STRINGSTRING
TREX1 TREX1 MAS1 MAS1 M3Z655_MUSPF M3Z655_MUSPF M3Z5Z4_MUSPF M3Z5Z4_MUSPF GPER1 GPER1 EPM2AIP1 EPM2AIP1 DYRK2 DYRK2 MID1IP1 MID1IP1 M3Z4M4_MUSPF M3Z4M4_MUSPF GCK GCK M3Z3A6_MUSPF M3Z3A6_MUSPF TRIB3 TRIB3 EIF6 EIF6 AKT2 AKT2 SNAI1 SNAI1 IFNG IFNG PPARG PPARG ERLIN1 ERLIN1 LPCAT3 LPCAT3 PPARGC1A PPARGC1A FOXK1 FOXK1 EP300 EP300 M3YY40_MUSPF M3YY40_MUSPF TSPO TSPO PPARA PPARA SLC7A11 SLC7A11 M3YXD0_MUSPF M3YXD0_MUSPF DNAJC30 DNAJC30 MLXIPL MLXIPL ANTKMT ANTKMT FIS1 FIS1 LPGAT1 LPGAT1 RD3 RD3 AKT3 AKT3 WDTC1 WDTC1 FMO4 FMO4 FMO1 FMO1 FMO2 FMO2 LOC101681442 LOC101681442 FMO3 FMO3 PDK2 PDK2 COX11 COX11 GIP GIP M3YUN0_MUSPF M3YUN0_MUSPF SCAP SCAP NR1D1 NR1D1 SEC14L5 SEC14L5 USP7 USP7 IGFBP4 IGFBP4 NOS2 NOS2 GPD1 GPD1 SOX9 SOX9 MFSD2A MFSD2A ZMPSTE24 ZMPSTE24 DDB1 DDB1 C1QTNF12 C1QTNF12 GUCA2B GUCA2B GUCA2A GUCA2A GIT1 GIT1 PRMT3 PRMT3 CD74 CD74 APOB APOB TREML1 TREML1 TREM2 TREM2 MST1 MST1 PROX1 PROX1 M3YPP3_MUSPF M3YPP3_MUSPF GUCA1B GUCA1B GNMT GNMT SLC27A4 SLC27A4 M3YP04_MUSPF M3YP04_MUSPF BAD BAD LOC101677498 LOC101677498 M3YN49_MUSPF M3YN49_MUSPF PLA2G3 PLA2G3 CLN3 CLN3 C1QTNF6 C1QTNF6 STARD4 STARD4 ARL2 ARL2 C1QTNF1 C1QTNF1 FGFR4 FGFR4 SLC2A6 SLC2A6 WDR5 WDR5 CRY1 CRY1 APPL2 APPL2 AVPR1B AVPR1B CYP27C1 CYP27C1 PRKCE PRKCE IGF1 IGF1 SIRT1 SIRT1 SLC45A3 SLC45A3 MALRD1 MALRD1 M3YKG8_MUSPF M3YKG8_MUSPF M3YKG1_MUSPF M3YKG1_MUSPF IER3 IER3 ATP2B4 ATP2B4 NR1H4 NR1H4 BCKDK BCKDK M3YJ43_MUSPF M3YJ43_MUSPF CLYBL CLYBL TNF TNF ATPSCKMT ATPSCKMT DGKQ DGKQ ADIPOR1 ADIPOR1 LHR LHR M3YHM7_MUSPF M3YHM7_MUSPF ACADM ACADM SNAI2 SNAI2 RANBP2 RANBP2 NCOA2 NCOA2 M3YGT2_MUSPF M3YGT2_MUSPF ACADVL ACADVL POU1F1 POU1F1 KAT2A KAT2A STAT3 STAT3 CYP7A1 CYP7A1 PIBF1 PIBF1 NCOR1 NCOR1 GUCA1C GUCA1C ERLIN2 ERLIN2 M3YEG5_MUSPF M3YEG5_MUSPF M3YEF8_MUSPF M3YEF8_MUSPF P2RY6 P2RY6 M3YE86_MUSPF M3YE86_MUSPF BEND3 BEND3 INSIG1 INSIG1 SLC4A1 SLC4A1 EGR1 EGR1 TIGAR TIGAR MLYCD MLYCD TFF3 TFF3 TP53 TP53 PRKAG2 PRKAG2 ANXA1 ANXA1 ELOVL5 ELOVL5 PANK2 PANK2 MIDN MIDN ABCD1 ABCD1 INSR INSR FGF1 FGF1 CBFA2T3 CBFA2T3 NOS3 NOS3 SLC7A7 SLC7A7 CAV1 CAV1 TTC39A TTC39A PRXL2C PRXL2C FAM3C FAM3C FBP1 FBP1 PARK7 PARK7 HIF1A HIF1A BMP2 BMP2 H6PD H6PD LDLR LDLR IGF2 IGF2 INS INS ARV1 ARV1 PDZD3 PDZD3 ABCG4 ABCG4 PLIN5 PLIN5 OGT OGT GPLD1 GPLD1 NR1H3 NR1H3 SIRT6 SIRT6 REST REST ZBTB7A ZBTB7A FGF19 FGF19 M3XZR5_MUSPF M3XZR5_MUSPF M3XZQ7_MUSPF M3XZQ7_MUSPF PARP1 PARP1 ATCAY ATCAY PTPN2 PTPN2 SLC35B4 SLC35B4 TYSND1 TYSND1 PID1 PID1 APOA1 APOA1 GFI1 GFI1 DDIT4 DDIT4 TTC39B TTC39B M3XXQ8_MUSPF M3XXQ8_MUSPF SPHK2 SPHK2 KCNMA1 KCNMA1 PPARD PPARD DUSP12 DUSP12 ADIPOQ ADIPOQ SERPINA12 SERPINA12 ACTN3 ACTN3 SIRT4 SIRT4 LONP2 LONP2 CLCN2 CLCN2 BMP5 BMP5 DKKL1 DKKL1 ACMSD ACMSD PPTC7 PPTC7 AKT1 AKT1 P2RX7 P2RX7 CYP27B1 CYP27B1 NR1H2 NR1H2 PDK4 PDK4 HTR2A HTR2A NCOR2 NCOR2 ZNF692 ZNF692 M3XP97_MUSPF M3XP97_MUSPF INSIG2 INSIG2 PTK2B PTK2B PDK1 PDK1 RORA RORA ABCB11 ABCB11 LEPR LEPR SIRT5 SIRT5 FMO5 FMO5 BMP6 BMP6 ZBTB20 ZBTB20 ABCD2 ABCD2 DNM1L DNM1L ETFBKMT ETFBKMT HDAC4 HDAC4 ERFE ERFE PDK3 PDK3 SREBF1 SREBF1 FLCN FLCN M3YP02_MUSPF M3YP02_MUSPF PTH PTH M3YNS7_MUSPF M3YNS7_MUSPF DKK3 DKK3 SEC14L3 SEC14L3 SEC14L4 SEC14L4
