(23 nodes) Positive regulation of cartilage development network (Mustela putorius)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

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Your Input:
	SOX9	SRY-box transcription factor 9. (522 aa)
	M3YZE5_MUSPF	Uncharacterized protein. (85 aa)
	ZNF219	Zinc finger protein 219. (715 aa)
	SMAD3	Mothers against decapentaplegic homolog. (414 aa)
	SMAD7	Mothers against decapentaplegic homolog. (426 aa)
	BMPR1B	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (514 aa)
	LOXL2	Lysyl oxidase like 2. (772 aa)
	BMP1	Metalloendopeptidase. (983 aa)
	ZBTB16	Zinc finger and BTB domain containing 16. (673 aa)
	HOXA11	Homeobox A11. (269 aa)
	GDF5	Growth differentiation factor 5. (500 aa)
	CCN1	Cellular communication network factor 1. (382 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	BMP10	Bone morphogenetic protein 10. (424 aa)
	BMP2	Bone morphogenetic protein 2. (395 aa)
	SMAD1	Mothers against decapentaplegic homolog. (465 aa)
	GDF6	Growth differentiation factor 6. (434 aa)
	PKDCC	Protein kinase domain containing, cytoplasmic. (294 aa)
	GDF2	Growth differentiation factor 2. (429 aa)
	RUNX2	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (507 aa)
	GLI3	GLI family zinc finger 3. (1585 aa)
	FGF18	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
	SOX6	SRY-box transcription factor 6. (814 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP1	BMP2	ENSMPUP00000003639	ENSMPUP00000006323	Metalloendopeptidase.	Bone morphogenetic protein 2.	0.412
BMP1	BMP4	ENSMPUP00000003639	ENSMPUP00000005423	Metalloendopeptidase.	Bone morphogenetic protein 4.	0.514
BMP1	LOXL2	ENSMPUP00000003639	ENSMPUP00000003418	Metalloendopeptidase.	Lysyl oxidase like 2.	0.416
BMP10	BMP4	ENSMPUP00000006259	ENSMPUP00000005423	Bone morphogenetic protein 10.	Bone morphogenetic protein 4.	0.573
BMP10	BMPR1B	ENSMPUP00000006259	ENSMPUP00000002076	Bone morphogenetic protein 10.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.532
BMP10	GDF2	ENSMPUP00000006259	ENSMPUP00000008940	Bone morphogenetic protein 10.	Growth differentiation factor 2.	0.840
BMP10	SMAD3	ENSMPUP00000006259	ENSMPUP00000000302	Bone morphogenetic protein 10.	Mothers against decapentaplegic homolog.	0.587
BMP2	BMP1	ENSMPUP00000006323	ENSMPUP00000003639	Bone morphogenetic protein 2.	Metalloendopeptidase.	0.412
BMP2	BMP4	ENSMPUP00000006323	ENSMPUP00000005423	Bone morphogenetic protein 2.	Bone morphogenetic protein 4.	0.935
BMP2	BMPR1B	ENSMPUP00000006323	ENSMPUP00000002076	Bone morphogenetic protein 2.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.992
BMP2	FGF18	ENSMPUP00000006323	ENSMPUP00000012757	Bone morphogenetic protein 2.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.642
BMP2	GDF5	ENSMPUP00000006323	ENSMPUP00000017688	Bone morphogenetic protein 2.	Growth differentiation factor 5.	0.494
BMP2	RUNX2	ENSMPUP00000006323	ENSMPUP00000012414	Bone morphogenetic protein 2.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.842
BMP2	SMAD1	ENSMPUP00000006323	ENSMPUP00000006812	Bone morphogenetic protein 2.	Mothers against decapentaplegic homolog.	0.805
BMP2	SMAD3	ENSMPUP00000006323	ENSMPUP00000000302	Bone morphogenetic protein 2.	Mothers against decapentaplegic homolog.	0.585
BMP2	SMAD7	ENSMPUP00000006323	ENSMPUP00000000838	Bone morphogenetic protein 2.	Mothers against decapentaplegic homolog.	0.715
BMP2	SOX9	ENSMPUP00000006323	ENSMPUP00000014195	Bone morphogenetic protein 2.	SRY-box transcription factor 9.	0.573
BMP4	BMP1	ENSMPUP00000005423	ENSMPUP00000003639	Bone morphogenetic protein 4.	Metalloendopeptidase.	0.514
BMP4	BMP10	ENSMPUP00000005423	ENSMPUP00000006259	Bone morphogenetic protein 4.	Bone morphogenetic protein 10.	0.573
BMP4	BMP2	ENSMPUP00000005423	ENSMPUP00000006323	Bone morphogenetic protein 4.	Bone morphogenetic protein 2.	0.935