STRINGSTRING
BCAS3 BCAS3 MED13 MED13 ZBTB8A ZBTB8A HDAC1 HDAC1 CDK5RAP3 CDK5RAP3 E4F1 E4F1 ARNT2 ARNT2 NR0B2 NR0B2 ARID1A ARID1A KDM1A KDM1A HSPB1 HSPB1 MLXIPL MLXIPL GTF2I GTF2I PADI2 PADI2 NKX2-1 NKX2-1 NFKBIA NFKBIA PSMA6 PSMA6 SRARP SRARP SPEN SPEN GATA3 GATA3 MAD2L2 MAD2L2 EP300 EP300 BUD31 BUD31 RNF25 RNF25 AIP AIP TRIM24 TRIM24 UBXN7 UBXN7 HIRA HIRA HIPK2 HIPK2 MYOCD MYOCD HES1 HES1 CRKL CRKL BBS2 BBS2 NKX3-1 NKX3-1 KAT6B KAT6B M3XVR3_MUSPF M3XVR3_MUSPF GSC GSC M3XVG7_MUSPF M3XVG7_MUSPF M3XVG1_MUSPF M3XVG1_MUSPF BBS1 BBS1 PKN1 PKN1 SMARCB1 SMARCB1 BRMS1 BRMS1 LOC106003337 LOC106003337 M3XV15_MUSPF M3XV15_MUSPF TBX3 TBX3 TBX5 TBX5 M3XUB3_MUSPF M3XUB3_MUSPF NR0B1 NR0B1 DDX54 DDX54 DAXX DAXX GBX2 GBX2 MED25 MED25 DNAAF4 DNAAF4 TAF7L TAF7L M3XSQ6_MUSPF M3XSQ6_MUSPF M3XSG3_MUSPF M3XSG3_MUSPF TCF7L2 TCF7L2 NR1H2 NR1H2 HAND2 HAND2 HEY1 HEY1 DDIT3 DDIT3 M3XRV6_MUSPF M3XRV6_MUSPF GATA4 GATA4 PRAME PRAME MED4 MED4 RB1 RB1 NOTCH2 NOTCH2 PRMT2 PRMT2 TRIB1 TRIB1 RNF6 RNF6 MED30 MED30 PIAS2 PIAS2 M3XNT8_MUSPF M3XNT8_MUSPF TRIP4 TRIP4 CREB1 CREB1 NR4A2 NR4A2 VDR VDR SMAD3 SMAD3 NIF3L1 NIF3L1 M3XM17_MUSPF M3XM17_MUSPF M3XLW6_MUSPF M3XLW6_MUSPF CTDP1 CTDP1 IWS1 IWS1 PPARGC1A PPARGC1A PDCD11 PDCD11 CHD4 CHD4 LDB1 LDB1 M3YZU1_MUSPF M3YZU1_MUSPF TMF1 TMF1 FOXP1 FOXP1 BHLHE40 BHLHE40 ANKRD2 ANKRD2 MMS19 MMS19 TADA3 TADA3 BBS4 BBS4 ANKRD1 ANKRD1 SIN3A SIN3A BBS7 BBS7 BBS10 BBS10 GRIP1 GRIP1 M3Z1E7_MUSPF M3Z1E7_MUSPF NCOA3 NCOA3 STK4 STK4 HNF4A HNF4A M3Z266_MUSPF M3Z266_MUSPF ACTN4 ACTN4 NCOA6 NCOA6 M3Z2E6_MUSPF M3Z2E6_MUSPF ASXL1 ASXL1 LATS1 LATS1 PPID PPID ENSMPUP00000018030 ENSMPUP00000018030 MED4-2 MED4-2 CITED2 CITED2 NRIP1 NRIP1 NHLH2 NHLH2 NHLH1 NHLH1 TOB2 TOB2 M3Z7C0_MUSPF M3Z7C0_MUSPF TAF7 TAF7 LOC106003906 LOC106003906 JUN JUN PARK7 PARK7 FBP1 FBP1 KEAP1 KEAP1 NR4A3 NR4A3 DLL1 DLL1 FAF1 FAF1 MDFIC MDFIC FIZ1 FIZ1 TP73 TP73 WWP2 WWP2 M3Y7Z9_MUSPF M3Y7Z9_MUSPF TAF4 TAF4 NR4A1 NR4A1 IFRD1 IFRD1 TBX20 TBX20 RNF14 RNF14 MEF2C MEF2C TCF3 TCF3 ANKRD42 ANKRD42 TTC8 TTC8 HDAC3 HDAC3 M3YA03_MUSPF M3YA03_MUSPF GSK3B GSK3B NR1I2 NR1I2 PITX2 PITX2 ETS2 ETS2 ETS1 ETS1 GTF2A1 GTF2A1 PRPF6 PRPF6 SNW1 SNW1 MTDH MTDH SMAD4 SMAD4 DDRGK1 DDRGK1 LEF1 LEF1 ARID5A ARID5A SMARCD3 SMARCD3 TP53 TP53 STING1 STING1 FOS FOS KDM3A KDM3A M3YCX9_MUSPF M3YCX9_MUSPF MED16 MED16 HDAC5 HDAC5 TACC1 TACC1 BRD8 BRD8 M3YEN4_MUSPF M3YEN4_MUSPF PITX1 PITX1 STRN STRN DUSP26 DUSP26 NCOR1 NCOR1 TP53BP1 TP53BP1 HDAC2 HDAC2 MLX MLX M3YG16_MUSPF M3YG16_MUSPF ESR1 ESR1 SOX17 SOX17 TRIM68 TRIM68 STAT3 STAT3 AR AR STAT5B STAT5B POU1F1 POU1F1 M3YGT2_MUSPF M3YGT2_MUSPF NCOA2 NCOA2 MED17 MED17 MEF2A MEF2A TAF6 TAF6 EGR2 EGR2 NRBF2 NRBF2 M3YI82_MUSPF M3YI82_MUSPF CTBP1 CTBP1 TGFB1I1 TGFB1I1 KAT8 KAT8 DHX9 DHX9 CTNNB1 CTNNB1 NR1H4 NR1H4 RELA RELA LHX3 LHX3 KLHL40 KLHL40 M3YKB9_MUSPF M3YKB9_MUSPF DCAF1 DCAF1 SIRT1 SIRT1 EPAS1 EPAS1 CRY1 CRY1 RXRA RXRA PRKCB PRKCB NSD1 NSD1 GFI1B GFI1B TBX6 TBX6 NKX2-5 NKX2-5 YWHAH YWHAH IFRD2 IFRD2 SRF SRF ARNTL ARNTL M3YPM9_MUSPF M3YPM9_MUSPF ELK1 ELK1 PROX1 PROX1 DMAP1 DMAP1 MYOD1 MYOD1 HAND1 HAND1 TRIB2 TRIB2 GATA1 GATA1 GTF2H1 GTF2H1 MTA2 MTA2 SP3 