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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TREX1Three prime repair exonuclease 1. (313 aa)
MAS1MAS1 proto-oncogene, G protein-coupled receptor; Belongs to the G-protein coupled receptor 1 family. (325 aa)
M3Z655_MUSPFFABP domain-containing protein. (134 aa)
M3Z5Z4_MUSPFFABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (359 aa)
EPM2AIP1EPM2A interacting protein 1. (608 aa)
DYRK2Dual specificity tyrosine phosphorylation regulated kinase 2. (528 aa)
MID1IP1MID1 interacting protein 1. (183 aa)
M3Z4M4_MUSPFUncharacterized protein. (588 aa)
GCKPhosphotransferase. (473 aa)
M3Z3A6_MUSPFThyroglobulin type-1 domain-containing protein. (186 aa)
TRIB3Tribbles pseudokinase 3. (358 aa)
EIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (245 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity). (166 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (475 aa)
ERLIN1ER lipid raft associated 1. (310 aa)
LPCAT3Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (487 aa)
PPARGC1APPARG coactivator 1 alpha. (796 aa)
FOXK1Forkhead box K1. (614 aa)
EP300E1A binding protein p300. (2425 aa)
M3YY40_MUSPFDUF3496 domain-containing protein. (376 aa)
TSPOTranslocator protein. (169 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
SLC7A11Solute carrier family 7 member 11. (503 aa)
M3YXD0_MUSPFFork-head domain-containing protein. (575 aa)
DNAJC30DnaJ heat shock protein family (Hsp40) member C30. (220 aa)
MLXIPLMLX interacting protein like. (857 aa)
ANTKMTAdenine nucleotide translocase lysine methyltransferase. (182 aa)
FIS1Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa)
LPGAT1Lysophosphatidylglycerol acyltransferase 1. (370 aa)
RD3Retinal degeneration 3, GUCY2D regulator. (197 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (488 aa)
WDTC1WD and tetratricopeptide repeats 1. (679 aa)
FMO4Dimethylaniline monooxygenase [N-oxide-forming]. (556 aa)
FMO1Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa)
FMO2Dimethylaniline monooxygenase [N-oxide-forming]. (539 aa)
LOC101681442Dimethylaniline monooxygenase [N-oxide-forming]. (534 aa)
FMO3Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa)
PDK2Protein-serine/threonine kinase. (482 aa)
COX11Cytochrome c oxidase copper chaperone COX11. (279 aa)
GIPGastric inhibitory polypeptide. (144 aa)
M3YUN0_MUSPFC1q domain-containing protein. (306 aa)
SCAPSREBF chaperone. (1278 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (613 aa)
SEC14L5SEC14 like lipid binding 5. (695 aa)
USP7Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1055 aa)
IGFBP4Insulin like growth factor binding protein 4. (279 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1064 aa)
GPD1Glycerol-3-phosphate dehydrogenase [NAD(+)]. (350 aa)
SOX9SRY-box transcription factor 9. (522 aa)
MFSD2AMajor facilitator superfamily domain containing 2A. (529 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
DDB1Damage specific DNA binding protein 1. (1114 aa)
C1QTNF12C1q and TNF related 12. (305 aa)
