STRINGSTRING
M3XLU3_MUSPF M3XLU3_MUSPF FGF16 FGF16 VAV3 VAV3 CNTF CNTF IRAK4 IRAK4 SNX1 SNX1 FGF9 FGF9 IL23R IL23R RNF41 RNF41 KL KL EFEMP1 EFEMP1 VEGFD VEGFD MYD88 MYD88 FAM83B FAM83B IL12A IL12A PTPRJ PTPRJ FGF21 FGF21 FGF17 FGF17 SNX4 SNX4 GLMN GLMN ERAP1 ERAP1 FGF19 FGF19 FGF4 FGF4 M3XZV6_MUSPF M3XZV6_MUSPF ECM1 ECM1 CDH5 CDH5 PDCL2 PDCL2 PDGFRA PDGFRA KLB KLB CBLC CBLC PDGFD PDGFD FGF5 FGF5 TGFA TGFA DAB2IP DAB2IP IL11 IL11 IL6ST IL6ST ERBB4 ERBB4 FGF1 FGF1 M3Y9K9_MUSPF M3Y9K9_MUSPF HBEGF HBEGF BTC BTC AREG AREG EREG EREG EPGN EPGN PGF PGF FGF6 FGF6 FGF23 FGF23 IL1RN IL1RN IL1F10 IL1F10 IL36RN IL36RN M3YDW1_MUSPF M3YDW1_MUSPF IL36G IL36G IL1A IL1A RNF126 RNF126 FGF22 FGF22 IL9 IL9 IL7 IL7 PIBF1 PIBF1 CCDC88A CCDC88A IL4 IL4 IL1B IL1B PYCARD PYCARD CSF2 CSF2 M3YJF2_MUSPF M3YJF2_MUSPF VEGFC VEGFC PDCL3 PDCL3 VAV2 VAV2 FGF7 FGF7 FER FER VEGFA VEGFA FGF18 FGF18 SNX2 SNX2 VEGFB VEGFB PDGFB PDGFB FRS3 FRS3 IL6 IL6 ARTN ARTN GRB2 GRB2 AGR2 AGR2 NCSTN NCSTN SLC9A3R1 SLC9A3R1 ESM1 ESM1 FGF10 FGF10 MS4A15 MS4A15 LOC101671307 LOC101671307 LOC101674109 LOC101674109 ERN1 ERN1 GDNF GDNF CSF3 CSF3 IL12RB1 IL12RB1 GATA3 GATA3 CNOT9 CNOT9 FGF8 FGF8 NPTN NPTN LINGO1 LINGO1 FGF2 FGF2 IL21 IL21 IL2 IL2 FRS2 FRS2 TIMM50 TIMM50 SRC SRC PDGFA PDGFA FGF20 FGF20 FLRT3 FLRT3 FLRT2 FLRT2 LINGO2 LINGO2 GREM1 GREM1 SOCS5 SOCS5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
M3XLU3_MUSPFUncharacterized protein. (309 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
VAV3Vav guanine nucleotide exchange factor 3. (847 aa)
CNTFCiliary neurotrophic factor. (200 aa)
IRAK4Interleukin-1 receptor-associated kinase 4. (460 aa)
SNX1Sorting nexin 1. (364 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
IL23RInterleukin 23 receptor. (632 aa)
RNF41Ring finger protein 41. (317 aa)
KLKlotho. (987 aa)
EFEMP1EGF containing fibulin extracellular matrix protein 1. (502 aa)
VEGFDVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
FAM83BFamily with sequence similarity 83 member B. (1011 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (222 aa)
PTPRJProtein tyrosine phosphatase receptor type J. (1219 aa)
FGF21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
SNX4Sorting nexin 4. (450 aa)
GLMNGlomulin, FKBP associated protein. (600 aa)
ERAP1Aminopeptidase. (942 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (219 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
M3XZV6_MUSPFFibroblast growth factor; Belongs to the heparin-binding growth factors family. (153 aa)
ECM1Extracellular matrix protein 1. (564 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (783 aa)
PDCL2Phosducin like 2. (242 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1087 aa)
KLBKlotho beta. (850 aa)
CBLCCbl proto-oncogene C. (516 aa)
PDGFDPlatelet derived growth factor D. (364 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (265 aa)
TGFATransforming growth factor alpha. (158 aa)
DAB2IPDAB2 interacting protein. (1112 aa)
IL11Interleukin 11. (197 aa)
IL6STInterleukin 6 signal transducer. (918 aa)
ERBB4Receptor protein-tyrosine kinase. (1224 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
M3Y9K9_MUSPFIntegrin beta; Belongs to the integrin beta chain family. (645 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
BTCBetacellulin. (185 aa)
AREGAmphiregulin. (283 aa)
EREGEpiregulin. (161 aa)
EPGNEpithelial mitogen. (153 aa)
PGFPlacental growth factor; Belongs to the PDGF/VEGF growth factor family. (170 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (245 aa)
IL1RNInterleukin-1. (158 aa)
IL1F10Interleukin-1. (152 aa)
IL36RNInterleukin-1. (156 aa)
M3YDW1_MUSPFInterleukin-1. (183 aa)
IL36GInterleukin-1. (156 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (270 aa)
RNF126Ring finger protein 126. (315 aa)
FGF22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (170 aa)
IL9Interleukin 9. (143 aa)
IL7Interleukin 7. (158 aa)
PIBF1Progesterone immunomodulatory binding factor 1. (757 aa)
CCDC88ACoiled-coil domain containing 88A. (1824 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (132 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (168 aa)
PYCARDPYD and CARD domain containing. (193 aa)
CSF2Colony stimulating factor 2. (148 aa)
M3YJF2_MUSPFUncharacterized protein. (140 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (370 aa)
PDCL3Phosducin like 3. (240 aa)
VAV2Vav guanine nucleotide exchange factor 2. (834 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (823 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (398 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
SNX2Sorting nexin 2. (519 aa)
VEGFBVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (188 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (242 aa)
FRS3Fibroblast growth factor receptor substrate 3. (513 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (210 aa)
ARTNArtemin. (168 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
AGR2Anterior gradient 2, protein disulphide isomerase family member. (175 aa)
NCSTNNicastrin. (729 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (366 aa)
ESM1Endothelial cell-specific molecule 1. (183 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
MS4A15Membrane spanning 4-domains A15. (257 aa)
LOC101671307Uncharacterized protein. (235 aa)
LOC101674109Uncharacterized protein. (230 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (975 aa)
GDNFGlial cell derived neurotrophic factor. (211 aa)
CSF3Colony stimulating factor 3. (204 aa)
IL12RB1Interleukin 12 receptor subunit beta 1. (716 aa)
GATA3GATA binding protein 3. (444 aa)
CNOT9CCR4-NOT transcription complex subunit 9. (299 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (247 aa)
NPTNNeuroplastin. (398 aa)
LINGO1Leucine rich repeat and Ig domain containing 1. (620 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (153 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (152 aa)
FRS2Fibroblast growth factor receptor substrate 2. (517 aa)
TIMM50Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (355 aa)
SRCTyrosine-protein kinase. (536 aa)
PDGFAPlatelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
FLRT3Fibronectin leucine rich transmembrane protein 3. (649 aa)
FLRT2Fibronectin leucine rich transmembrane protein 2. (660 aa)
LINGO2Leucine rich repeat and Ig domain containing 2. (606 aa)
GREM1Gremlin. (184 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
Your Current Organism:
Mustela putorius
NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret
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