SP3 M3YRA0_MUSPF M3YRA0_MUSPF ATF2 ATF2 NCOA1 NCOA1 DNMT3A DNMT3A FOXP3 FOXP3 M3YRV1_MUSPF M3YRV1_MUSPF PPARGC1B PPARGC1B ZNF366 ZNF366 HEYL HEYL M3YSW1_MUSPF M3YSW1_MUSPF HIF1A HIF1A MKKS MKKS SLC30A9 SLC30A9 TAF4B TAF4B C1D C1D DACT1 DACT1 FOXH1 FOXH1 RARG RARG ZFPM2 ZFPM2 NFKBID NFKBID CRY2 CRY2 KAT6A KAT6A RBBP8 RBBP8 GATA6 GATA6 M3Y280_MUSPF M3Y280_MUSPF BCL10 BCL10 M3Y193_MUSPF M3Y193_MUSPF M3Y0T6_MUSPF M3Y0T6_MUSPF HCLS1 HCLS1 CNOT1 CNOT1 GTF2B GTF2B NR1H3 NR1H3 FAM162A FAM162A PARP9 PARP9 DTX3L DTX3L REST REST ZBTB7A ZBTB7A MED12 MED12 PARP1 PARP1 M3XZP3_MUSPF M3XZP3_MUSPF CRX CRX PTPN2 PTPN2 ARNT ARNT NCOA7 NCOA7 WIPI1 WIPI1 M3YT25_MUSPF M3YT25_MUSPF M3YT91_MUSPF M3YT91_MUSPF TCF21 TCF21 MEF2D MEF2D LRIF1 LRIF1 TP53BP2 TP53BP2 THRAP3 THRAP3 MED24 MED24 M3YU90_MUSPF M3YU90_MUSPF CREBBP CREBBP M3YUH7_MUSPF M3YUH7_MUSPF M3YUH8_MUSPF M3YUH8_MUSPF M3YUJ9_MUSPF M3YUJ9_MUSPF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BCAS3BCAS3 microtubule associated cell migration factor. (835 aa)
MED13Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2042 aa)
ZBTB8AZinc finger and BTB domain containing 8A. (441 aa)
HDAC1Histone deacetylase 1. (482 aa)
CDK5RAP3CDK5 regulatory subunit associated protein 3. (504 aa)
E4F1E4F transcription factor 1. (788 aa)
ARNT2Aryl hydrocarbon receptor nuclear translocator 2. (728 aa)
NR0B2Nuclear receptor subfamily 0 group B member 2. (279 aa)
ARID1AAT-rich interaction domain 1A. (2036 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (874 aa)
HSPB1Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (207 aa)
MLXIPLMLX interacting protein like. (857 aa)
GTF2IGeneral transcription factor IIi. (979 aa)
PADI2Peptidyl arginine deiminase 2. (665 aa)
NKX2-1NK2 homeobox 1. (371 aa)
NFKBIANFKB inhibitor alpha. (314 aa)
PSMA6Proteasome subunit alpha type. (228 aa)
SRARPSteroid receptor associated and regulated protein. (153 aa)
SPENSpen family transcriptional repressor. (3614 aa)
GATA3GATA binding protein 3. (444 aa)
MAD2L2Mitotic arrest deficient 2 like 2. (211 aa)
EP300E1A binding protein p300. (2425 aa)
BUD31BUD31 homolog. (144 aa)
RNF25Ring finger protein 25. (459 aa)
AIPPeptidylprolyl isomerase. (330 aa)
TRIM24Tripartite motif containing 24. (961 aa)
UBXN7UBX domain protein 7. (519 aa)
HIRAProtein HIRA; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (1016 aa)
HIPK2Homeodomain interacting protein kinase 2. (1165 aa)
MYOCDMyocardin. (980 aa)
HES1Hes family bHLH transcription factor 1. (283 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
BBS2Bardet-Biedl syndrome 2 protein homolog. (721 aa)
NKX3-1NK3 homeobox 1. (231 aa)
KAT6BHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2074 aa)
M3XVR3_MUSPFCOMM domain-containing protein. (161 aa)
GSCGoosecoid homeobox. (256 aa)
M3XVG7_MUSPFUncharacterized protein. (205 aa)
M3XVG1_MUSPFHelicase C-terminal domain-containing protein. (106 aa)
BBS1BBS1 domain-containing protein. (593 aa)
PKN1Protein kinase N1. (950 aa)
SMARCB1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (376 aa)
BRMS1BRMS1 transcriptional repressor and anoikis regulator. (246 aa)