GUCA2BGuanylate cyclase activator 2B. (116 aa)
GUCA2AGuanylate cyclase activator 2A. (108 aa)
GIT1GIT ArfGAP 1. (708 aa)
PRMT3Protein arginine methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (531 aa)
CD74CD74 molecule. (279 aa)
APOBApolipoprotein B. (4480 aa)
TREML1Triggering receptor expressed on myeloid cells like 1. (314 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (230 aa)
MST1Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. (711 aa)
PROX1Prospero homeobox 1. (737 aa)
M3YPP3_MUSPFUncharacterized protein. (204 aa)
GUCA1BGuanylate cyclase activator 1B. (201 aa)
GNMTGlycine N-methyltransferase. (226 aa)
SLC27A4Solute carrier family 27 member 4. (651 aa)
M3YP04_MUSPFUncharacterized protein. (675 aa)
BADBCL2 associated agonist of cell death. (168 aa)
LOC101677498DUF3496 domain-containing protein. (265 aa)
M3YN49_MUSPFUncharacterized protein. (176 aa)
PLA2G3Phospholipase A2 group III. (510 aa)
CLN3Battenin. (438 aa)
C1QTNF6C1q and TNF related 6. (265 aa)
STARD4StAR related lipid transfer domain containing 4. (179 aa)
ARL2ARL2-SNX15 readthrough (NMD candidate); Belongs to the small GTPase superfamily. Arf family. (184 aa)
C1QTNF1C1q and TNF related 1. (331 aa)
FGFR4Fibroblast growth factor receptor. (801 aa)
SLC2A6Solute carrier family 2 member 6; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (495 aa)
WDR5WD repeat domain 5. (334 aa)
CRY1Cryptochrome circadian regulator 1. (587 aa)
APPL2Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (660 aa)
AVPR1BVasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (421 aa)
CYP27C1Cytochrome P450 family 27 subfamily C member 1; Belongs to the cytochrome P450 family. (416 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa)
IGF1Insulin like growth factor 1. (153 aa)
SIRT1Sirtuin 1. (557 aa)
SLC45A3Solute carrier family 45 member 3. (552 aa)
MALRD1MAM and LDL receptor class A domain containing 1. (1452 aa)
M3YKG8_MUSPFMAM domain-containing protein. (110 aa)
M3YKG1_MUSPFUncharacterized protein. (352 aa)
IER3Immediate early response 3. (155 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1206 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (472 aa)
BCKDKProtein-serine/threonine kinase. (412 aa)
M3YJ43_MUSPFLeucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. (339 aa)
CLYBLCitrate lyase beta like. (326 aa)
TNFTumor necrosis factor alpha; Belongs to the tumor necrosis factor family. (233 aa)
ATPSCKMTATP synthase c subunit lysine N-methyltransferase. (213 aa)
DGKQDiacylglycerol kinase. (952 aa)
ADIPOR1Adiponectin receptor 1. (375 aa)
LHRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (692 aa)
M3YHM7_MUSPFFork-head domain-containing protein. (528 aa)
ACADMAcyl-CoA dehydrogenase medium chain. (421 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
RANBP2RAN binding protein 2. (2857 aa)
NCOA2DUF1518 domain-containing protein. (1226 aa)
M3YGT2_MUSPFUncharacterized protein. (219 aa)
ACADVLAcyl-CoA dehydrogenase very long chain. (579 aa)
POU1F1POU domain protein. (357 aa)
KAT2ALysine acetyltransferase 2A. (869 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
