(20 nodes) Cellular response to estradiol stimulus network (Mustela putorius)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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Predicted Interactions

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Your Input:
	KAT5	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa)
	RUVBL2	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa)
	M3XRV6_MUSPF	Uncharacterized protein. (351 aa)
	CRHBP	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa)
	M3Y377_MUSPF	NTR domain-containing protein. (233 aa)
	FAM210B	Family with sequence similarity 210 member B. (192 aa)
	ESR2	Estrogen receptor 2. (521 aa)
	H2AZ1	Histone H2A; Belongs to the histone H2A family. (128 aa)
	ZNF703	Zinc finger protein 703. (545 aa)
	ESR1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (597 aa)
	MYOD1	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
	NCOA3	Nuclear receptor coactivator. (1416 aa)
	EGFR	Receptor protein-tyrosine kinase. (1207 aa)
	RAMP3	Receptor activity modifying protein 3. (149 aa)
	H2AZ2	Histone H2A; Belongs to the histone H2A family. (148 aa)
	GPER1	G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (359 aa)
	NRIP1	Nuclear receptor interacting protein 1. (1156 aa)
	SSTR3	Somatostatin receptor 3; Belongs to the G-protein coupled receptor 1 family. (419 aa)
	SSTR1	Somatostatin receptor 1; Belongs to the G-protein coupled receptor 1 family. (391 aa)
	SSTR5	Somatostatin receptor 5; Belongs to the G-protein coupled receptor 1 family. (365 aa)

Your Current Organism:

Mustela putorius

NCBI taxonomy Id: 9669
Other names: M. putorius furo, Mustela furo, Mustela putorius furo, black ferret, domestic ferret, ferret

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EGFR	ESR1	ENSMPUP00000018042	ENSMPUP00000010404	Receptor protein-tyrosine kinase.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.863
EGFR	ESR2	ENSMPUP00000018042	ENSMPUP00000006634	Receptor protein-tyrosine kinase.	Estrogen receptor 2.	0.667
ESR1	EGFR	ENSMPUP00000010404	ENSMPUP00000018042	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Receptor protein-tyrosine kinase.	0.863
ESR1	ESR2	ENSMPUP00000010404	ENSMPUP00000006634	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Estrogen receptor 2.	0.977
ESR1	GPER1	ENSMPUP00000010404	ENSMPUP00000018928	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.703
ESR1	H2AZ1	ENSMPUP00000010404	ENSMPUP00000009443	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Histone H2A; Belongs to the histone H2A family.	0.409
ESR1	H2AZ2	ENSMPUP00000010404	ENSMPUP00000018077	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Histone H2A; Belongs to the histone H2A family.	0.409
ESR1	KAT5	ENSMPUP00000010404	ENSMPUP00000011528	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.651
ESR1	NCOA3	ENSMPUP00000010404	ENSMPUP00000017480	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Nuclear receptor coactivator.	0.993
ESR1	NRIP1	ENSMPUP00000010404	ENSMPUP00000019021	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Nuclear receptor interacting protein 1.	0.902
ESR2	EGFR	ENSMPUP00000006634	ENSMPUP00000018042	Estrogen receptor 2.	Receptor protein-tyrosine kinase.	0.667
ESR2	ESR1	ENSMPUP00000006634	ENSMPUP00000010404	Estrogen receptor 2.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.977
ESR2	GPER1	ENSMPUP00000006634	ENSMPUP00000018928	Estrogen receptor 2.	G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.877
ESR2	NCOA3	ENSMPUP00000006634	ENSMPUP00000017480	Estrogen receptor 2.	Nuclear receptor coactivator.	0.974
ESR2	NRIP1	ENSMPUP00000006634	ENSMPUP00000019021	Estrogen receptor 2.	Nuclear receptor interacting protein 1.	0.719
GPER1	ESR1	ENSMPUP00000018928	ENSMPUP00000010404	G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.703
GPER1	ESR2	ENSMPUP00000018928	ENSMPUP00000006634	G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family.	Estrogen receptor 2.	0.877
H2AZ1	ESR1	ENSMPUP00000009443	ENSMPUP00000010404	Histone H2A; Belongs to the histone H2A family.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.409
H2AZ1	KAT5	ENSMPUP00000009443	ENSMPUP00000011528	Histone H2A; Belongs to the histone H2A family.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.531
H2AZ1	RUVBL2	ENSMPUP00000009443	ENSMPUP00000003242	Histone H2A; Belongs to the histone H2A family.	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	0.816