LOC106003337Uncharacterized protein. (1924 aa)
M3XV15_MUSPFTACC_C domain-containing protein. (944 aa)
TBX3T-box transcription factor 3. (757 aa)
TBX5T-box transcription factor 5. (559 aa)
M3XUB3_MUSPFUncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (445 aa)
NR0B1Nuclear receptor subfamily 0 group B member 1. (474 aa)
DDX54ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. (879 aa)
DAXXDeath domain associated protein. (779 aa)
GBX2Gastrulation brain homeobox 2. (325 aa)
MED25Mediator complex subunit 25. (836 aa)
DNAAF4Dynein axonemal assembly factor 4. (420 aa)
TAF7LTATA-box binding protein associated factor 7 like. (472 aa)
M3XSQ6_MUSPFUncharacterized protein. (468 aa)
M3XSG3_MUSPFCTNNB1_binding domain-containing protein. (169 aa)
TCF7L2Transcription factor 7 like 2. (514 aa)
NR1H2Nuclear receptor subfamily 1 group H member 2. (460 aa)
HAND2Heart and neural crest derivatives expressed 2. (208 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa)
M3XRV6_MUSPFUncharacterized protein. (351 aa)
GATA4GATA binding protein 4. (442 aa)
PRAMEPreferentially expressed antigen in melanoma. (508 aa)
MED4Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (269 aa)
RB1RB transcriptional corepressor 1. (948 aa)
NOTCH2Notch receptor 2. (2471 aa)
PRMT2Protein arginine methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (457 aa)
TRIB1Tribbles pseudokinase 1. (372 aa)
RNF6Ring finger protein 6. (683 aa)
MED30Mediator complex subunit 30. (178 aa)
PIAS2Protein inhibitor of activated STAT 2. (719 aa)
M3XNT8_MUSPFUncharacterized protein. (544 aa)
TRIP4Thyroid hormone receptor interactor 4. (581 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
NR4A2Nuclear receptor subfamily 4 group A member 2. (598 aa)
VDRVitamin D receptor. (427 aa)
SMAD3Mothers against decapentaplegic homolog. (414 aa)
NIF3L1NIF3-like protein 1; May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation. (376 aa)
M3XM17_MUSPFUncharacterized protein. (208 aa)
M3XLW6_MUSPFUncharacterized protein. (97 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (759 aa)
IWS1Interacts with SUPT6H, CTD assembly factor 1. (846 aa)
PPARGC1APPARG coactivator 1 alpha. (796 aa)
PDCD11Programmed cell death 11. (1870 aa)
CHD4Uncharacterized protein. (1912 aa)
LDB1LIM domain binding 1. (411 aa)
M3YZU1_MUSPFJmjC domain-containing protein. (343 aa)
TMF1TATA element modulatory factor 1. (1088 aa)
FOXP1Forkhead box P1. (676 aa)
BHLHE40Basic helix-loop-helix family member e40. (412 aa)
ANKRD2Ankyrin repeat domain 2. (335 aa)
MMS19MMS19 homolog, cytosolic iron-sulfur assembly component. (1029 aa)
TADA3Transcriptional adaptor 3. (384 aa)
BBS4Bardet-Biedl syndrome 4. (507 aa)
ANKRD1Ankyrin repeat domain 1. (319 aa)
SIN3ASIN3 transcription regulator family member A. (1550 aa)
BBS7Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. (715 aa)
BBS10Bardet-Biedl syndrome 10. (713 aa)
GRIP1Glutamate receptor interacting protein 1. (1156 aa)
M3Z1E7_MUSPFUncharacterized protein. (109 aa)
NCOA3Nuclear receptor coactivator. (1416 aa)
STK4Serine/threonine kinase 4. (487 aa)
