNFRSF1A TNFRSF1A IRAK2 IRAK2 TBK1 TBK1 SPATA2 SPATA2 AXL AXL SAMHD1 SAMHD1 M3Z266_MUSPF M3Z266_MUSPF CNOT7 CNOT7 M3Z434_MUSPF M3Z434_MUSPF TRIM32 TRIM32 TREX1 TREX1 TRIM56 TRIM56
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SOCS1Suppressor of cytokine signaling 1. (216 aa)
UBE2KUbiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family. (269 aa)
DCST1DC-STAMP domain containing 1. (625 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (824 aa)
M3Y5L5_MUSPFUncharacterized protein. (444 aa)
CDC37Cell division cycle 37. (380 aa)
F2RL1F2R like trypsin receptor 1. (397 aa)
NOL3Nucleolar protein 3. (217 aa)
TXKTyrosine-protein kinase. (551 aa)
HIPK1Homeodomain interacting protein kinase 1. (1210 aa)
M3Y193_MUSPFC2 domain-containing protein. (500 aa)
VRK2VRK serine/threonine kinase 2. (496 aa)
PARP9Poly [ADP-ribose] polymerase. (995 aa)
ECM1Extracellular matrix protein 1. (564 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (216 aa)
M3XZR5_MUSPFRBR-type E3 ubiquitin transferase. (115 aa)
M3XZQ7_MUSPFUbiquitin-like domain-containing protein. (311 aa)
PIAS4Protein inhibitor of activated STAT 4. (514 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (388 aa)
DDX58DExD/H-box helicase 58. (937 aa)
NLRC5NLR family CARD domain containing 5. (1868 aa)
APOA1Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family. (323 aa)
GFI1Growth factor independent 1 transcriptional repressor. (386 aa)
CACTINCactin, spliceosome C complex subunit. (752 aa)
C1QTNF4C1q and TNF related 4. (272 aa)
CSF1Colony stimulating factor 1. (517 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (244 aa)
CYLDCYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (953 aa)
PALM3Paralemmin 3. (627 aa)
PELI3E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (445 aa)
IRF3Interferon regulatory factor 3. (421 aa)
CXCR4C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (353 aa)
M3XSY8_MUSPFUncharacterized protein. (300 aa)
M3XSY7_MUSPFUncharacterized protein. (242 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (833 aa)
STAP1Signal transducing adaptor family member 1. (287 aa)
STAT2Signal transducer and activator of transcription. (848 aa)
XIAPX-linked inhibitor of apoptosis. (497 aa)
M3XP26_MUSPFUncharacterized protein. (265 aa)
EDN1Endothelin 1. (202 aa)
IFIH1Interferon induced with helicase C domain 1. (1027 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (646 aa)
M3XM81_MUSPFUncharacterized protein; Belongs to the MT-A70-like family. (582 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
OTUD4OTU deubiquitinase 4. (1111 aa)
M3Y653_MUSPFProtein kinase domain-containing protein. (212 aa)
SHARPINSHANK associated RH domain interactor. (378 aa)
ADARAdenosine deaminase RNA specific. (1166 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
LSM14ALSM14A mRNA processing body assembly factor. (463 aa)
OTOP1Otopetrin 1. (616 aa)
BIRC7Baculoviral IAP repeat containing 7. (300 aa)
NLRP6NLR family pyrin domain containing 6. (948 aa)
SIGIRRSingle Ig and TIR domain containing. (410 aa)
MAVSMitochondrial antiviral signaling protein. (524 aa)
IRF7Interferon regulatory factor 7. (473 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (696 aa)
STING1Transmembrane protein 173. (378 aa)
GAS6Growth arrest specific 6. (541 aa)
IL1RNInterleukin-1. (158 aa)
IL36RNInterleukin-1. (156 aa)
M3YE36_MUSPFUncharacterized protein. (77 aa)
YTHDF3YTH N6-methyladenosine RNA binding protein 3. (585 aa)
IL7Interleukin 7. (158 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1298 aa)
NKIRAS2NFKB inhibitor interacting Ras like 2. (191 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (569 aa)
HPXHemopexin. (463 aa)
OTULINOTU deubiquitinase with linear linkage specificity. (433 aa)
PYCARDPYD and CARD domain containing. (193 aa)
DHX9DExH-box helicase 9. (1200 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (472 aa)
TRIM44Tripartite motif-containing 44. (344 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (719 aa)
NKIRAS1NFKB inhibitor interacting Ras like 1. (192 aa)
IL1R2Interleukin 1 receptor type 2. (414 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
SLIT3Slit guidance ligand 3. (1391 aa)
TRAIPTRAF interacting protein. (469 aa)
SPHK1Sphingosine kinase 1. (386 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (230 aa)
TREML1Triggering receptor expressed on myeloid cells like 1. (314 aa)
CD74CD74 molecule. (279 aa)
ISG15ISG15 ubiquitin like modifier. (184 aa)
M3YRW9_MUSPFIGv domain-containing protein. (315 aa)
RFFLRing finger and FYVE like domain containing E3 ubiquitin protein ligase. (374 aa)
M3YU90_MUSPFMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (616 aa)
YTHDF2YTH N6-methyladenosine RNA binding protein 2. (580 aa)
MUL1Mitochondrial E3 ubiquitin protein ligase 1. (352 aa)
M3YXN1_MUSPFUncharacterized protein. (506 aa)
PADI2Peptidyl arginine deiminase 2. (665 aa)
TTLL12Tubulin tyrosine ligase like 12. (580 aa)
SLIT2Slit guidance ligand 2. (1539 aa)
TNFRSF1ATNF receptor superfamily member 1A. (501 aa)
IRAK2Interleukin 1 receptor associated kinase 2. (580 aa)
TBK1TANK-binding kinase 1. (729 aa)
SPATA2Spermatogenesis associated 2. (446 aa)
AXLAXL receptor tyrosine kinase. (887 aa)
SAMHD1SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1. (626 aa)
M3Z266_MUSPFC2 domain-containing protein. (537 aa)
CNOT7CCR4-NOT transcription complex subunit 7. (285 aa)
M3Z434_MUSPFUncharacterized protein; Belongs to the MT-A70-like family. (570 aa)
TRIM32Tripartite motif containing 32. (673 aa)
TREX1Three prime repair exonuclease 1. (313 aa)
TRIM56Tripartite motif containing 56. (771 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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