STRINGSTRING
IL2 IL2 ST3GAL1 ST3GAL1 GPAM GPAM BCL11B BCL11B FADD FADD DOCK8 DOCK8 BCL10 BCL10 BMP4 BMP4 EFNA1 EFNA1 IDO1 IDO1 BCL3 BCL3 HIF1A HIF1A ADA ADA ARG2 ARG2 SLC46A2 SLC46A2 AURKB AURKB PIP PIP M3YPD2_MUSPF M3YPD2_MUSPF CD74 CD74 NOC2L NOC2L KIFAP3 KIFAP3 HSH2D HSH2D PRKCQ PRKCQ CD27 CD27 FOXP1 FOXP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (152 aa)
ST3GAL1ST3 beta-galactoside alpha-2,3-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (342 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (828 aa)
BCL11BBAF chromatin remodeling complex subunit BCL11B. (585 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (216 aa)
DOCK8Dedicator of cytokinesis 8; Belongs to the DOCK family. (2096 aa)
BCL10BCL10 immune signaling adaptor. (241 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (175 aa)
IDO1Indoleamine 2,3-dioxygenase 1. (394 aa)
BCL3BCL3 transcription coactivator. (456 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (824 aa)
ADAAdenosine deaminase. (363 aa)
ARG2Arginase. (354 aa)
SLC46A2Solute carrier family 46 member 2. (475 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (344 aa)
PIPProlactin induced protein. (145 aa)
M3YPD2_MUSPFUncharacterized protein. (225 aa)
CD74CD74 molecule. (279 aa)
NOC2LNOC2 like nucleolar associated transcriptional repressor. (760 aa)
KIFAP3Kinesin associated protein 3. (793 aa)
HSH2DHematopoietic SH2 domain containing. (346 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
CD27CD27 molecule. (263 aa)
FOXP1Forkhead box P1. (676 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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