HNF4AHepatocyte nuclear factor 4 alpha. (443 aa)
M3Z266_MUSPFC2 domain-containing protein. (537 aa)
ACTN4Actinin alpha 4. (882 aa)
NCOA6Nuclear receptor coactivator 6. (1966 aa)
M3Z2E6_MUSPFCOMM domain-containing protein. (181 aa)
ASXL1ASXL transcriptional regulator 1. (1517 aa)
LATS1Large tumor suppressor kinase 1. (1127 aa)
PPIDPeptidylprolyl isomerase D. (370 aa)
ENSMPUP00000018030annotation not available (113 aa)
MED4-2Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (270 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (273 aa)
NRIP1Nuclear receptor interacting protein 1. (1156 aa)
NHLH2Nescient helix-loop-helix 2. (135 aa)
NHLH1Nescient helix-loop-helix 1. (133 aa)
TOB2Transducer of ERBB2, 2. (339 aa)
M3Z7C0_MUSPFCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)
TAF7TATA-box binding protein associated factor 7. (364 aa)
LOC106003906JmjC domain-containing protein. (349 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
FBP1Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (338 aa)
KEAP1Kelch like ECH associated protein 1. (620 aa)
NR4A3Nuclear receptor subfamily 4 group A member 3. (638 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (602 aa)
FAF1Fas associated factor 1. (640 aa)
MDFICMyoD family inhibitor domain containing. (243 aa)
FIZ1FLT3 interacting zinc finger 1. (571 aa)
TP73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (710 aa)
WWP2E3 ubiquitin-protein ligase. (872 aa)
M3Y7Z9_MUSPFUncharacterized protein. (283 aa)
TAF4TATA-box binding protein associated factor 4. (627 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1. (598 aa)
IFRD1Interferon related developmental regulator 1. (450 aa)
TBX20T-box transcription factor 20. (446 aa)
RNF14RBR-type E3 ubiquitin transferase. (474 aa)
MEF2CMyocyte enhancer factor 2C. (433 aa)
TCF3Transcription factor 3. (652 aa)
ANKRD42Ankyrin repeat domain 42. (348 aa)
TTC8Tetratricopeptide repeat domain 8. (590 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (430 aa)
M3YA03_MUSPFUncharacterized protein. (666 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (420 aa)
NR1I2Nuclear receptor subfamily 1 group I member 2. (324 aa)
PITX2Homeobox protein. (317 aa)
ETS2Protein C-ets-2; Transcription factor; Belongs to the ETS family. (469 aa)
ETS1ETS proto-oncogene 1, transcription factor. (443 aa)
GTF2A1General transcription factor IIA subunit 1. (376 aa)
PRPF6Pre-mRNA processing factor 6. (842 aa)
SNW1SNW domain containing 1. (536 aa)
MTDHMetadherin. (627 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
DDRGK1DDRGK domain containing 1. (315 aa)
LEF1Lymphoid enhancer binding factor 1. (400 aa)
ARID5AAT-rich interaction domain 5A. (646 aa)
SMARCD3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (441 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (375 aa)
STING1Transmembrane protein 173. (378 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (446 aa)
KDM3ALysine demethylase 3A. (1324 aa)
M3YCX9_MUSPFUncharacterized protein; Belongs to the DEAD box helicase family. (671 aa)
MED16Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (829 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1091 aa)