CYP7A1Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (501 aa)
PIBF1Progesterone immunomodulatory binding factor 1. (757 aa)
NCOR1Nuclear receptor corepressor 1. (2510 aa)
GUCA1CGuanylate cyclase activator 1C. (201 aa)
ERLIN2ER lipid raft associated 2. (337 aa)
M3YEG5_MUSPFBreast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (766 aa)
M3YEF8_MUSPFFOXO-TAD domain-containing protein. (399 aa)
P2RY6Pyrimidinergic receptor P2Y6. (395 aa)
M3YE86_MUSPFUncharacterized protein. (766 aa)
BEND3BEN domain containing 3. (830 aa)
INSIG1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. (113 aa)
SLC4A1Anion exchange protein. (924 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (544 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (270 aa)
MLYCDMalonyl-CoA decarboxylase. (316 aa)
TFF3Trefoil factor 3. (80 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (375 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (529 aa)
ANXA1Annexin. (345 aa)
ELOVL5Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] (352 aa)
PANK2Pantothenate kinase 2. (462 aa)
MIDNMidnolin. (460 aa)
ABCD1ATP binding cassette subfamily D member 1. (733 aa)
INSRTyrosine-protein kinase receptor. (1352 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
CBFA2T3CBFA2/RUNX1 partner transcriptional co-repressor 3. (630 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1211 aa)
SLC7A7Solute carrier family 7 member 7. (575 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
TTC39ATetratricopeptide repeat domain 39A. (578 aa)
PRXL2CPeroxiredoxin like 2C. (232 aa)
FAM3CFamily with sequence similarity 3 member C. (227 aa)
FBP1Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (338 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (824 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
H6PDHexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. (804 aa)
LDLRLow density lipoprotein receptor. (856 aa)
IGF2Insulin like growth factor 2. (192 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (109 aa)
ARV1ARV1 homolog, fatty acid homeostasis modulator. (282 aa)
PDZD3PDZ domain containing 3. (505 aa)
ABCG4ATP binding cassette subfamily G member 4. (646 aa)
PLIN5Perilipin; Belongs to the perilipin family. (480 aa)
OGTO-linked N-acetylglucosamine (GlcNAc) transferase. (1047 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (875 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (447 aa)
SIRT6Sirtuin 6. (359 aa)
RESTRE1 silencing transcription factor. (1098 aa)
ZBTB7AZinc finger and BTB domain containing 7A. (550 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (219 aa)
M3XZR5_MUSPFRBR-type E3 ubiquitin transferase. (115 aa)
M3XZQ7_MUSPFUbiquitin-like domain-containing protein. (311 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1013 aa)
ATCAYATCAY kinesin light chain interacting caytaxin. (371 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (388 aa)
SLC35B4Solute carrier family 35 member B4. (330 aa)
TYSND1Trypsin domain containing 1. (631 aa)
