STRINGSTRING
M3XM17_MUSPF M3XM17_MUSPF STK25 STK25 RIPK1 RIPK1 FLT4 FLT4 TNFRSF19 TNFRSF19 STK39 STK39 PTK2B PTK2B XIAP XIAP TLR4 TLR4 TNFSF11 TNFSF11 M3XRQ8_MUSPF M3XRQ8_MUSPF HAND2 HAND2 NOX1 NOX1 MID1 MID1 TRAF3 TRAF3 MYD88 MYD88 TAOK3 TAOK3 NOD2 NOD2 HIPK2 HIPK2 TRPV4 TRPV4 TGFB2 TGFB2 CCL19 CCL19 CCL21 CCL21 M3XZP3_MUSPF M3XZP3_MUSPF FGF19 FGF19 MAP3K4 MAP3K4 NOD1 NOD1 KLHDC10 KLHDC10 BMP4 BMP4 F2RL1 F2RL1 MAPK8IP1 MAPK8IP1 RELL1 RELL1 IGFBP6 IGFBP6 BMP2 BMP2 PLCB1 PLCB1 LEP LEP GADD45B GADD45B MMP8 MMP8 WNT16 WNT16 RB1CC1 RB1CC1 DAB2IP DAB2IP SH3RF1 SH3RF1 TRAF1 TRAF1 SH3RF2 SH3RF2 BIRC7 BIRC7 RELL2 RELL2 M3YA49_MUSPF M3YA49_MUSPF M3YA60_MUSPF M3YA60_MUSPF RASSF2 RASSF2 GDF6 GDF6 ANKRD6 ANKRD6 CRACR2A CRACR2A EIF2AK2 EIF2AK2 AGER AGER LYN LYN INAVA INAVA SH3RF3 SH3RF3 EDAR EDAR RIPK2 RIPK2 TRAF2 TRAF2 RETREG1 RETREG1 ZNF622 ZNF622 TLR3 TLR3 SEMA4C SEMA4C TNF TNF MFHAS1 MFHAS1 PYCARD PYCARD CARD9 CARD9 TRAF6 TRAF6 MAP3K11 MAP3K11 MAP4K2 MAP4K2 PJA2 PJA2 SERPINF2 SERPINF2 SPHK1 SPHK1 UNC5CL UNC5CL TRAF4 TRAF4 M3YRT8_MUSPF M3YRT8_MUSPF RAB44 RAB44 TPD52L1 TPD52L1 CCN2 CCN2 ZC3H12A ZC3H12A MAP3K5 MAP3K5 MAP3K3 MAP3K3 M3YUJ9_MUSPF M3YUJ9_MUSPF STK3 STK3 TRAF5 TRAF5 AXIN1 AXIN1 NCF1 NCF1 WNT7B WNT7B MBIP MBIP CD27 CD27 LTBR LTBR PDCD10 PDCD10 WNT7A WNT7A M3Z1D8_MUSPF M3Z1D8_MUSPF MAP3K10 MAP3K10 SASH1 SASH1 M3Z3T3_MUSPF M3Z3T3_MUSPF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
M3XM17_MUSPFUncharacterized protein. (208 aa)
STK25Serine/threonine kinase 25. (426 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (646 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1355 aa)
TNFRSF19TNF receptor superfamily member 19. (444 aa)
STK39Serine/threonine kinase 39. (546 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
XIAPX-linked inhibitor of apoptosis. (497 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (833 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (321 aa)
M3XRQ8_MUSPFUncharacterized protein. (262 aa)
HAND2Heart and neural crest derivatives expressed 2. (208 aa)
NOX1NADPH oxidase 1. (589 aa)
MID1Midline 1. (667 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (569 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
TAOK3TAO kinase 3. (914 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1013 aa)
HIPK2Homeodomain interacting protein kinase 2. (1165 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (873 aa)
TGFB2Transforming growth factor beta-2 proprotein; Transforming growth factor beta-2 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively. Transforming growth factor beta-2: Multifunctional protein that regulates various processes such as angiogenesis and heart development (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transfor [...] (414 aa)
CCL19C-C motif chemokine. (108 aa)
CCL21SCY domain-containing protein. (137 aa)
M3XZP3_MUSPFHMG box domain-containing protein. (215 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (219 aa)
MAP3K4Mitogen-activated protein kinase kinase kinase 4. (1463 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (952 aa)
KLHDC10Kelch domain containing 10. (444 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
F2RL1F2R like trypsin receptor 1. (397 aa)
MAPK8IP1Mitogen-activated protein kinase 8 interacting protein 1. (703 aa)
RELL1RELT like 1. (271 aa)
