STRINGSTRING
GCNT1 GCNT1 ASXL1 ASXL1 FGF2 FGF2 LZTS2 LZTS2 WNT6 WNT6 GATA3 GATA3 LRRK2 LRRK2 M3XPU3_MUSPF M3XPU3_MUSPF GZF1 GZF1 PKD2 PKD2 WWTR1 WWTR1 SALL1 SALL1 IRX3 IRX3 HES1 HES1 DLG1 DLG1 HOXA11 HOXA11 M3Y0D8_MUSPF M3Y0D8_MUSPF BMP4 BMP4 ILK ILK GREB1L GREB1L SMO SMO BMP2 BMP2 SIX1 SIX1 PTCH1 PTCH1 FRAS1 FRAS1 ADAMTS16 ADAMTS16 IRX1 IRX1 IRX2 IRX2 ERBB4 ERBB4 FGF1 FGF1 DLG2 DLG2 WNT9B WNT9B SMAD4 SMAD4 WNT11 WNT11 NPNT NPNT PPP3CA PPP3CA PAX8 PAX8 NPHP3 NPHP3 KLHL3 KLHL3 WNK4 WNK4 EYA1 EYA1 CALB1 CALB1 SOX8 SOX8 LGR4 LGR4 WT1 WT1 SIX2 SIX2 GPC3 GPC3 FOXJ1 FOXJ1 GREB1 GREB1 OSR1 OSR1 ZMPSTE24 ZMPSTE24 SOX9 SOX9 FGF10 FGF10 WNT1 WNT1 TCF21 TCF21 AHI1 AHI1 GDNF GDNF LHX1 LHX1 PKD1 PKD1 TMEM59L TMEM59L KIF26B KIF26B TACSTD2 TACSTD2 COMMD5 COMMD5 GREM1 GREM1 GCNT3 GCNT3 GCNT4 GCNT4 GLI3 GLI3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GCNT1Glucosaminyl (N-acetyl) transferase 1. (428 aa)
ASXL1ASXL transcriptional regulator 1. (1517 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
LZTS2Leucine zipper putative tumor suppressor 2; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta- catenin. (670 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
GATA3GATA binding protein 3. (444 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
M3XPU3_MUSPFUncharacterized protein; Belongs to the protein kinase superfamily. (361 aa)
GZF1GDNF inducible zinc finger protein 1. (806 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (915 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
SALL1Spalt like transcription factor 1. (1337 aa)
IRX3Iroquois homeobox 3. (502 aa)
HES1Hes family bHLH transcription factor 1. (283 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (927 aa)
HOXA11Homeobox A11. (269 aa)
M3Y0D8_MUSPFUncharacterized protein. (356 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
ILKIntegrin linked kinase. (452 aa)
GREB1LGREB1 like retinoic acid receptor coactivator. (1971 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (790 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
SIX1SIX homeobox 1. (284 aa)
PTCH1Patched 1. (1386 aa)
FRAS1Fraser extracellular matrix complex subunit 1. (4016 aa)
ADAMTS16ADAM metallopeptidase with thrombospondin type 1 motif 16. (1169 aa)
IRX1Iroquois homeobox 1. (319 aa)
IRX2Iroquois homeobox 2. (391 aa)
ERBB4Receptor protein-tyrosine kinase. (1224 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
DLG2Uncharacterized protein. (833 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
NPNTNephronectin. (597 aa)
PPP3CASerine/threonine-protein phosphatase. (461 aa)
PAX8Paired box 8. (462 aa)
NPHP3TPR_REGION domain-containing protein. (1331 aa)
KLHL3Kelch like family member 3. (601 aa)
WNK4WNK lysine deficient protein kinase 4. (1242 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (621 aa)
CALB1Calbindin 1. (261 aa)
SOX8SRY-box transcription factor 8. (377 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (890 aa)
WT1WT1 transcription factor. (433 aa)
SIX2SIX homeobox 2. (296 aa)
GPC3Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (580 aa)
FOXJ1Forkhead box J1. (421 aa)
GREB1Uncharacterized protein. (1955 aa)
OSR1Odd-skipped related transcription factor 1. (267 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
SOX9SRY-box transcription factor 9. (522 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (340 aa)
TCF21Transcription factor 21. (179 aa)
AHI1Abelson helper integration site 1. (1171 aa)
GDNFGlial cell derived neurotrophic factor. (211 aa)
LHX1LIM homeobox 1. (406 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4230 aa)
TMEM59LTransmembrane protein 59 like. (351 aa)
KIF26BKinesin family member 26B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1878 aa)
TACSTD2Tumor associated calcium signal transducer 2. (316 aa)
COMMD5COMM domain containing 5. (224 aa)
GREM1Gremlin. (184 aa)
GCNT3Glucosaminyl (N-acetyl) transferase 3, mucin type. (438 aa)
GCNT4Glucosaminyl (N-acetyl) transferase 4. (453 aa)
GLI3GLI family zinc finger 3. (1585 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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