PID1Phosphotyrosine interaction domain containing 1. (217 aa)
APOA1Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family. (323 aa)
GFI1Growth factor independent 1 transcriptional repressor. (386 aa)
DDIT4DNA damage inducible transcript 4. (230 aa)
TTC39BTetratricopeptide repeat domain 39B. (682 aa)
M3XXQ8_MUSPFDimethylaniline monooxygenase [N-oxide-forming]. (533 aa)
SPHK2Sphingosine kinase 2. (673 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1020 aa)
PPARDPeroxisome proliferator activated receptor delta. (366 aa)
DUSP12Dual specificity phosphatase 12. (340 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (244 aa)
SERPINA12Serpin family A member 12; Belongs to the serpin family. (414 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (904 aa)
SIRT4NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (314 aa)
LONP2Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. (852 aa)
CLCN2Chloride channel protein. (903 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
DKKL1Dickkopf like acrosomal protein 1. (233 aa)
ACMSD2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. (270 aa)
PPTC7Protein phosphatase; Belongs to the PP2C family. (231 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (594 aa)
CYP27B1Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (515 aa)
NR1H2Nuclear receptor subfamily 1 group H member 2. (460 aa)
PDK4Protein-serine/threonine kinase. (412 aa)
HTR2A5-hydroxytryptamine receptor 2A. (470 aa)
NCOR2Nuclear receptor corepressor 2. (2525 aa)
ZNF692Zinc finger protein 692. (514 aa)
M3XP97_MUSPFANK_REP_REGION domain-containing protein. (132 aa)
INSIG2Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (225 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
PDK1Protein-serine/threonine kinase. (378 aa)
RORARAR related orphan receptor A. (430 aa)
ABCB11ATP binding cassette subfamily B member 11. (1325 aa)
LEPRLeptin receptor. (1164 aa)
SIRT5NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Modulates ketogenesis through the desuccinyl [...] (310 aa)
FMO5Dimethylaniline monooxygenase [N-oxide-forming]. (533 aa)
BMP6Bone morphogenetic protein 6. (426 aa)
ZBTB20Zinc finger and BTB domain containing 20. (741 aa)
ABCD2ATP binding cassette subfamily D member 2. (742 aa)
DNM1LDynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (749 aa)
ETFBKMTElectron transfer flavoprotein subunit beta lysine methyltransferase. (266 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1083 aa)
ERFEErythroferrone. (402 aa)
PDK3Protein-serine/threonine kinase. (415 aa)
SREBF1Sterol regulatory element binding transcription factor 1. (1147 aa)
FLCNUDENN FLCN/SMCR8-type domain-containing protein. (579 aa)
M3YP02_MUSPFPCAF_N domain-containing protein. (92 aa)
PTHParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (115 aa)
M3YNS7_MUSPFUncharacterized protein. (403 aa)
DKK3Dickkopf WNT signaling pathway inhibitor 3. (348 aa)
SEC14L3SEC14 like lipid binding 3. (400 aa)
SEC14L4SEC14 like lipid binding 4. (397 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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