IGFBP6Insulin-like growth factor-binding protein 6. (237 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1096 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (166 aa)
GADD45BGrowth arrest and DNA damage inducible beta. (160 aa)
MMP8Matrix metallopeptidase 8. (473 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa)
RB1CC1RB1 inducible coiled-coil 1. (1593 aa)
DAB2IPDAB2 interacting protein. (1112 aa)
SH3RF1SH3 domain containing ring finger 1. (880 aa)
TRAF1TNF receptor-associated factor. (415 aa)
SH3RF2SH3 domain containing ring finger 2. (733 aa)
BIRC7Baculoviral IAP repeat containing 7. (300 aa)
RELL2RELT like 2. (303 aa)
M3YA49_MUSPFUncharacterized protein. (659 aa)
M3YA60_MUSPFN-terminal Ras-GEF domain-containing protein. (178 aa)
RASSF2Ras association domain family member 2. (326 aa)
GDF6Growth differentiation factor 6. (434 aa)
ANKRD6Ankyrin repeat domain 6. (727 aa)
CRACR2ACalcium release activated channel regulator 2A. (709 aa)
EIF2AK2Eukaryotic translation initiation factor 2 alpha kinase 2. (518 aa)
AGERAdvanced glycosylation end-product specific receptor. (400 aa)
LYNTyrosine-protein kinase. (512 aa)
INAVAInnate immunity activator. (656 aa)
SH3RF3SH3 domain containing ring finger 3. (695 aa)
EDAREctodysplasin A receptor. (459 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (569 aa)
RETREG1Reticulophagy regulator 1. (362 aa)
ZNF622Zinc finger protein 622. (475 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (764 aa)
SEMA4CSemaphorin 4C; Belongs to the semaphorin family. (867 aa)
TNFTumor necrosis factor alpha; Belongs to the tumor necrosis factor family. (233 aa)
MFHAS1Malignant fibrous histiocytoma amplified sequence 1. (1052 aa)
PYCARDPYD and CARD domain containing. (193 aa)
CARD9Caspase recruitment domain family member 9. (478 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
MAP3K11Mitogen-activated protein kinase kinase kinase. (863 aa)
MAP4K2Mitogen-activated protein kinase kinase kinase kinase 2; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (847 aa)
PJA2Praja ring finger ubiquitin ligase 2. (710 aa)
SERPINF2Serpin family F member 2; Belongs to the serpin family. (491 aa)
SPHK1Sphingosine kinase 1. (386 aa)
UNC5CLUnc-5 family C-terminal like. (550 aa)
TRAF4TNF receptor-associated factor. (470 aa)
M3YRT8_MUSPFIg-like domain-containing protein. (339 aa)
RAB44Uncharacterized protein. (245 aa)
TPD52L1TPD52 like 1. (209 aa)
CCN2Cellular communication network factor 2. (349 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (576 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1398 aa)
MAP3K3Mitogen-activated protein kinase kinase kinase 3. (647 aa)
M3YUJ9_MUSPFHMG box domain-containing protein. (171 aa)
STK3Serine/threonine kinase 3. (418 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (558 aa)
AXIN1Axin 1. (862 aa)
NCF1Neutrophil cytosolic factor 1. (391 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
MBIPMAP3K12 binding inhibitory protein 1. (344 aa)
CD27CD27 molecule. (263 aa)
LTBRLymphotoxin beta receptor. (420 aa)
PDCD10Programmed cell death 10. (212 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
M3Z1D8_MUSPFUncharacterized protein. (40 aa)
MAP3K10Mitogen-activated protein kinase kinase kinase. (936 aa)
SASH1SAM and SH3 domain containing 1. (1145 aa)
M3Z3T3_MUSPFUncharacterized protein. (262 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.