TACC1Transforming acidic coiled-coil containing protein 1. (772 aa)
BRD8Bromodomain containing 8. (951 aa)
M3YEN4_MUSPFBZIP domain-containing protein. (358 aa)
PITX1Homeobox protein. (290 aa)
STRNStriatin. (808 aa)
DUSP26Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (211 aa)
NCOR1Nuclear receptor corepressor 1. (2510 aa)
TP53BP1Tumor protein p53 binding protein 1. (1969 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (469 aa)
MLXMAX dimerization protein MLX. (286 aa)
M3YG16_MUSPFBHLH domain-containing protein. (137 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (597 aa)
SOX17SRY-box transcription factor 17. (406 aa)
TRIM68Tripartite motif containing 68. (485 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
ARAndrogen receptor. (892 aa)
STAT5BSignal transducer and activator of transcription. (691 aa)
POU1F1POU domain protein. (357 aa)
M3YGT2_MUSPFUncharacterized protein. (219 aa)
NCOA2DUF1518 domain-containing protein. (1226 aa)
MED17Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (651 aa)
MEF2AMyocyte enhancer factor 2A. (416 aa)
TAF6TATA-box binding protein associated factor 6. (678 aa)
EGR2Early growth response 2. (485 aa)
NRBF2Nuclear receptor binding factor 2. (286 aa)
M3YI82_MUSPFCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)
CTBP1C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (429 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (470 aa)
KAT8Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (461 aa)
DHX9DExH-box helicase 9. (1200 aa)
CTNNB1Catenin beta 1. (781 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (472 aa)
RELARELA proto-oncogene, NF-kB subunit. (511 aa)
LHX3LIM homeobox 3. (407 aa)
KLHL40Kelch like family member 40. (624 aa)
M3YKB9_MUSPFUncharacterized protein. (1910 aa)
DCAF1DDB1 and CUL4 associated factor 1. (1522 aa)
SIRT1Sirtuin 1. (557 aa)
EPAS1Endothelial PAS domain protein 1. (868 aa)
CRY1Cryptochrome circadian regulator 1. (587 aa)
RXRARetinoid X receptor alpha. (548 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (577 aa)
NSD1Nuclear receptor binding SET domain protein 1. (2701 aa)
GFI1BGrowth factor independent 1B transcriptional repressor. (327 aa)
TBX6T-box transcription factor 6. (436 aa)
NKX2-5NK2 homeobox 5. (323 aa)
YWHAHTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (246 aa)
IFRD2Interferon-related developmental regulator 2. (441 aa)
SRFSerum response factor. (508 aa)
ARNTLAryl hydrocarbon receptor nuclear translocator like. (626 aa)
M3YPM9_MUSPFBZIP domain-containing protein. (351 aa)
ELK1ETS transcription factor ELK1. (435 aa)
PROX1Prospero homeobox 1. (737 aa)
DMAP1DNA methyltransferase 1 associated protein 1. (468 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
HAND1Heart and neural crest derivatives expressed 1. (215 aa)
TRIB2Tribbles pseudokinase 2. (343 aa)
GATA1GATA binding protein 1. (414 aa)
GTF2H1General transcription factor IIH subunit 1. (547 aa)
MTA2Metastasis associated 1 family member 2. (622 aa)
SP3Sp3 transcription factor. (695 aa)
M3YRA0_MUSPFUncharacterized protein. (848 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
NCOA1Nuclear receptor coactivator. (1399 aa)
DNMT3ADNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (909 aa)
FOXP3Forkhead box P3. (433 aa)
M3YRV1_MUSPFUncharacterized protein. (286 aa)
PPARGC1BPPARG coactivator 1 beta. (1027 aa)
ZNF366Zinc finger protein 366. (659 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (328 aa)
M3YSW1_MUSPFBHLH domain-containing protein. (111 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (824 aa)
MKKSMcKusick-Kaufman syndrome. (467 aa)
SLC30A9Solute carrier family 30 member 9. (612 aa)
TAF4BTATA-box binding protein associated factor 4b. (866 aa)
C1DC1D nuclear receptor corepressor. (141 aa)
DACT1Dishevelled binding antagonist of beta catenin 1. (759 aa)
FOXH1Forkhead box H1. (398 aa)
RARGRetinoic acid receptor gamma. (458 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1151 aa)
NFKBIDNFKB inhibitor delta. (328 aa)
CRY2Cryptochrome circadian regulator 2. (594 aa)
KAT6AHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (1754 aa)
RBBP8RB binding protein 8, endonuclease. (897 aa)
GATA6GATA binding protein 6. (482 aa)
M3Y280_MUSPFUncharacterized protein. (94 aa)
BCL10BCL10 immune signaling adaptor. (241 aa)
M3Y193_MUSPFC2 domain-containing protein. (500 aa)
M3Y0T6_MUSPFUncharacterized protein. (403 aa)
HCLS1Hematopoietic cell-specific Lyn substrate 1. (474 aa)
CNOT1CCR4-NOT transcription complex subunit 1. (2376 aa)
GTF2BGeneral transcription factor IIB. (316 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (447 aa)
FAM162AFamily with sequence similarity 162 member A. (155 aa)
PARP9Poly [ADP-ribose] polymerase. (995 aa)
DTX3LDeltex E3 ubiquitin ligase 3L. (745 aa)
RESTRE1 silencing transcription factor. (1098 aa)
ZBTB7AZinc finger and BTB domain containing 7A. (550 aa)
MED12Mediator complex subunit 12. (2168 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1013 aa)
M3XZP3_MUSPFHMG box domain-containing protein. (215 aa)
CRXCone-rod homeobox. (299 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (388 aa)
ARNTAryl hydrocarbon receptor nuclear translocator. (719 aa)
NCOA7Nuclear receptor coactivator 7. (970 aa)
WIPI1WD repeat domain, phosphoinositide interacting 1. (479 aa)
M3YT25_MUSPFUncharacterized protein; Belongs to the DEAD box helicase family. (372 aa)
M3YT91_MUSPFHMG box domain-containing protein. (411 aa)
TCF21Transcription factor 21. (179 aa)
MEF2DMyocyte enhancer factor 2D. (454 aa)
LRIF1Ligand dependent nuclear receptor interacting factor 1. (762 aa)
TP53BP2Tumor protein p53 binding protein 2. (1168 aa)
THRAP3Thyroid hormone receptor associated protein 3. (957 aa)
MED24Mediator complex subunit 24. (566 aa)
M3YU90_MUSPFMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (616 aa)
CREBBPCREB binding protein. (2442 aa)
M3YUH7_MUSPFWD_REPEATS_REGION domain-containing protein. (97 aa)
M3YUH8_MUSPFUncharacterized protein. (72 aa)
M3YUJ9_MUSPFHMG box domain-containing protein. (171 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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